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Mostrando 1 - 20 Resultados de 775 Para Buscar '"Hergé"', tiempo de consulta: 0.33s Limitar resultados
  1. 1
    por Hergé, 1907-1983, Hergé, 1907-1983
    Publicado 1943
    Libro
    Les aventures de Tintin /
  2. 2
    por Hergé, 1907-1983, Hergé, 1907-1983
    Publicado 1968
    Libro
    Las aventuras de Tintin /
  3. 3
    por Goddin, Philippe
    Publicado 1992
    Materias: “…Hergé, 1907-1983.…”
    Libro
    Hergé y los bigotudos : la novela de una aventura
  4. 4
    por Islas, León D.
    Publicado 2013
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    The electric heart of hERG
  5. 5
    “…A recent open channel cryo-EM structure of hERG should greatly advance understanding of the molecular basis of hERG channelopathies and drug-induced LQTS. …”
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    An Update on the Structure of hERG
  6. 6
    “…The HERG-like channels opened rapidly on hyperpolarization from 0 mV, and then decayed slowly into an absorbing closed state. …”
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    HERG-like K(+) Channels in Microglia
  7. 7
    “…Two isoforms, hERG1a and hERG1b, associate to form the potassium current I(K)(r) in cardiomyocytes. …”
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    The N-linker region of hERG1a upregulates hERG1b potassium channels
  8. 8
    “…Cardiac hERG channels comprise two primary isoforms: hERG1a, which has a regulatory N-terminal Per-Arnt-Sim (PAS) domain, and hERG1b, which does not. …”
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    hERG1a N-terminal eag domain–containing polypeptides regulate homomeric hERG1b and heteromeric hERG1a/hERG1b channels: A possible mechanism for long QT syndrome
  9. 9
    “…Whole‐cell measurements of hERG current (I(hERG)) were made at 37°C from HEK 293 cells expressing wild‐type (WT) or hERG(T) channels. …”
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    Electrophysiological characterization of the modified hERG(T) potassium channel used to obtain the first cryo‐EM hERG structure
  10. 10
    por Guidelli, Rolando
    Publicado 2023
    “…The K(+) outward current of hERG contributes to the repolarization of the cardiac action potential. …”
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    An Insight into the Potassium Currents of hERG and Their Simulation
  11. 11
    “…Following inhibition of channel insertion into the cell membrane by brefeldin A (5 µM) the decay of current was similar in oocytes expressing HERG together with ß-catenin to oocytes expressing HERG alone. …”
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    Stimulation of HERG Channel Activity by β-catenin
  12. 12
    “…The results imply their stereospecific block effect on the hERG channel. However, F656C-hERG reversed this stereoselectivity. …”
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    Stereoselective Blockage of Quinidine and Quinine in the hERG Channel and the Effect of Their Rescue Potency on Drug-Induced hERG Trafficking Defect
  13. 13
    “…Cells were seeded on different substrates known to stimulate β1 integrins, such as fibronectin (FN) for HEK-hERG1 and laminin (LMN) for SH-SY5Y. In HEK cells stably overexpressing hERG1, we observed a hERG1 current density increase accompanied by V(rest) hyperpolarization after cell seeding onto FN. …”
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    The Interaction between hERG1 and β1 Integrins Modulates hERG1 Current in Different Pathological Cell Models
  14. 14
    “…HERG (human ether-à-go-go-related gene) encodes channels responsible for the cardiac rapid delayed rectifier potassium current, I(Kr). …”
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    Inhibition of the HERG potassium channel by the tricyclic antidepressant doxepin
  15. 15
    por Gang, Hongying, Zhang, Shetuan
    Publicado 2006
    “…Whereas hERG channels are highly selective for K(+), we have found that inactivated hERG channels allow Na(+) to permeate in the absence of K(+). …”
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    Na(+) Permeation and Block of hERG Potassium Channels
  16. 16
    “…A simple kinetic model is presented to explain the gating of a HERG-like voltage-gated K(+) conductance described in the accompanying paper (Zhou, W., F.S. …”
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    Idiosyncratic Gating of HERG-like K(+) Channels in Microglia
  17. 17
    “…Most of these drugs are known to interfere with the human ether à-gogo related gene 1 (hERG1) channel, whose current is one of the main determinants of action potential duration. …”
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    Stereoselective Inhibition of the hERG1 Potassium Channel
  18. 18
    por Cheng, Yen May, Claydon, Tom W.
    Publicado 2012
    “…Constraints upon hERG voltage sensor movement may result from loose packing of the S4 helices and additional intra-voltage sensor counter-charge interactions. …”
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    Voltage-Dependent Gating of hERG Potassium Channels
  19. 19
    “…EXPERIMENTAL APPROACH: HEK293 cells stably expressing hERG, K(IR)2.1 or Kv7.1/minK were studied using the patch clamp technique. …”
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    Long-Chain Acylcarnitines Regulate the hERG Channel
  20. 20
    “…The inward rectifier voltage-gated potassium channel hERG is of primary importance for the regulation of the membrane potential of cardiomyocytes. …”
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    Ion Conduction through the hERG Potassium Channel
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