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  1. 1061
    “…In ECLIPSE, cachexia was defined as weight-loss > 5% in the past 12 months or low BMI and 3/5 criteria: decreased muscle strength, anorexia, abnormal biochemistry (anemia or high c-reactive protein (> 5 mg/l)), fatigue, and low FFMI. …”
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    Heme metabolism genes Downregulated in COPD Cachexia
  2. 1062
    “…Of the multivariable models, the model including clinico-pathologic factors and both qualitative and quantitative imaging parameters showed good discrimination with a high C index value of 0.825 (95% CI: 0.755–0.896). …”
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    Prognostic Factors of Disease Recurrence in Breast Cancer Using Quantitative and Qualitative Magnetic Resonance Imaging (MRI) Parameters
  3. 1063
    “…RESULTS: The risk factors in ACS group were overweight (64.10%), hypertension (49.88%), hyperlipidemia (40.72%), diabetes (23.37%), depression or anxiety (16.63%), gynecological diseases (16.39%), Hyperuricemia (14.94%), family history of early-onset CHD (14.94%), hyperhomocysteinemia (11.33%), hypothyroidism (9.64%), hypercholesterolemia (8.43%) and high C-reactive protein (7.47%), and were significant difference (P < 0.01) compared with that of the control group. …”
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    The characteristics of risk factors in Chinese young women with acute coronary syndrome
  4. 1064
    “…Multivariate analysis of NIR spectra signals of field aggregates separated root aggregates with high concentrations of [Image: see text] and [Image: see text] (41.5% of explained variance, axis I) from those biogenic aggregates, including root aggregates, with large concentrations of C and high C:N ratio (21.6% of total variability, axis II). …”
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    Unveiling the age and origin of biogenic aggregates produced by earthworm species with their NIRS fingerprint in a subalpine meadow of Central Pyrenees
  5. 1065
    “…The model showed good discrimination with a C-index of 0.82 (95% confidence interval 0.73376–0.90 624) in training cohortn and 0.89 (95% CI 0.868, 0.902) in validation cohort, an AUC of 0.795 in training cohort, 0.94 in validation cohort and good calibration. A high C-index value of 0.66 was reached in the interval validation assessment. …”
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    Predicting bleeding risk in a Chinese immune thrombocytopenia (ITP) population: development and assessment of a new predictive nomogram
  6. 1066
    “…Mortality was associated with those that were admitted to ICU (19% vs 0; p = 0.009), mechanically ventilated (31% vs 0; p = 0.001), had DM (20% vs 2.3%; p = 0.032), older (62 vs 47 years; p = 0.045), had high total bilirubin (43% vs 2.3%; p = 0.007) and those with high C-reactive protein (186 vs 90 mg/dL; p = 0.009) and low corrected calcium (15% vs 0%; p = 0.047). …”
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    Clinical characteristics and outcomes of the first 63 adult patients hospitalized with COVID-19: An experience from Oman
  7. 1067
    “…Hnf1b:CreER(T2);Kras(G12V) (cKras(Hnf1b/+)) mice received 1 (Low), 5 (Mod) or 10 (High) mg per 20 g body weight to recombine cKras in low (cKras(Low)), moderate (cKras(Mod)), and high (cKras(High)) percentages of pancreatic ducts. …”
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    Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer
  8. 1068
    “…Secondary analysis (patients, N = 829), further adjusted for high C-reactive protein (>21 mg/dL) and LDH (>430 mU/mL) levels yielded consistent findings. …”
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    Nutritional parameters associated with prognosis in non-critically ill hospitalized COVID-19 patients: The NUTRI-COVID19 study
  9. 1069
    “…The findings showed that patients with C. psittaci pneumonia presented with normal or slightly increased leucocytes and procalcitonin, and high C-reactive protein levels. Computed tomography manifestations included consolidation of lung parenchyma, with air bronchogram and pleural effusion in some patients. mNGS analysis results were obtained within 48–72 h. …”
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    Application of metagenomic next-generation sequencing in the diagnosis of severe pneumonia caused by Chlamydia psittaci
  10. 1070
    “…H3K79me3 expression was increased in those with high C-reactive protein levels. Decreased KDM6B protein expressions were noted in those with a high hypoxic load, and associated with a higher risk for incident cardiovascular events or hypertension. …”
