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801“…High APACHE II score (aOR 1.112, 95% CI 1.014–1.219; p < 0.05), high C-reactive protein (aOR 1.011; 95% CI 1.004–1.019; p < 0.01) and carbapenem usage in past 90 days (aOR 3.259; 95% CI 1.105–9.609; p < 0.05) were independent risk factors of severe CDI. …”
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802por Utsunomiya, Atae“…Based on the analysis of patients with aggressive ATL, including those who received transplants, we identified five prognostic factors for poor outcomes: acute-type ATL, poor performance status, high soluble interleukin-2 receptor levels, hypercalcemia, and high C-reactive protein level. Next, we developed a new prognostic index: the modified ATL-PI. …”
Publicado 2019
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803“…Laboratory tests revealed a high neutrophil count (15,000/μl) and a high C-reactive protein (CRP) level (46.35 mg/dl) without any other abnormalities. …”
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804por Gymnopoulos, Marco, Betancourt, Oscar, Blot, Vincent, Fujita, Ryo, Galvan, Diana, Lieuw, Vincent, Nguyen, Sophie, Snedden, Jeanette, Stewart, Christine, Villicana, Jose, Wojciak, Jon, Wong, Eley, Pardo, Raul, Patel, Neki, D’Hooge, Francois, Vijayakrishnan, Balakumar, Barry, Conor, Hartley, John A., Howard, Philip W., Newman, Roland, Coronella, Julia“…The potency of our cMet ADC is independent of MET gene copy number, and its antitumor activity was high not only in high cMet‐expressing cell lines but also in medium‐to‐low cMet cell lines (40 000–90 000 cMet/cell) in which a cMet ADC with tubulin inhibitor payload was considerably less potent. …”
Publicado 2019
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805por McDonald, Brandon W., Perkins, Troi, Dunn, Robert R., McDonald, Jennifer, Cole, Holly, Feranec, Robert S., Kays, Roland“…Our results question the general assumption that anthropogenic foods always have high C isotope values, because of the high variability we documented within one product type (cat food) and between countries (US vs. …”
Publicado 2020
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806por Adachi, Yuichi, Tamiya, Akihiro, Taniguchi, Yoshihiko, Enomoto, Takatoshi, Azuma, Kouji, Kouno, Shunichi, Inagaki, Yuji, Saijo, Nobuhiko, Okishio, Kyoichi, Atagi, Shinji“…Multivariate analysis showed that never smoking (hazard ratio [HR], 1.77; 95% confidence interval [CI], 1.15‐2.75), high C‐reactive protein (CRP) (HR, 1.39; 95% CI, 1.00‐1.93), liver metastasis (HR, 1.95; 95% CI, 1.24‐3.07), pleural effusion (HR, 1.45; 95% CI, 1.06‐2.00), and steroid use (HR, 2.85; 95% CI, 1.65‐4.94) were associated with significantly shorter PFS in patients with good PS. …”
Publicado 2019
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807por Shahulhameed, Shahna, Vishwakarma, Sushma, Chhablani, Jay, Tyagi, Mudit, Pappuru, Rajeev R., Jakati, Saumya, Chakrabarti, Subhabrata, Kaur, Inderjeet“…Further, a significantly high C3 deposition in the capillary wall along with thickening of basement membranes and co-localization of CFH expression with CD11b(+ve) activated microglial cells in diabetic retina suggested microglia as a source of CFH in diabetic retina. …”
Publicado 2020
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808“…GuHCl is characterized by low C (m) (~1 M), while urea is characterized by high C (m) (~3 M). The fully unfolded states were reached at 2 M GuHCl and 4 M urea concentration, respectively. …”
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809por Banerjee, Debasish, Popoola, Joyce, Shah, Sapna, Ster, Irina Chis, Quan, Virginia, Phanish, Mysore“…Other common clinical features included hypoxia, chest crepitation, lymphopenia and high C-reactive protein. Very high D dimer, ferritin and troponin levels occurred in severe cases and likely prognostic. …”
Publicado 2020
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810por Hong, Ming-Yuan, Hsieh, Chih-Chia, Yang, Chao-Yung, Lee, Chung-Hsun, Ko, Wen-Chien, Lee, Ching-Chi“…Besides the presence of magA (ie, capsular serotype K1) and the HMV-phenotype, five clinical predictors were significantly associated with abscesses in a multivariate analysis: male gender, comorbidities with diabetes mellitus or neurological disorders, recent chemotherapy, and high c-reactive protein levels. Together, these predictors were used to calculate the CoKPB abscess score. …”
Publicado 2020
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811“…RESULTS: Based on three selected texture features, the radiomics signature showed high C-indexes of 0.782 (95%CI: 0.656–0.909) and 0.752 (95%CI, 0.614–0.891) in the two cohorts. …”
