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  1. 1001
    “…As a result, the BNTH(x)/LSMO ferromagnetic-ferroelectric composite films integrated on Si substrate exhibit high c-axis orientation. The Nd(3+)/Hf(4+) co-substituted BNTH(x) films have the lower leakage current and the better ferroelectric properties than the mono-substituted Bi(4)Ti(3)O(12) (Bi(3.15)Nd(0.85)Ti(3)O(12) and Bi(4)Ti(2.95)Hf(0.05)O(12)) films. …”
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    Integration of c-axis oriented Bi(3.15)Nd(0.85)Ti(2.95)Hf(0.05)O(12)/La(0.67)Sr(0.33)MnO(3) ferromagnetic-ferroelectric composite film on Si substrate
  2. 1002
    “…The univariate Cox analysis showed an association between mortality and age, diabetes, previous CVEs, Charlson comorbidity index, low albumin and pre-albumin, high C-reactive protein (CRP), low lean tissue and high OH/ECW. …”
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    Any grade of relative overhydration is associated with long-term mortality in patients with Stages 4 and 5 non-dialysis chronic kidney disease
  3. 1003
    “…By regulating the C3b density on the bead surface, we observe that high C3b densities are important for conversion of C5, but not C3, by AP convertases. …”
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    Functional Characterization of Alternative and Classical Pathway C3/C5 Convertase Activity and Inhibition Using Purified Models
  4. 1004
    “…Multivariate logistic regression analyses with progression ≥ 2 mSASSS units over 5 years or development of new syndesmophytes as the dependent variable showed that presence of baseline AS-related spinal radiographic alterations and obesity (OR 3.78, 95% CI 1.3 to 11.2) were independent predictors of spinal radiographic progression in both sexes. High C-reactive protein (CRP) was a significant predictor in men, with only a trend seen in women. …”
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    A five-year prospective study of spinal radiographic progression and its predictors in men and women with ankylosing spondylitis
  5. 1005
    “…The depressive symptoms have been associated with increased disabilities, and the depressive symptoms-related elevation of high C-reactive protein (CRP) has been proposed as a possible mechanism. …”
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    No association between C-reactive protein and depressive symptoms among the middle-aged and elderly in China: Evidence from the China Health and Retirement Longitudinal Study
  6. 1006
    “…Multivariate analysis identified VICM as a predictor of longer OS (p = 0.026). Similarly, a high C3M/PRO-C3 ratio predicted for increased OS (p = 0.034). …”
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    Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients
  7. 1007
    “…Sixty-four multiexon and 29 single-exon CNVs with high C-scores were assessed by Multiplex Ligation-dependent Probe Amplification (MLPA). …”
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    Atlas-CNV: a validated approach to call single-exon CNVs in the eMERGESeq gene panel
  8. 1008
    “…METHODS: Domatinostat was evaluated in PD-1 blockade-insensitive CTL-low (CT26) and CTL-high (C38) syngeneic models alone and in combination with different immune-inhibitory and -stimulatory approaches. …”
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    Domatinostat favors the immunotherapy response by modulating the tumor immune microenvironment (TIME)
  9. 1009
    “…The cZFP609 was delivered into ECs, and detained HIF1α in the cytoplasm via its interaction with HIF1α, thereby inhibiting VEGFA expression and endothelial angiogenic functions. Meantime, the high cZFP609 expression was observed in the plasma of the patients with atherosclerotic or diabetic lower extremity peripheral artery disease, associated with reduced ankle-brachial index. …”
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    Smooth muscle SIRT1 reprograms endothelial cells to suppress angiogenesis after ischemia
  10. 1010
    “…While, smoking was more prevalent among the SVD group as compare to MVD group (36.3% vs 28.4%, P = 0.05). The high-C Lesion was observed in a significantly higher number of younger patients with MVD as compared to SVD group (48.8% vs 39.2%, P = 0.021). …”
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    Comparative assessment of clinical profile and outcomes after primary percutaneous coronary intervention in young patients with single vs multivessel disease
  11. 1011