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    H3K23/H3K36 hypoacetylation and HDAC1 up-regulation are associated with adverse consequences in obstructive sleep apnea patients
  11. 1071
    “…CONCLUSIONS: A single bolus of 2 mg/kg levobupivacaine in the ESP block resulted in a short T(max) with high C(max). Adding epinephrine to levobupivacaine decreased the C(max) and delayed the T(max) after ESP blocks but had no effect on postoperative analgesia. …”
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    Comparison of plasma levobupivacaine concentrations with and without epinephrine following erector spinae plane block for breast cancer surgery: a randomized controlled trial
  12. 1072
    “…Additionally, males with high C5 had a higher synovial fluid concentration of sC5b-C9 compared to males with low C5. …”
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    Sex-Differences and Associations Between Complement Activation and Synovial Vascularization in Patients with Late-Stage Knee Osteoarthritis
  13. 1073
    “…Using a mixed-model analysis, interleukin-10 at admission to the NICU (p = 1.5 × 10(−13)) and tau protein at the end of TH/rewarming (p = 0.036) and after rewarming (p = 0.0015) were significantly associated with higher cDTI scores, suggesting that high cDTI scores were related to the intensity of the early inflammatory response and the severity of neuronal impairment after TH. …”
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    Development of a composite diffusion tensor imaging score correlating with short-term neurological status in neonatal hypoxic–ischemic encephalopathy
  14. 1074
    “…Pairwise comparisons used the Steel–Dwass test. RESULTS: The high-cIOP subgroup had significantly worse mean deviation (MD), temporal, superior, and inferior loss of circumpapillary retinal nerve fiber layer thickness (cpRNFLT), and large cupping. …”
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    Clinical characteristics of glaucoma patients with various risk factors
  15. 1075
    “…The dynamic nomogram achieved a high C-index of 0.909 in the training set and 0.905 in the validation set. …”
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    Establishment of dynamic nomogram and risk score models for T2DM: a retrospective cohort study in Beijing
  16. 1076
    “…METHODS AND RESULTS: Among 33 patients with unexplained hypertransaminasemia from 11 hospitals and 13 of their relatives, seven individuals with abnormally high C27‐BA levels (>50% of total BAs) were identified by high‐performance liquid chromatography‐mass spectrometry. …”
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    Beneficial effect of ursodeoxycholic acid in patients with acyl‐CoA oxidase 2 (ACOX2) deficiency–associated hypertransaminasemia
  17. 1077
    “…In univariable analysis, age above the median, time to diagnosis, high C-reactive protein, and high N-terminal pro-B-type natriuretic peptide (NT-proBNP) were associated with cardiogenic shock [odds ratio (OR) 6.13 (1.02–36.9), 2.79 (1.15–6.74), 2.08 (1.05–4.12), and 1.70 (1.04–2.78), respectively]. …”
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    Impact of time to diagnosis on the occurrence of cardiogenic shock in MIS-C post-COVID-19 infection
  18. 1078
    “…Interestingly, despite GF mice carrying very high C. rodentium burdens, passage across the mucus layer and infection of their colonic epithelium was impaired as compared to SPF mice. …”
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    A40 GUT MICROBIOTA PROMOTES NUTRIENT AVAILABLITY AND PATHOGENESIS OF AN ATTACHING/ EFFACING BACTERIAL PATHOGEN
  19. 1079
    “…This led to 20–40% of clinical samples having high C(T) values and therefore assays vying for an EUA were failing to achieve the 80% Percent Positive Agreement (PPA) threshold required. …”
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    Standardization and Comparison of Emergency Use Authorized COVID-19 Assays and Testing Laboratories.
  20. 1080
    “…Patients transferred from a single long-term care acute hospital (LTACH) with high C. auris prevalence were placed in empiric isolation on admission and screened for C. auris colonization via axilla and groin surveillance swabs. …”
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    2483. Rise in inpatient Candida auris cases at a tertiary hospital in Washington, DC during the COVID-19 pandemic
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