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  1. 41
    por Grandi, Nicole, Tramontano, Enzo
    Publicado 2018
    “…Human endogenous retroviruses (HERVs) are relics of ancient infections accounting for about the 8% of our genome. …”
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    HERV Envelope Proteins: Physiological Role and Pathogenic Potential in Cancer and Autoimmunity
  2. 42
    “…Human Endogenous Retroviruses (HERVs) are accounting for 8% of the human genome. …”
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    Human Endogenous Retroviruses (HERVs): Shaping the Innate Immune Response in Cancers
  3. 43
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    Editorial: Unravelling the Role of HERVs in Cancer: Insights and New Targets for Therapy
  4. 44
    “…In addition, BPA exposure seems to upregulate the expression of HERVs, while a downregulation was observed after BPF and BPS treatments. …”
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    Bisphenols induce human genomic damage and modulate HERVs/env expression
  5. 45
    “…Herpesviruses can activate HERVs, and HERVs are activated in MS patients. RESULTS: Using flow cytometry, we have analyzed HERV-H Env and HERV-W Env epitope expression on the surface of PBMCs from MS patients with active and stable disease, and from control individuals. …”
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    B cells and monocytes from patients with active multiple sclerosis exhibit increased surface expression of both HERV-H Env and HERV-W Env, accompanied by increased seroreactivity
  6. 46
    “…However enhanced expression of HERV-K accompanied by the emergence of anti-HERV-K-directed immune responses has been observed inter-alia in HIV-infected individuals and tumor patients. …”
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    Vaccination directed against the human endogenous retrovirus-K (HERV-K) gag protein slows HERV-K gag expressing cell growth in a murine model system
  7. 47
    “…Human endogenous retroviruses (HERVs) comprise nearly 8% of the human genome and are derived from ancient integrations of retroviruses into the germline. …”
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    Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K–specific inhibition
  8. 48
    por Bazin, Hervé, 1911-1996
    Publicado 1950
    Libro
    La mort du petit cheval, roman /
  9. 49
    “…BACKGROUND: The cell-surface attachment protein (Env) of the HERV-K(HML-2) lineage of endogenous retroviruses is a potentially attractive tumour-associated antigen for anti-cancer immunotherapy. …”
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    Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines
  10. 50
    por Saba, A.
    Publicado 2007
    “…Herve Borel (CEA Saclay), responsible for the tracking chambers of the ALICE Moun spectrometer…”
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    Herve Borel (CEA Saclay), responsible for the tracking chambers of the ALICE Moun spectrometer
  11. 51
    “…Real-time quantitative PCR was used to detect the transcript levels of HERV-K(HML-2) gag, pol, and env in colorectal cancer to systematically investigate the connection between HERV-K(HML-2) and colorectal cancer. …”
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    Identification of differentially expressed HERV-K(HML-2) loci in colorectal cancer
  12. 52
    por Costa, Bárbara, Vale, Nuno
    Publicado 2023
    “…This review investigates the intricate role of human endogenous retroviruses (HERVs) in cancer development and progression, explicitly focusing on HERV-K (HML-2). …”
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    Exploring HERV-K (HML-2) Influence in Cancer and Prospects for Therapeutic Interventions
  13. 53
    “…A number of loci of the HERV-K(HML-2) family are evolutionarily much younger. …”
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    Expression pattern analysis of transcribed HERV sequences is complicated by ex vivo recombination
  14. 54
    “…Transcripts and proteins of at least three HERV groups, HERV-W, ERV9 and HERV-K(HML-2) have been detected repeatedly in brain samples or cerebrospinal fluid of patients with schizophrenia suggesting that alterations in HERV activity may play a role in etiopathogenesis. …”
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    Influence of Antipsychotic Drugs on Human Endogenous Retrovirus (HERV) Transcription in Brain Cells
  15. 55
    “…In addition, we find sequence variation in the chromosome 4 HERV that makes one allele more like the chromosome 18 HERV. …”
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    A recurrent translocation is mediated by homologous recombination between HERV-H elements
  16. 56
    “…BACKGROUND: Human endogenous retroviruses (HERVs) are suspected to play a role in the development of multiple sclerosis (MS). …”
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    No additional copies of HERV-Fc1 in the germ line of multiple sclerosis patients
  17. 57
    “…Human endogenous retroviruses (HERV) sequences account for about 8% of the human genome. …”
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    Human-Specific HERV-K Insertion Causes Genomic Variations in the Human Genome
  18. 58
    “…BACKGROUND: The human endogenous retrovirus K (HERV-K) has been acquired by the genome of human ancestors million years ago. …”
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    Expression-analysis of the human endogenous retrovirus HERV-K in human astrocytic tumors
  19. 59
    “…The First International Scientific Conference on Human Endogenous Retroviruses (HERVs) and Disease, Lyon-France, May 26-27(th) 2015, brought together scientific and medical specialists from around the world investigating the involvement of human endogenous retroviruses (HERVs) in complex human diseases.…”
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    First international workshop on human endogenous retroviruses and diseases, HERVs & disease 2015
  20. 60
    “…Though most human endogenous retroviruses (HERVs) are thought to be irrelevant to our biology notable exceptions include members of the HERV-H family that are necessary for the correct functioning of stem cells. …”
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    Phylogenetic Analysis Reveals That ERVs "Die Young" but HERV-H Is Unusually Conserved
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