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1101“…In SKBR3 and BT474 breast cancer cell lines treated with anti-HER2 therapies, MAF1 mRNA expression is significantly increased. …”
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1102por Fait, Tomas, Baltazár, Tivadar, Bubenickova, Leona, Kestranek, Jan, Stepan, Martin, Muller, Miroslav, Turcan, Pavel“…Aim: To evaluate the efficacy and safety of electroporation therapy treatment of vulvovaginal laxity by the Jett Plasma for Her II device. Methods: The Jett Plasma for Her II Study is a multicentric, prospective, randomized, single-blinded, and controlled study. …”
Publicado 2023
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1103por Ma, Youzhao, Zhu, Mingda, Zhang, Jingyang, Lv, Minhao, Chen, Xiuchun, Liu, Zhenzhen“…PURPOSE: Patients with human epidermal growth factor receptor 2 (HER2)–low advanced breast cancer can benefit from trastuzumab deruxtecan. …”
Publicado 2023
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1104
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1105por DiPeri, Timothy P., Evans, Kurt W., Raso, Maria Gabriela, Zhao, Ming, Rizvi, Yasmeen Q., Zheng, Xiaofeng, Wang, Bailiang, Kirby, Bryce P., Kong, Kathleen, Kahle, Michael, Yap, Timothy A., Dumbrava, Ecaterina E., Ajani, Jaffer A., Fu, Siqing, Keyomarsi, Khandan, Meric-Bernstam, Funda“…In vitro, CCNE1 was overexpressed or knocked down in HER2+ cell lines to evaluate drug combination efficacy. …”
Publicado 2023
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1106por McNamara, Blair, Greenman, Michelle, Pebley, Nicole, Mutlu, Levent, Santin, Alessandro D.“…One such tumor surface receptor is human epidermal growth factor 2 (HER2), which is of interest for the treatment of many gynecologic tumors. …”
Publicado 2023
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1107por Yang, Di, Wang, Bo, Li, Yinuo, Zhang, Jingyao, Gong, Xuantong, Qin, Hao, Wang, Yan, Zhao, Yahui, Wang, Yong“…Background: This study aimed to investigate the effect of increased HER-2 expression on tumor-infiltrating lymphocytes (TILs) and determine its impact on the prognosis of colorectal cancer (CRC) patients; Methods: HER-2, CD4, CD8, CD19, LY6G, CD56, CD68, CD11b, and EpCam expression in CRC tissues and adjacent paracancerous tissues were assessed using multiplex fluorescence immunohistochemical staining. …”
Publicado 2023
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1108
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1109por Juranic, Zorica D, Neskovic-Konstantinovic, Zora, Stanojkovic, Tatjana P, Zizak, Zeljko, Srdic, Tatjana, Stanojevic-Bakic, Nevenka, Milosevic, Dusanka, Jovanovic, Danica“…The aim of this study was to determine the basis for anti-tumor immune reactivity observed in patients with human epidermal growth factor receptor-2 (HER-2) (3+) breast carcinoma using an in vitro model in which the role of the HER-2-specific monoclonal antibody Herceptin was also investigated. …”
Publicado 2005
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1110por Miles, David W“…Further analysis also implies that cases which are positive for HER-2 by fluorescent in situ hybridization may also benefit from treatment regardless of whether they express HER-2 at the 2+ or 3+ level. …”
Publicado 2001
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1111por Wolf-Yadlin, Alejandro, Kumar, Neil, Zhang, Yi, Hautaniemi, Sampsa, Zaman, Muhammad, Kim, Hyung-Do, Grantcharova, Viara, Lauffenburger, Douglas A, White, Forest M“…Although human epidermal growth factor receptor 2 (HER2) overexpression is implicated in tumor progression for a variety of cancer types, how it dysregulates signaling networks governing cell behavioral functions is poorly understood. …”
Publicado 2006
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1112por Tapia, Coya, Savic, Spasenija, Wagner, Urs, Schönegg, René, Novotny, Hedvika, Grilli, Bruno, Herzog, Michelle, Barascud, Audrey DeVito, Zlobec, Inti, Cathomas, Gieri, Terracciano, Luigi, Feichter, Georg, Bubendorf, Lukas“…INTRODUCTION: The status of the gene encoding human EGF-like receptor 2 (HER2) is an important prognostic and predictive marker in breast cancer. …”
Publicado 2007
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1113por Bruynzeel, A M E, Abou El Hassan, M A, Torun, E, Bast, A, van der Vijgh, W J F, Kruyt, F A E“…To obtain more insight in the mechanism underlying the selective protective effects of monoHER, we investigated whether monoHER (1 mM) affects DOX-induced apoptosis in neonatal rat cardiac myocytes (NeRCaMs), human endothelial cells (HUVECs) and the ovarian cancer cell lines A2780 and OVCAR-3. …”
Publicado 2007
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1114“…Since human epidermal growth factor receptor 2 (HER2) is known to participate with the epidermal growth factor receptor (EGFR) in mitogenic signalling, we hypothesised that HER2 overexpression might indicate responsiveness to EGFR targeted therapies. …”
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1115por Kim, Yong-Seok, Won, Yong Sung, Park, Kyung Shin, Song, Byung Joo, Kim, Jeong Soo, Oh, Se Jeong, Jeon, Hae Myung, Jung, Sang Seol, Park, Woo-Chan“…It is well known that the amplification of the HER2 gene is closely associated with poor prognosis of breast cancer. …”
Publicado 2008
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1116por Jo, Uk Hyun, Han, Sle Gi Lo, Seo, Jae Hong, Park, Kyong Hwa, Lee, Jae Won, Lee, Hyo Jung, Ryu, Jeong Seon, Kim, Yeul Hong“…Amplification of the HER-2 gene has been reported in lung cancer, where it has been associated with poor prognosis. …”
Publicado 2008
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1117por Mori, N, Kyo, S, Nakamura, M, Hashimoto, M, Maida, Y, Mizumoto, Y, Takakura, M, Ohno, S, Kiyono, T, Inoue, M“…Gene amplification of HER-2 was observed in 2 of 26 patients with high HER-2 expression. …”
Publicado 2010
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1118por Di Modugno, Francesca, Mottolese, Marcella, DeMonte, Lucia, Trono, Paola, Balsamo, Michele, Conidi, Andrea, Melucci, Elisa, Terrenato, Irene, Belleudi, Francesca, Torrisi, Maria Rosaria, Alessio, Massimo, Santoni, Angela, Nisticò, Paola“…The aim of this study was to determine whether the hMena/hMena(11a) overexpression cooperates with HER-2 signalling, thereby affecting the HER2 mitogenic activity in breast cancer. …”
Publicado 2010
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1119
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1120por Moelans, Cathy B., Milne, Anya N., Morsink, Folkert H., Offerhaus, G. Johan A., van Diest, Paul J.“…RESULTS: Overall, we found only 5% HER2 high level amplification and 3% HER2 3+ overexpression (6/199). …”
Publicado 2011
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