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812por Yoshida, Tatsuya, Ichikawa, Junya, Giuroiu, Iulia, Laino, Andressa S, Hao, Yuhan, Krogsgaard, Michelle, Vassallo, Melinda, Woods, David M, Stephen Hodi, F, Weber, Jeffrey“…BACKGROUND: High C reactive protein (CRP) levels have been reported to be associated with a poor clinical outcome in a number of malignancies and with programmed cell death protein 1 immune checkpoint blockade in patients with advanced cancer. …”
Publicado 2020
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813por Chen, Xiancheng, Cao, Ke, Wei, Yu, Qian, Yajun, Liang, Jing, Dong, Danjiang, Tang, Jian, Zhu, Zhanghua, Gu, Qin, Yu, Wenkui“…Laboratory data showed normal or slightly increased leucocytes, neutrophils, and procalcitonin but high C-reactive protein levels. Computed tomography revealed air-space consolidation and ground-glass opacity, which began in the upper lobe of one lung, and spread to both lungs, along with miliary, nodular, or consolidated shadows. …”
Publicado 2020
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814por Wei, Sung-Jen, Nguyen, Thinh H., Yang, In-Hyoung, Mook, Dustin G., Makena, Monish Ram, Verlekar, Dattesh, Hindle, Ashly, Martinez, Gloria M., Yang, Shengping, Shimada, Hiroyuki, Reynolds, C. Patrick, Kang, Min H.“…In conclusion, we demonstrated that high c-MYC expression independent of genomic amplification is associated with disease progression in neuroblastoma. …”
Publicado 2020
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815“…The median (interquartile range, IQR) duration to first detected AF was 11 (1–46), 6 (1–49), and 4 (1–24) in the population with low, intermediate, and high C(2)HEST score category, respectively (p = 0.03). …”
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816por Zuidema, Pieter A., Heinrich, Ingo, Rahman, Mizanur, Vlam, Mart, Zwartsenberg, Sophie A., van der Sleen, Peter“…At warmer sites, drought sensitivity increased with increasing c (a), as predicted, and hot years caused stronger growth reduction at high c (a). Overall, c (a) rise has significantly modified sensitivity of Toona stem growth to climatic variation, but these changes depended on mean climate. …”
Publicado 2020
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817por Di Bacco, Alessandra, Bahlis, Nizar J., Munshi, Nikhil C., Avet‐Loiseau, Hervé, Masszi, Tamás, Viterbo, Luísa, Pour, Ludek, Ganly, Peter, Cavo, Michele, Langer, Christian, Kumar, Shaji K., Rajkumar, S. Vincent, Keats, Jonathan J., Berg, Deborah, Lin, Jianchang, Li, Bin, Badola, Sunita, Shen, Lei, Zhang, Jacob, Esseltine, Dixie‐Lee, Luptakova, Katarina, van de Velde, Helgi, Richardson, Paul G., Moreau, Philippe“…RESULTS: The PFS benefit of IRd vs placebo‐Rd was greater in patients with tumors expressing high c‐MYC levels (median not reached vs 11.3 months; hazard ratio [HR] 0.42; 95% CI, 0.26, 0.66; P < .001) compared with in those expressing low c‐MYC levels (median 20.6 vs 16.6 months; HR 0.75; 95% CI, 0.42, 1.2). …”
Publicado 2020
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818por Vad, Csaba F., Schneider, Claudia, Lukić, Dunja, Horváth, Zsófia, Kainz, Martin J., Stibor, Herwig, Ptacnik, Robert“…Low lipid content and high C:P elemental ratio further supported the low nutritional value of the mixotroph. …”
Publicado 2020
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819por Wang, Longmian, Pang, Qingqing, Peng, Fuquan, Zhang, Aiguo, Zhou, Ying, Lian, Jianjun, Zhang, Yimin, Yang, Fei, Zhu, Yueming, Ding, Chengcheng, Zhu, Xiang, Li, Yiping, Cui, Yibin“…Molecular biological analysis revealed that during the stabilization period, a low C/N ratio remarkably promoted diversities of ammonia-oxidizing archaea (AOA) and ammonia-oxidizing bacteria (AOB) in the cathode layer, whereas a high one enhanced the richness of nitrite-oxidizing bacteria (NOB) in each medium; the dominant genera in AOA, AOB, and NOB were Candidatus Nitrosotenuis, Nitrosomonas, and Nitrobacter. Moreover, a high C/N ratio facilitated the growth of Nitrosomonas, while it inhibited the growth of Candidatus Nitrosotenuis. …”
Publicado 2020
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820por Kellen de Souza Cardoso, Camila, Gondim Peixoto, Maria do Rosário, dos Santos Rodrigues, Ana Paula, Rodrigues Mendonça, Carolina, de Oliveira, Cesar, Aparecida Silveira, Erika“…Smoking for total body BMD (p = 0.045); BMI ≥ 50kg/m(2) for vertebral column and hip; menopause for hip; high C-reactive protein (CRP) levels (p = 0.049), insufficient zinc (p = 0.010) and previous fracture for vertebral column (p = 0.007). …”
Publicado 2020
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