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  1. 1461
    Publicado 1919
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    Viscount Burnham and Maitre De Leval on Nurse Cavell: Her Last Words Recorded
  2. 1462
    “…Here we show that the ERBB2 oncogene at 17q12 is susceptible to palindromic gene amplification, a mechanism characterized by the inverted (palindromic) duplication of genomic segments, in HER2-positive breast tumors. We applied two genomic approaches to investigate amplification mechanisms: sequencing of DNA libraries enriched with tumor-derived palindromic DNA (Genome-wide Analysis of Palindrome Formation) and whole genome sequencing (WGS). …”
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    Palindromic amplification of the ERBB2 oncogene in primary HER2-positive breast tumors
  3. 1463
    “…Herein, we compared the association between IHC with FISH in HER2-positive breast cancer patients and affection of trastuzumab on disease free survival and overall survival (OS). …”
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    Is There any Concordance between of IHC with FISH in HER2-Positive Breast Cancer Patients?
  4. 1464
    “…Together with this, we observed increased HER2:HER3 dimerization upon cetuximab treatment. …”
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    Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells
  5. 1465
    “…Immunohistochemical staining by Her2/neu was performed after complete surgical resection of the tumors with preservation of the pseudocapsule. …”
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    Prognostic Value of Her2/neu Expression in Gastrointestinal Stromal Tumors: Immunohistochemical Study
  6. 1466
    por Simpson, A. R.
    Publicado 1905
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    Heredity in Ovarian Cystoma: History of a Mother and Her Two Daughters Subjected to Ovariotomy
  7. 1467
    “…In particular, the overexpression of the human epidermal growth factor receptor 2 (HER2) by tumor cells provided a specific target in these HER2-positive tumors. …”
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    Emerging treatments for HER2-positive early-stage breast cancer: focus on neratinib
  8. 1468
    “…An approximate 20% of the cases overexpress HER2, and among them, the combination of chemotherapy with trastuzumab is actually the first-line palliative treatment. …”
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    The Effectiveness of Trastuzumab Combined with Sequential Chemotherapy for Metastatic Gastric Carcinoma with Overexpression of HER2
  9. 1469
    “…In recent years, significant efforts have been devoted to achieving specific and noninvasive HER2-positive breast cancer imaging in vivo. In this work, we reviewed existing literature on HER2 imaging in the past decade and summarized the studies from different points of view, such as imaging modalities and HER2-specific probes. …”
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    Preclinical and clinical applications of specific molecular imaging for HER2-positive breast cancer
  10. 1470
    Publicado 1819
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    Observations on Particular Modes of Treatment Recommended to Assist Nature in Her Efforts during Parturition
  11. 1471
    “…However, the prognostic value of HER2 status in gastric cancer remains controversial. …”
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    Clinicopathological factors associated with HER2-positive gastric cancer: A meta-analysis
  12. 1472
    “…MM-111, ertumaxomab) and activated T cells armed with anti-HER2 bispecific antibody (HER2Bi-aATC). Trastuzumab is a classic drug for the treatment of HER2 positive metastatic breast cancer. …”
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    Development and clinical application of anti-HER2 monoclonal and bispecific antibodies for cancer treatment
  13. 1473
    por Gibbon, James
    Publicado 1814
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    Review of the Case of Ann Fooks, with Arguments to Prove Her Having Practised a Deception
  14. 1474
    por Gibbon, James
    Publicado 1814
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    Review of the Case of Ann Fooks, with Arguments to Prove Her Having Practised a Deception
  15. 1475
    “…HER2 becomes the standard of care for guiding adjuvant treatment of gastric cancer with trastuzumab in recent years. …”
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    Correlation of Gli1 and HER2 expression in gastric cancer: Identification of novel target
  16. 1476
    “…In vitro analysis of the HER2-MUC1 construct confirmed the co-expression of MUC1 and HER2. …”
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    Immunogenicity of chimeric MUC1-HER2 vaccine against breast cancer in mice
  17. 1477
    “…BACKGROUND: The prognostic role of human epidermal growth factor receptor 2 (HER2) in ovarian cancer has been investigated in previous studies, but the results remain controversial. …”
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    The prognostic value of HER2 in ovarian cancer: A meta-analysis of observational studies
  18. 1478
    “…Overexpression of human epidermal growth factor receptor-2 (HER2) occurs in 20–30% of invasive breast cancers. …”
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    Virus-like particle display of HER2 induces potent anti-cancer responses
  19. 1479
    “…We also show that such inhibitors heighten efficacy of our nanobiologics on naïve tumors by augmenting HER3 expression. This approach takes advantage of a current clinical problem (i.e. resistance to growth factor inhibition) and uses it to make tumors more susceptible to HER3 nanobiologic treatment. …”
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    Resistance to receptor-blocking therapies primes tumors as targets for HER3-homing nanobiologics
  20. 1480
    “…HER2 transmembrane receptor is an important target in immunotherapy treatment of breast and gastroesophageal cancer. …”
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    Evaluation of HER2-specific peptide ligand for its employment as radiolabeled imaging probe
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