    “…Even though the recommended high C(min) of teicoplanin was associated with better clinical outcome, reaching the target concentration is challenging. …”
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    Clinical efficacy and safety in patients treated with teicoplanin with a target trough concentration of 20 μg/mL using a regimen of 12 mg/kg for five doses within the initial 3 days
  12. 1012
    “…In contrast to cDC, high pDC in TNBC was significantly associated with better disease-specific and disease-free survival consistently in both cohorts. High cDC TNBC tumors enriched not only inflammation and immune-related, but also metastasis-related gene sets in Gene Set Enrichment Analysis, whereas high pDC TNBC enriched inflammation and immune -related gene sets including IFN-γ signaling more strongly than cDC. pDC TNBC correlated with CD8(+), CD4(+) memory, IFN-γ score, and cytolytic activity stronger than cDC TNBC. …”
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    Plasmacytoid Dendritic Cell (pDC) Infiltration Correlate with Tumor Infiltrating Lymphocytes, Cancer Immunity, and Better Survival in Triple Negative Breast Cancer (TNBC) More Strongly than Conventional Dendritic Cell (cDC)
  13. 1013
    “…The patients were then divided into groups A (MPV(high) and CA19-9(low)), B (MPV(high) and CA19-9(high)), C (MPV(low) and CA19-9(low)), and D (MPV(low) and CA19-9(high)), with 5-year OS rates of 73.2%, 40.4%, 25.8%, and 10.3%, respectively (P = 0.0002), and 5-year DSS rates of 80.8%, 44.9%, 27.3%, and 16.4%, respectively (P = 0.0003). …”
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    Decreased mean platelet volume predicts poor prognosis in patients with pancreatic cancer
  14. 1014
    “…SP2 was characterized by high C-reactive protein, early need for mechanical ventilation, and the highest rate of ARDS. …”
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    Identification of Distinct Clinical Subphenotypes in Critically Ill Patients With COVID-19
  15. 1015
    “…In the case of SLEDAI score ≤ 4, the preterm birth rate was higher in the pre-pregnancy low C3 group (< 85 mg/dl) (42.1%) than in the high C3 group (C3 ≥ 85 mg/dl) (14.7%) (P = 0.018). …”
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    Pre-pregnancy serum complement C3 level is a predictor of preterm birth for pregnancies with systemic lupus erythematosus
  16. 1016
    “…Model-based clustering shows that SCLC has subdivided into 2 major proteomic subsets defined by either TTF-1(high)/c-MYC(low) or TTF-1(low)/c-MYC(high), which may correspond to 2 mutually exclusive molecular subgroups: NSCLC-like or SCLC-like, respectively. …”
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    TTF-1 and c-MYC-defined Phenotypes of Large Cell Neuroendocrine Carcinoma and Delta-like Protein 3 Expression for Treatment Selection
  17. 1017
    “…The tropical climate of the Caribbean Sea and associated sediment run-off, together with the relatively high primary production of T. testudinum, influencing biotic and abiotic drivers of C(org) storage linked to seagrass and soil respiration rates, explains their relatively high C(org) stocks and accumulation rates when compared to other meadows globally. …”
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    Seagrass blue carbon stocks and sequestration rates in the Colombian Caribbean
  18. 1018
    “…This was significantly influenced by the presence of comorbidities, hypotension, hypoxia, heart failure, acute respiratory distress, hypernatremia, abnormal liver profile, high C-reactive protein, and positive blood culture. …”
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    Acute kidney injury in children with COVID-19: a retrospective study
  19. 1019
    “…Also, we established a prognostic nomogram with a high C-index and accomplished good prediction accuracy. …”
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    Identification of an m6A-Related lncRNA Signature for Predicting the Prognosis in Patients With Kidney Renal Clear Cell Carcinoma
  20. 1020
    por Azarkar, Ghodsiyeh, Osmani, Freshteh
    Publicado 2021
    “…CONCLUSIONS: Patients with, lower lymphocyte counts in hemogram, platelet count and serum albumin, and high C-reactive protein level, and also patients with comorbidities may have more risk for death. …”
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    Clinical characteristics and risk factors for mortality in COVID-19 inpatients in Birjand, Iran: a single-center retrospective study
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