Mediterranean diet based intervention in pregnancy to improve maternal and fetal outcomes: Methodological challenges and lessons learned from the multicentre ESTEEM study

por Al Wattar, Bassel H., Dodds, Julie, Placzek, Anna, Spyreli, Eleni, Higgins, Sally, Moore, Amanda, Hooper, Richard, Beresford, Lee, Roseboom, Tessa J., Bes-Rastrollo, Maira, Hitman, Graham, Khan, Khalid S., Thangaratinam, Shakila
Publicado 2017

Altered Nutrient Uptake Causes Mitochondrial Dysfunction in Senescent CD8(+) EMRA T Cells During Type 2 Diabetes

por Callender, Lauren A., Carroll, Elizabeth C., Garrod-Ketchley, Conor, Schroth, Johannes, Bystrom, Jonas, Berryman, Victoria, Pattrick, Melanie, Campbell-Richards, Desiree, Hood, Gillian A., Hitman, Graham A., Finer, Sarah, Henson, Sian M.
Publicado 2021

Total Soluble and Endogenous Secretory Receptor for Advanced Glycation End Products as Predictive Biomarkers of Coronary Heart Disease Risk in Patients With Type 2 Diabetes: An Ana...

por Colhoun, Helen M., Betteridge, D. John, Durrington, Paul, Hitman, Graham, Neil, Andrew, Livingstone, Shona, Charlton-Menys, Valentine, Bao, Weihang, DeMicco, David A., Preston, Gregory M., Deshmukh, Harshal, Tan, Kathryn, Fuller, John H.
Publicado 2011

Maternal BMI and nutritional status in early pregnancy and its impact on neonatal outcomes at birth in Bangladesh

por Bhowmik, Bishwajit, Siddique, Tasnima, Majumder, Anindita, Mdala, Ibrahimu, Hossain, Israt A., Hassan, Zahid, Jahan, Ishrat, Moreira, Nayla Cristina do V., Alim, Abdul, Basit, Abdul, Hitman, Graham A., Khan, Abul Kalam A., Hussain, Akhtar
Publicado 2019

The effects of vitamin D(2) or D(3) supplementation on glycaemic control and related metabolic parameters in people at risk of type 2 diabetes: protocol of a randomised double-blin...

por Menon, Ravi K, Rickard, Anna P, Mannan, Nasima, Timms, Peter M, Sharp, Stephen J, Martineau, Adrian, Boucher, Barbara J, Chowdhury, Tahseen A, Griffiths, Christopher J, Griffin, Simon J, Hitman, Graham A, Forouhi, Nita G
Publicado 2013

Effects of vitamin D(2) or D(3) supplementation on glycaemic control and cardiometabolic risk among people at risk of type 2 diabetes: results of a randomized double‐blind placebo‐...

por Forouhi, N. G., Menon, R. K., Sharp, S. J., Mannan, N., Timms, P. M., Martineau, A. R., Rickard, A. P., Boucher, B. J., Chowdhury, T. A., Griffiths, C. J., Greenwald, S. E., Griffin, S. J., Hitman, G. A.
Publicado 2016

Effectiveness and acceptability of myo-inositol nutritional supplement in the prevention of gestational diabetes (EMmY): a protocol for a randomised, placebo-controlled, double-bli...

por Amaefule, Chiamaka Esther, Drymoussi, Zoe, Dodds, Julie, Sweeney, Lorna, Pizzo, Elena, Daru, Jahnavi, Robson, John, Poston, Lucilla, Khalil, Asma, Myers, Jenny, Harden, Angela, Hitman, Graham A, Khan, Khalid, Zamora, Javier, Huda, Mohammed S B, Thangaratinam, Shakila
Publicado 2018

Vitamin B(12) insufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes

por Adaikalakoteswari, Antonysunil, Finer, Sarah, Voyias, Philip D, McCarthy, Ciara M, Vatish, Manu, Moore, Jonathan, Smart-Halajko, Melissa, Bawazeer, Nahla, Al-Daghri, Nasser M, McTernan, Philip G, Kumar, Sudhesh, Hitman, Graham A, Saravanan, Ponnusamy, Tripathi, Gyanendra
Publicado 2015

