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  1. 341
    “…However, the absence of polarizability and the high C–H bond strength are considered to be the main drawbacks that limit its oxidation by traditional catalytic converters. …”
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    Natural clay-supported palladium catalysts for methane oxidation reaction: effect of alloying
  2. 342
    “…RESULTS: Multivariate regression analysis revealed that the age and ISS scores were the independent risk factors, while the GCS score had protective effects on in-hospital survival. The high C-index and area under the curve (AUC) of the ROC curve confirmed reasonable discrimination for the multivariate analysis and the nomogram prediction model. …”
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    Development of a Nomogram Model to Predict in-Hospital Survival in Patients with Multiple Trauma
  3. 343
    “…This is particularly relevant for B-cell lymphomas, characterized by a high level of constitutive stress due to high c-Myc expression. In this study, we found that IRE1α/XBP1 axis inhibition exerted a stronger cytotoxic effect compared to the inhibition of the other two UPR sensors, namely PERK and ATF6, in Burkitt lymphoma (BL) cells, in correlation with c-Myc downregulation. …”
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    Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas
  4. 344
    “…Surprisingly, further experimental assays reveal that the BAMBI(high)MFGE8(high) C1 subgroup has a unique phenotype, distinct transcriptomic profile, and limited adipogenic differentiation potential but compromised immunosuppressive activity in vitro and in vivo in lupus mice. …”
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    Dissecting Heterogeneity Reveals a Unique BAMBI(high)MFGE8(high) Subpopulation of Human UC‐MSCs
  5. 345
    “…Aldesleukin is rapidly cleared requiring frequent dosing, resulting in high C(max) likely potentiating toxicity. Thus, IL-2 cancer immunotherapy has two critical drawbacks: potent activation of undesired IL-2Rα(+) cells and suboptimal pharmacokinetics with high C(max) and short half-life. …”
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    TransCon IL-2 β/γ: a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 variant with improved pharmacokinetics and potent activation of cytotoxic immune cells for the treatment of cancer
  6. 346
    “…[Figure: see text] Low (A), Medium (B) and High (C) anti-SARS-CoV-2 IgG (WHO Standards) show different neutralising capacities against WT (D614G) SARS-CoV-2 and variants Beta and Omicron, measured using Micro-NT on Vero-E6-TMPRSS2 cells. …”
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    1057. Development of a Flow Cytometry-Based Micro-Neutralisation Assay to Evaluate Humoral Immunity Against SARS-CoV-2 Variants of Concern in Vaccine Trials
  7. 347
    “…The opportunity for diagnosis was low C0 and high C5-OH acylcarnitine levels in their newborn. …”
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    A Study of Maternal Patients Diagnosed with Inborn Errors of Metabolism Due to Positive Newborn Mass Screening in Their Newborns
  8. 348
    por Lakhotia, Subhash C.
    Publicado 2023
    “…Consequently, persistence of the new-found ‘solution/s’ often appear bizarre, uneconomic, and therefore, paradoxical to human logic. The unexpectedly high c-values in diverse organisms are irreversible evolutionary accidents that persisted, and the additional DNA often got repurposed over the evolutionary time scale. …”
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    C-value paradox: Genesis in misconception that natural selection follows anthropocentric parameters of ‘economy’ and ‘optimum’
  9. 349
    “…African American recipients had a lower incidence of BKPyV infection (12% vs. 39%), yet a higher incidence was observed in those with high cPRA (50% vs. 14%). Most CMV and/or BKPyV infections occurred within the first six months post-transplant (54%). …”
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    Risk Factors for CMV and BK Infections in an Elderly Veteran Population Following Kidney Transplantation: Implications for Immunosuppression Induction and Management
  10. 350
    Publicado 1994
    “…We find that a rise in intracellular cAMP ([cAMP]i) induces pigment dispersion, and that this dispersive stimulus can be overridden by an aggregation stimulus, suggesting that both high [cAMP]i and low [Ca2+]i are necessary to produce pigment dispersion in erythrophores.…”
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    Intracellular calcium and cAMP regulate directional pigment movements in teleost erythrophores
  11. 351
    “…Six of the studied children with high cTnT levels (54.5%) died within 21 days of treatment while only one case (2.9%) with normal level of cTnT died within the same period. …”
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    Myocardial dysfunction in malnourished children
  12. 352
    “…In Pde6b mouse models of retinitis pigmentosa (RP), photoreceptor death is preceded by abnormally high cGMP and Ca(2+) levels, likely because of continued synthesis of cGMP by guanylate cyclases and unregulated influx of Ca(2+) to toxic levels through CNG channels. …”
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    shRNA knockdown of guanylate cyclase 2e or cyclic nucleotide gated channel alpha 1 increases photoreceptor survival in a cGMP phosphodiesterase mouse model of retinitis pigmentosa
  13. 353
    “…The latter was manifested by high C/N ratio in L. pumila plants.…”
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    Effects of Nitrogen Fertilization on Synthesis of Primary and Secondary Metabolites in Three Varieties of Kacip Fatimah (Labisia Pumila Blume)
  14. 354
    “…XRD pattern of the ZnO thin film shows that it has a high c-axis-preferring orientation, which is confirmed by a FE-SEM cross-sectional image of the film. …”
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    Preparation and characterization of ZnO microcantilever for nanoactuation
  15. 355
    “…Only better aerobic capacity was associated with lower frequency of high C-reactive protein when adjusted to diabetes and gender in a logistic regression model. …”
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    Inflammation, Diabetes, and Chronic Kidney Disease: Role of Aerobic Capacity
  16. 356
    por Yu, Ke, Zhang, Tong
    Publicado 2012
    “…Specially, ammonia monooxygenase and hydroxylamine oxidase demonstrated the high cDNA/DNA ratios in the present study, indicating strong nitrification activity. …”
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    Metagenomic and Metatranscriptomic Analysis of Microbial Community Structure and Gene Expression of Activated Sludge
  17. 357
    “…The most affected genome regions tend to correlate with high C + G content, however this relationship is complex and does not explain why the direction and magnitude of effects varies considerably between samples. …”
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    A mechanistic basis for amplification differences between samples and between genome regions
  18. 358
    “…The overall response to 8% CO(2) in Cyanothece 51142 involves different strategies, to compensate for the high C/N ratio during both phases of the diurnal cycle. …”
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    Carbon Availability Affects Diurnally Controlled Processes and Cell Morphology of Cyanothece 51142
  19. 359
    “…A significant difference in the cED among injury mechanisms was seen (p<0.001) and patients with traffic accidents and fall down injuries showed relatively high cED values. Hence, to reduce the cED of injury patients, an age-, sex- and injury mechanism-specific dose reduction strategy should be considered.…”
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    Diagnostic Radiation Exposure of Injury Patients in the Emergency Department: A Cross-Sectional Large Scaled Study
  20. 360
    “…This study compared the haplotype structure and expression profile in skeletal muscle and brain of inherently high- (C57L/J) and low- (C3H/HeJ) active mice. Expression of nine candidate genes [Actn2, Actn3, Casq1, Drd2, Lepr, Mc4r, Mstn, Papss2, and Glut4 (a.k.a. …”
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    Differential Gene Expression in High- and Low-Active Inbred Mice
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