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  1. 6521
    “…KZFP genes are preferentially encoded nearby the activated HERVs in tumors and transcriptionally regulated by these adjacent HERVs. …”
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    Endogenous retroviruses drive KRAB zinc-finger protein family expression for tumor suppression
  2. 6522
    “…Previous genetic and functional studies have implicated the human endogenous retrovirus K (HERV-K) dUTPase located within the PSORS1 locus in the MHC region as a candidate psoriasis gene. …”
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    Protective Effect of Human Endogenous Retrovirus K dUTPase Variants on Psoriasis Susceptibility
  3. 6523
    “…Human endogenous retroviruses (HERV) are largely distributed within the human genome with hundreds of thousands of elements. …”
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    Human endogenous retroviruses and chosen disease parameters in morphea
  4. 6524
    “…PBRM1 mutations were consistently associated with increased hERV expression in primary tumors. In vitro silencing of PBRM1, HIF1A, and HIF2A followed by RNA sequencing was performed in UMRC2 cells, confirming that PBRM1 regulates hERVs in a HIF1α- and HIF2α-dependent manner and that hERVs of the HERVERI superfamily are enriched in PBRM1-regulated hERVs. …”
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    PBRM1 Inactivation Promotes Upregulation of Human Endogenous Retroviruses in a HIF-Dependent Manner
  5. 6525
    “…Three HERV families have been associated with MS: HERV-H, HERV-K, and HERV-W. …”
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    Multiple Sclerosis between Genetics and Infections: Human Endogenous Retroviruses in Monocytes and Macrophages
  6. 6526
    “…We observed that baculoviruses with HERV envelopes (AcHERV) exhibited specifically higher gene transfer efficiency in human cells compared to the wild-type baculovirus vector. …”
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    The Safe Baculovirus-Based PrM/E DNA Vaccine Protected Fetuses against Zika Virus in A129 Mice
  7. 6527
    “…Plasma anti-env responses of HERV-K, -H and -W were tested with indirect ELISA. …”
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    Antihuman Endogenous Retrovirus Immune Response and Adaptive Dysfunction in Autism
  8. 6528
    “…RESULTS: Transient expression of the 475 amino acid Xq22.3 HERV-W env ORF produced an N-terminally truncated HERV-W Env protein, as detected by the monoclonal anti-HERV-W Env antibodies 6A2B2 and 13H5A5. …”
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    An N-terminally truncated envelope protein encoded by a human endogenous retrovirus W locus on chromosome Xq22.3
  9. 6529
    por Liang, Qiaoyi, Ding, Jiayi, Zheng, Shu
    Publicado 2009
    “…In this study, an H family HERV (HERV-H)-related gene was identified and characterized. …”
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    Identification and detection of a novel human endogenous retrovirus-related gene, and structural characterization of its related elements
  10. 6530
    por Giménez-Orenga, Karen, Oltra, Elisa
    Publicado 2021
    “…Human endogenous retroviruses (HERVs) are ancient retroviral DNA sequences established into germline. …”
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    Human Endogenous Retrovirus as Therapeutic Targets in Neurologic Disease
  11. 6531
    por Agoni, Lorenzo
    Publicado 2022
    “…Human endogenous retroviruses (HERVs) are transcribed in many cancer types, including head and neck cancer. …”
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    Alternative and aberrant splicing of human endogenous retroviruses in cancer. What about head and neck? —A mini review
  12. 6532
    “…BACKGROUND: Aberrant expression of human endogenous retrovirus (HERV) elements in the W family has previously been associated with schizophrenia, multiple sclerosis and preeclampsia. …”
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    Transactivation of elements in the human endogenous retrovirus W family by viral infection
  13. 6533
    “…The HERV envelope-coated, nonreplicable, baculovirus-based DNA vaccine, encoding HPV16L1, -18L1 and -58L1 (AcHERV-triHPV), was constructed and sublingually administered to mice without adjuvant. …”
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    Sublingual Immunization of Trivalent Human Papillomavirus DNA Vaccine in Baculovirus Nanovector for Protection against Vaginal Challenge
  14. 6534
    “…The expression of human endogenous retroviruses (HERVs) has been associated with Multiple Sclerosis (MS). …”
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    Do Antiretroviral Drugs Protect From Multiple Sclerosis by Inhibiting Expression of MS-Associated Retrovirus?
  15. 6535
    “…Human endogenous retroviruses (HERVs) are originated from ancient exogenous retroviruses, which infected human germ line cells millions of years ago. …”
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    Human Endogenous Retroviruses: Friends and Foes in Urology Clinics
  16. 6536
    “…The toxicity of HERV-derived RNAs and proteins for neuronal cells has been demonstrated. …”
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    Endogenous Retroviruses in Nervous System Disorders
  17. 6537
    “…Human endogenous retrovirus type W (HERV-W) is expressed in various cancers. We previously developed an adenovirus-vectored cancer vaccine targeting HERV-W by encoding an assembled HERV-W group-specific antigen sequence and the HERV-W envelope sequence Syncytin-1. …”
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    The Insertion of an Evolutionary Lost Four-Amino-Acid Cytoplasmic Tail Peptide into a Syncytin-1 Vaccine Increases T- and B-Cell Responses in Mice
  18. 6538
    “…Most HERVs are ancient and invaded our genome at least 25 million years ago, except for the evolutionary young HERV-K group. …”
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    Identification of endogenous retroviral reading frames in the human genome
  19. 6539
    por Hurst, Tara P., Magiorkinis, Gkikas
    Publicado 2017
    “…We will discuss some of the common epigenetic mechanisms and how they affect HERV expression, providing detailed discussions of HERVs in stem cell, placenta and cancer biology.…”
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    Epigenetic Control of Human Endogenous Retrovirus Expression: Focus on Regulation of Long-Terminal Repeats (LTRs)
  20. 6540
    “…Human endogenous retroviruses (HERVs) are the remains of ancient retroviruses that invaded our ancestors’ germline cell and were integrated into the genome. …”
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    Transcriptome Analyses Implicate Endogenous Retroviruses Involved in the Host Antiviral Immune System through the Interferon Pathway
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