Glucolipotoxicity initiates pancreatic β-cell death through TNFR5/CD40-mediated STAT1 and NF-κB activation

por Bagnati, Marta, Ogunkolade, Babatunji W, Marshall, Catriona, Tucci, Carmen, Hanna, Katie, Jones, Tania A, Bugliani, Marco, Nedjai, Belinda, Caton, Paul W, Kieswich, Julius, Yaqoob, Muhammed M, Ball, Graham R, Marchetti, Piero, Hitman, Graham A, Turner, Mark D
Publicado 2016

Mediterranean-style diet in pregnant women with metabolic risk factors (ESTEEM): A pragmatic multicentre randomised trial

por H. Al Wattar, Bassel, Dodds, Julie, Placzek, Anna, Beresford, Lee, Spyreli, Eleni, Moore, Amanda, Gonzalez Carreras, Francisco J., Austin, Frances, Murugesu, Nilaani, Roseboom, Tessa J., Bes-Rastrollo, Maira, Hitman, Graham A., Hooper, Richard, Khan, Khalid S., Thangaratinam, Shakila
Publicado 2019

Diet and physical activity in pregnancy to prevent gestational diabetes: a protocol for an individual participant data (IPD) meta-analysis on the differential effects of interventi...

por Coomar, Dyuti, Hazlehurst, Jonathan M, Austin, Frances, Foster, Charlie, Hitman, Graham A, Heslehurst, Nicola, Iliodromiti, Stamatina, Betran, Ana Pilar, Moss, Ngawai, Poston, Lucilla, Nirantharakumar, Krishnarajah, Roberts, Tracy, Simpson, Sharon A, Teede, Helena J, Riley, Richard, Allotey, John, Thangaratinam, Shakila
Publicado 2021

Metformin in the prevention of type 2 diabetes after gestational diabetes in postnatal women (OMAhA): a UK multicentre randomised, placebo-controlled, double-blind feasibility tria...

por Bolou, Angeliki, Drymoussi, Zoe, Lanz, Doris, Amaefule, Chiamaka Esther, Gonzalez Carreras, Francisco Jose, Pardo Llorente, Maria del Carmen, Dodds, Julie, Pizzo, Elena, Thomas, Amy, Heighway, James, Harden, Angela, Sanghi, Anita, Hitman, Graham, Zamora, Javier, Pérez, Teresa, Huda, Mohammed S B, Thangaratinam, Shakila
Publicado 2023

Acceptability and adherence to a Mediterranean diet in the postnatal period to prevent type 2 diabetes in women with gestational diabetes in the UK: a protocol for a single-arm fea...

por Bolou, Angeliki, Lanz, Doris, Drymoussi, Zoe, Gonzalez Carreras, Francisco Jose, Austin, Frances, Dodds, Julie, Mehay, Anita, Pizzo, Elena, Thomas, Amy, Heighway, James, Sanghi, Anita, Harden, Angela, Pérez, Teresa, Pardo Llorente, Maria del Carmen, Hitman, Graham, Huda, Mohammed SB, Thangaratinam, Shakila
Publicado 2021

Effect of atorvastatin on C-reactive protein and benefits for cardiovascular disease in patients with type 2 diabetes: analyses from the Collaborative Atorvastatin Diabetes Trial

por Soedamah-Muthu, Sabita S., Livingstone, Shona J., Charlton-Menys, Valentine, Betteridge, D. John, Hitman, Graham A., Neil, H. Andrew W., Bao, Weihang, DeMicco, David A., Preston, Gregory M., Fuller, John H., Stehouwer, Coen D. A., Schalkwijk, Casper G., Durrington, Paul N., Colhoun, Helen M.
Publicado 2015

