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161por Arru, Giannina, Sechi, Elia, Mariotto, Sara, Farinazzo, Alessia, Mancinelli, Chiara, Alberti, Daniela, Ferrari, Sergio, Gajofatto, Alberto, Capra, Ruggero, Monaco, Salvatore, Deiana, Giovanni A, Caggiu, Elisa, Mameli, Giuseppe, Sechi, Leonardo A, Sechi, Gian Pietro“…An indirect ELISA was set up to detect specific Abs against HERV-W env-su peptides. RESULTS: Our data showed that two antigenic peptides, particularly HERV-Wenv(93–108) and HERV-Wenv(248–262,) were statistically significantly present only in serum of MS compared to NMOSD and HCs. …”
Publicado 2017
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162por Mayer, Jens, Harz, Christian, Sanchez, Laura, Pereira, Gavin C., Maldener, Esther, Heras, Sara R., Ostrow, Lyle W., Ravits, John, Batra, Ranjan, Meese, Eckart, García-Pérez, Jose Luis, Goodier, John L.“…The human endogenous retrovirus multi-copy HERV-K(HML-2) group was recently reported to potentially contribute to neurodegeneration and disease pathogenesis in ALS because of transcriptional upregulation and toxic effects of HML-2 Envelope (Env) protein. …”
Publicado 2018
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163“…Human Endogenous retroviruses (HERVs) are remnants of ancient retroviral infections that represent a large fraction of our genome. …”
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164por Weber, Melanie, Padmanabhan Nair, Vidya, Bauer, Tanja, Sprinzl, Martin F., Protzer, Ulrike, Vincendeau, Michelle“…Several clinical parameters specifying poor liver function are positively correlated with HERV-K(HML-2) expression. Of note, patients without a sustained viral clearance showed a drastic increase in HERV-K(HML-2) transcript levels. …”
Publicado 2021
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165“…Specifically, we described the HERV transcriptome in PBMCs and identified HERV and MaLR loci differentially expressed after the 2nd, 3rd, and 4th inactivated vaccine administrations. …”
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166por Li, Xi, Guo, Yaolin, Li, Hanping, Huang, Xiaofeng, Pei, Zhichao, Wang, Xiaolin, Liu, Yongjian, Jia, Lei, Li, Tianyi, Bao, Zuoyi, Wang, Xiaorui, Han, Leilei, Han, Jingwan, Li, Jingyun, Li, Lin“…For example, HIV infection can cause abnormal activation of HERVs, and under different infection conditions, HERV expression may be different. …”
Publicado 2021
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167por Tamouza, Ryad, Meyer, Urs, Foiselle, Marianne, Richard, Jean-Romain, Wu, Ching-lien, Boukouaci, Wahid, Le Corvoisier, Philippe, Barrau, Caroline, Lucas, Alexandre, Perron, Hervé, Leboyer, MarionEnlace del recurso
Publicado 2021
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168por Göttle, Peter, Schichel, Kira, Reiche, Laura, Werner, Luisa, Zink, Annika, Prigione, Alessandro, Küry, Patrick“…Our study, therefore, provides novel insights into possible means to overcome myelination deficits associated with HERV-W ENV-mediated myelin deficits.…”
Publicado 2021
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170“…Around 8% of the human genome comprises Human Endogenous Retroviruses (HERVs) acquired over primate evolution. Some are specific to primates such as HERV-K, consisting of 10 HML subtypes and including the most recently acquired elements. …”
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173por Nellåker, Christoffer, Li, Fang, Uhrzander, Fredrik, Tyrcha, Joanna, Karlsson, Håkan“…BACKGROUND: Human endogenous retroviruses (HERV) constitute approximately 8% of the human genome and have long been considered "junk". …”
Publicado 2009
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174por Hohn, Oliver, Hanke, Kirsten, Lausch, Veronika, Zimmermann, Anja, Mostafa, Saeed, Bannert, Norbert“…The HERV-K(HML-2) family contains the most recently integrated and best preserved endogenized proviral sequences in the human genome. …”
Publicado 2014
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175por Hurst, Tara, Pace, Matthew, Katzourakis, Aris, Phillips, Rodney, Klenerman, Paul, Frater, John, Magiorkinis, Gkikas“…We examined the expression of HERV-K (HML-2) env and pol, as well as the co-opted genes HERV-W env (syncytin-1), HERV-FRD env (syncytin-2), in these cell lines. …”
Publicado 2016
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176por Machnik, Grzegorz, Skudrzyk, Estera, Bułdak, Łukasz, Ruczyński, Jarosław, Kozłowska, Agnieszka, Mucha, Piotr, Rekowski, Piotr, Szkróbka, Witold, Basiak, Marcin, Bołdys, Aleksandra, Sławska, Helena, Okopień, Bogusław“…We developed a peptide nucleic acid (PNA) strand invasion technique for the differentiation between multiple sclerosis-associated retrovirus (MSRV) and ERVWE1 sequences, both molecularly similar, belonging to the human endogenous retrovirus HERV-W family. We have found that this method may support the PCR technique in screening for minor alleles which, in certain conditions, may be undetected by the standard PCR technique. …”
Publicado 2018
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177por Charvet, Benjamin, Brunel, Joanna, Pierquin, Justine, Iampietro, Mathieu, Decimo, Didier, Queruel, Nelly, Lucas, Alexandre, Encabo-Berzosa, María del Mar, Arenaz, Izaskun, Marmolejo, Tania Perez, Gonzalez, Arturo Ivan, Maldonado, Armando Castorena, Mathieu, Cyrille, Küry, Patrick, Flores-Rivera, Jose, Torres-Ruiz, Fernanda, Avila-Rios, Santiago, Salgado Montes de Oca, Gonzalo, Schoorlemmer, Jon, Perron, Hervé, Horvat, Branka“…We show here that in vitro exposure to SARS-CoV-2 activates the expression of the human endogenous retrovirus (HERV) HERV-W proinflammatory envelope protein (ENV) in peripheral blood mononuclear cells from a subset of healthy donors, in ACE2 receptor and infection-independent manner. …”
Publicado 2023
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178por Skandorff, Isabella, Ragonnaud, Emeline, Gille, Jasmin, Andersson, Anne-Marie, Schrödel, Silke, Duvnjak, Lara, Turner, Louise, Thirion, Christian, Wagner, Ralf, Holst, Peter Johannes“…Expression of human endogenous retrovirus type W (HERV-W) has been linked to cancer, making HERV-W antigens potential targets for therapeutic cancer vaccines. …”
Publicado 2023
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179por Ruggieri, Alessia, Maldener, Esther, Sauter, Marlies, Mueller-Lantzsch, Nikolaus, Meese, Eckart, Fackler, Oliver T, Mayer, Jens“…BACKGROUND: The human endogenous retrovirus HERV-K(HML-2) family is associated with testicular germ cell tumors (GCT). …”
Publicado 2009
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180por Hansen, Bettina, Oturai, Annette B., Harbo, Hanne F., Celius, Elisabeth G., Nissen, Kari K., Laska, Magdalena J., Søndergaard, Helle B., Petersen, Thor, Nexø, Bjørn A.“…We have previously described the occurrence of multiple sclerosis (MS) to be associated with human endogenous retroviruses, specifically the X-linked viral locus HERV-Fc1. The aim of this study was to investigate a possible association of the HERV-Fc1 locus with subtypes of MS. …”
Publicado 2011
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