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Mostrando 81 - 100 Resultados de 7,384 Para Buscar '"Hervé This"', tiempo de consulta: 0.52s Limitar resultados
  1. 81
    “…The human endogenous retrovirus-K (HERV-K) and TAR DNA-binding protein 43 (TDP-43) have been associated with the pathophysiology of amyotrophic lateral sclerosis (ALS). …”
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    TDP-43 and HERV-K Envelope-Specific Immunogenic Epitopes Are Recognized in ALS Patients
  2. 82
    “…HERVs are defective and do not produce infectious viral particles. …”
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    Syncytin, envelope protein of human endogenous retrovirus (HERV): no longer ‘fossil’ in human genome
  3. 83
    “…Human endogenous retroviruses (HERVs) make up a significant part of our genome. …”
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    Not all viruses cause disease: HERV-K(HML-2) in healthy human tissues
  4. 84
    “…Among HERVs, the most characterized elements belong to the beta-like superfamily HERV-K, comprising 10 groups (HML1-10) with HML2 being the most recent and studied one. …”
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    Identification, comprehensive characterization, and comparative genomics of the HERV-K(HML8) integrations in the human genome
  5. 85
    “…Conversely, SNPs around one retroviral locus, HERV-Fc1, showed a highly significant association with disease. …”
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    The Etiology of Multiple Sclerosis: Genetic Evidence for the Involvement of the Human Endogenous Retrovirus HERV-Fc1
  6. 86
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    Expression of HERV-H/W env epitopes on PBMCs from MS patients with active disease
  7. 87
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    Involvement of the endogenous retroviral locus HERV-Fc1 on the human X-chromosome in multiple sclerosis
  8. 88
    “…We established a characteristic HERV signature consisting of six ubiquitously active HERV subgroups (E4-1, HERV-Rb, ERV9, HERV-K-T47D, NMWV3, HERV-KC4). …”
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    HERV-E-Mediated Modulation of PLA2G4A Transcription in Urothelial Carcinoma
  9. 89
    “…CONCLUSION: The developmental regulation of HERV-H expression, the association of HERV-H with binding sites for pluripotency transcription factors, and the extremely high levels of HERV-H RNA in human ES cells suggest that HERV-H contributes to pluripotency in human cells. …”
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    HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency
  10. 90
    “…Recent studies suggested a role for the human endogenous retrovirus (HERV) group HERV-K(HML-2) in melanoma because of upregulated transcription and expression of HERV-K(HML-2)-encoded proteins. …”
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    Transcriptional Profiling of Human Endogenous Retrovirus Group HERV-K(HML-2) Loci in Melanoma
  11. 91
    “…Multiple Sclerosis Associated Retrovirus (MSRV) is a member of HERV-W, a multicopy human endogenous retroviral family repeatedly implicated in MS pathogenesis. …”
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    Online Artículo Texto
    HERV-W polymorphism in chromosome X is associated with multiple sclerosis risk and with differential expression of MSRV
  12. 92
    “…Some HERV loci still express proteins that have been associated with several pathologies including cancer(7-10). …”
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    Online Artículo Texto
    Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
  13. 93
    “…Roughly 8% of the human genome consists of about 400,000 LTR elements including human endogenous retrovirus (HERV) sequences. Mainly, the interplay between epigenetic and post-transcriptional mechanisms is thought to silence HERV expression in most physiological contexts. …”
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    Generation, Characterization and Application of Antibodies Directed against HERV-H Gag Protein in Colorectal Samples
  14. 94
    “…HERVs have been shown to generate RNAs that modulate host gene expression. …”
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    The intron-enriched HERV-K(HML-10) family suppresses apoptosis, an indicator of malignant transformation
  15. 95
    “…Herein, we investigated the correlation between HERV-K and the CD133+ melanoma cells during microenvironmental modifications. …”
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    HERV-K activation is strictly required to sustain CD133+ melanoma cells with stemness features
  16. 96
    “…HERV-K and HERV-F expression was assessed by quantitative real-time PCR in 120 patient specimens. …”
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    Elevated HERV-K Expression in Soft Tissue Sarcoma Is Associated with Worsened Relapse-Free Survival
  17. 97
    “…Our data provide innovative insights into the mechanisms of HERV-K transactivation contributing to viral oncogenesis, which may represent a promising target for KS treatment.…”
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    Online Artículo Texto
    Transactivation of human endogenous retrovirus K (HERV-K) by KSHV promotes Kaposi’s Sarcoma development
  18. 98
    “…It has been suggested that several risk factors, either considered as external or internal, play a critical role in the pathogenesis of breast cancer, which among them, HERV-k, has the most fundamental role. In the present study, we aimed to evaluate the role of HERV-k env, gag, rec, np9 expressions in breast cancer progression. …”
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    Evaluating the expression level of HERV-K env, np9, rec and gag in breast tissue
  19. 99
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    Effect of hydroxychloroquine and azithromycin on the viral clearance of SARS-CoV-2: response to Hervé Seligmann
  20. 100
    por Garcia-Montojo, Marta, Nath, Avindra
    Publicado 2021
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    Online Artículo Texto
    HERV-W envelope expression in blood leukocytes as a marker of disease severity of COVID-19
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