Adiposity-Related Heterogeneity in Patterns of Type 2 Diabetes Susceptibility Observed in Genome-Wide Association Data

por Timpson, Nicholas J., Lindgren, Cecilia M., Weedon, Michael N., Randall, Joshua, Ouwehand, Willem H., Strachan, David P., Rayner, N. William, Walker, Mark, Hitman, Graham A., Doney, Alex S.F., Palmer, Colin N.A., Morris, Andrew D., Hattersley, Andrew T., Zeggini, Eleftheria, Frayling, Timothy M., McCarthy, Mark I.
Publicado 2009

The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction

por Trompet, Stella, Postmus, Iris, Warren, Helen R., Noordam, Raymond, Smit, Roelof A. J., Theusch, Elizabeth, Li, Xiaohui, Arsenault, Benoit, Chasman, Daniel I., Hitman, Graham A., Munroe, Patricia B., Rotter, Jerome I., Psaty, Bruce M., Caulfield, Mark J., Krauss, Ron M., Cupples, Adrienne L., Jukema, Wouter J.
Publicado 2022

Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus

por Bell, Christopher G., Finer, Sarah, Lindgren, Cecilia M., Wilson, Gareth A., Rakyan, Vardhman K., Teschendorff, Andrew E., Akan, Pelin, Stupka, Elia, Down, Thomas A., Prokopenko, Inga, Morison, Ian M., Mill, Jonathan, Pidsley, Ruth, Deloukas, Panos, Frayling, Timothy M., Hattersley, Andrew T., McCarthy, Mark I., Beck, Stephan, Hitman, Graham A.
Publicado 2010

Population-Specific Risk of Type 2 Diabetes Conferred by HNF4A P2 Promoter Variants: A Lesson for Replication Studies

por Barroso, Inês, Luan, Jian’an, Wheeler, Eleanor, Whittaker, Pamela, Wasson, Jon, Zeggini, Eleftheria, Weedon, Michael N., Hunt, Sarah, Venkatesh, Ranganath, Frayling, Timothy M., Delgado, Marcos, Neuman, Rosalind J., Zhao, Jinghua, Sherva, Richard, Glaser, Benjamin, Walker, Mark, Hitman, Graham, McCarthy, Mark I., Hattersley, Andrew T., Permutt, M. Alan, Wareham, Nicholas J., Deloukas, Panagiotis
Publicado 2008

Myo-inositol nutritional supplement for prevention of gestational diabetes (EMmY): a randomised, placebo-controlled, double-blind pilot trial with nested qualitative study

por Amaefule, Chiamaka Esther, Drymoussi, Zoe, Gonzalez Carreras, Francisco Jose, Pardo Llorente, Maria del Carmen, Lanz, Doris, Dodds, Julie, Sweeney, Lorna, Pizzo, Elena, Thomas, Amy, Heighway, James, Daru, Jahnavi, Sobhy, Soha, Poston, Lucilla, Khalil, Asma, Myers, Jenny, Harden, Angela, Hitman, Graham, Khan, Khalid Saeed, Zamora, Javier, Pérez, Teresa, Huda, Mohammed S B, Thangaratinam, Shakila
Publicado 2022

Effectiveness and acceptability of metformin in preventing the onset of type 2 diabetes after gestational diabetes in postnatal women: a protocol for a randomised, placebo-controll...

por Amaefule, Chiamaka Esther, Bolou, Angeliki, Drymoussi, Zoe, Gonzalez Carreras, Francisco Jose, Pardo Llorente, Maria del Carmen, Lanz, Doris, Dodds, Julie, Sweeney, Lorna, Pizzo, Elena, D’Amico, Maria, Thomas, Amy, Heighway, James, Daru, Jahnavi, Sobhy, Soha, Robson, John, Sanghi, Anita, Zamora, Javier, Harden, Angela, Hitman, Graham, Khan, Khalid, Pérez, Teresa, Huda, Mohammed SB, Thangaratinam, Shakila
Publicado 2020