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  1. 1221
    “…Human epidermal growth factor receptor (HER2) negative metastatic breast cancer (BC) accounts for 73% of BC. …”
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    Prospect for Application of PARP Inhibitor in Patients with HER2 Negative Breast Cancer
  2. 1222
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    When a Woman Kills Her Man: Gender and Victim Precipitation in Homicide
  3. 1223
    “…We recently reported the antitumor effect of a pan‐HER inhibitor, afatinib, against human epidermal growth factor receptor 2 (HER2)‐amplified gastric cancer cells. …”
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    Acquired resistance mechanisms to afatinib in HER2‐amplified gastric cancer cells
  4. 1224
    “…BACKGROUND: Trastuzumab is a drug that targets the receptor tyrosine kinase HER2 and is essential for the treatment of HER2-positive breast cancer. …”
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    Vasculogenic mimicry is associated with trastuzumab resistance of HER2-positive breast cancer
  5. 1225
    “…MATERIALS AND METHODS: The hybrid constructs were obtained by adding a Her2-binding peptide (H2.1) to MS1 and MS2 bioengineered silks based on the MaSp1 and MaSp2 proteins from N. clavipes, respectively. …”
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    Cellular uptake, intracellular distribution and degradation of Her2-targeting silk nanospheres
  6. 1226
    por Cools, Jan
    Publicado 2017
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    In memory of Tessa Holyoake and Her Work on Chronic Myeloid Leukemia Stem Cells
  7. 1227
    “…HER-2 amplification was not observed in any case. …”
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    Estrogen Receptor, Progesterone Receptor, and HER-2 Expression in Recurrent Pleomorphic Adenoma
  8. 1228
    “…The finding that the majority of OS overexpress the protooncogene HER2 raises the possibility of using HER2 as a therapeutic target. …”
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    Elimination of Osteosarcoma by Necroptosis with Graphene Oxide-Associated Anti-HER2 Antibodies
  9. 1229
    por Wang, Jiani, Xu, Binghe
    Publicado 2019
    “…Over the past 2 decades, there has been an extraordinary progress in the regimens developed for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer. Trastuzumab, pertuzumab, lapatinib, and ado-trastuzumab emtansine (T-DM1) are commonly recommended anti-HER2 target agents by the U.S. …”
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    Targeted therapeutic options and future perspectives for HER2-positive breast cancer
  10. 1230
    “…Immunotherapeutical agents represent an emerging option for breast cancer treatment, including the human epidermal growth factor 2 positive (HER2+) subtype. The immune system holds the ability to spontaneously implement a defensive response against HER2+ BC cells through complex mechanisms which can be exploited to modulate this response for obtaining a clinical benefit. …”
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    Immunotherapy in HER2-positive breast cancer: state of the art and future perspectives
  11. 1231
    “…BACKGROUND: The aberrant expression of HER2 is highly associated with tumour occurrence and metastasis, therefore HER2 is extensively targeted for tumour immunotherapy. …”
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    Identification of an Activating Mutation in the Extracellular Domain of HER2 Conferring Resistance to Pertuzumab
  12. 1232
    “…Human epidermal growth factor receptor 2 (HER2) protein overexpression and/or HER2 gene amplification is found in about 20% of invasive breast cancers. …”
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    HER2 status in breast cancer: changes in guidelines and complicating factors for interpretation
  13. 1233
    “…No clinicopathologic features were correlated with HER2 expression, but HER2 positivity was inversely associated with the degree of HER2 overexpression. …”
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    Estrogen Receptor, Progesterone Receptor, and HER2 Receptor Markers in Endometrial Cancer
  14. 1234
    “…A few previous studies have examined whether HER4 may promote the progression of CRC. The present study examined the associations among the expression levels of members of the HER family, and investigated the potential mechanism underlying the function of HER4 in CRC cells. …”
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    HER4 promotes the progression of colorectal cancer by promoting epithelial-mesenchymal transition
  15. 1235
    por Weigl, Josef
    Publicado 2020
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    Betrachtung der Pandemie Phase 3 – „mitigation“ – vom Endpunkt Hospitalisation her
  16. 1236
    “…Clinical progress in the field of HER2-positive breast cancer therapy has been dramatically improved by understanding of the immune regulatory mechanisms of tumor microenvironment. …”
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    HER2-Positive Breast Cancer Immunotherapy: A Focus on Vaccine Development
  17. 1237
    “…Three groups were compared: patients with HER2-positive MBC receiving ongoing HER2-targeted therapy (n = 28), patients with de novo HER2-positive MBC and no HER2-targeted therapy in the last 12 months prior to enrollment and start of HER2-targeted therapy (n = 15), and patients with HER2-nonamplified disease and no HER2-targeted therapy (n = 212). …”
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    HER2-targeted therapy influences CTC status in metastatic breast cancer
  18. 1238
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    Brachioradial pruritus in a patient with metastatic breast cancer to her cervical spine
  19. 1239
    “…To better understand the function of Her9 in the retina, we generated zebrafish her9 CRISPR mutants. …”
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    Her9/Hes4 is required for retinal photoreceptor development, maintenance, and survival
  20. 1240
    “…Throughout a honey bee queen’s lifetime, she is tended to by her worker daughters, who feed and groom her. Such interactions provide possible horizontal transmission routes for pathogens from the workers to the queen, and as such a queen’s pathogen profile may be representative of the workers within a colony. …”
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    The Pathogen Profile of a Honey Bee Queen Does Not Reflect That of Her Workers
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