“…Subjects were 79 males (mean age ± standard deviation; 62.1 ± 10.0 years) and 79 females (60.3 ± 10.3 y) who attended a health examination screening in the town of Hokkaido, Japan. Serum 8-OHdG, Mn-SOD, and oLAB levels were measured by ELISA and serum carotenoids levels were measured by HPLC. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, the first significant increase in ADRHI per 100,000 people at WBGT(max) differed across each region, at a WBGT(max) of 24°C in Hokkaido-Tohoku, 25°C in Kanto, Kansai, and Chugoku, 26°C in Chubu, 27°C in Shikoku, and 28°C in Kyushu-Okinawa. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Four lectures were delivered to 108 nurses from Hokkaido to Okinawa and remote islands. Overall, 90% of the participants were female nurses. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: We studied patients examined using CS and US upon suspicion of IMC in Hokkaido University Hospital between April 2018 and February 2021. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The C-BARQ was administered to dogs that previously passed the aptitude test for therapy training at the Hokkaido Volunteer Dog Association, assessing their behavioural displays. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Invasive B. terrestris showed low prevalence of non/low-sporulating V. bombi infections and shared the same V. bombi haplotype with B. hypocrita found in Hokkaido, where B. terrestris is present, and in Honshu, where B. terrestris is absent. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The purpose of the present study was to conduct a field study and create wild-derived quail strains using the breeding stocks in Tokachi, Hokkaido, Japan. Field observations from 2019 to 2022 indicate that wild quails migrate and stay at reproductive sites from late April to late October. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Mapping using Model 3 showed that the high-risk areas were predominantly located in northern Japan, excluding Hokkaido. CONCLUSION: Access to mechanical thrombectomy was estimated, and regional differences were observed. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we conducted a clinical study of c4G12, a canine chimeric anti-PD-L1 antibody, to assess its safety and efficacy in dogs with various advanced malignant tumours (n = 12) at the Veterinary Teaching Hospital of Hokkaido University from 2018 to 2023. Dogs with digit or foot pad malignant melanoma (n = 4), osteosarcoma (n = 2), hemangiosarcoma (n = 1), transitional cell carcinoma (n = 1), nasal adenocarcinoma (n = 1), B-cell lymphoma (n = 1), or undifferentiated sarcoma (n = 2) were treated with 2 or 5 mg/kg c4G12 every 2 weeks. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here we show that apicomplexans isolated from twelve taxonomically diverse rhabdocoel taxa and one species of proseriate collected in four geographically distinct areas around the Pacific Ocean (Okinawa, Hokkaido, and British Columbia) and the Caribbean Sea (Curaçao) all belong to the apicomplexan genus Rhytidocystis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: Health insurance data and LTCI data were combined into a database of 1,020 individuals in two farming communities in Hokkaido who were enrolled in Citizen's Health Insurance. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…On the other hand, an avirulent H5N1 strain, A/duck/Hokkaido/Vac-1/2004 (Vac1) (H5N1), acquired intranasal pathogenicity after a pair of di-basic amino acid residues was introduced into the cleavage site of the HA, followed by two passages by air sac inoculation in chicks. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…K town, located in the Hokkaido prefecture of Japan, was selected as the location for this study. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Of the 590 dogs examined, 6 dogs (1.02%, 6/590) were carriers: 3 dogs (2.27%, 3/132) from the Kinki district and the other 3 dogs from the Hokkaido, Kanto, and Shikoku districts. The retrospective survey revealed 23 affected dogs, among which, 19 dogs (82.6%) were born within the last 7 years. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: We assessed 1784 native Japanese mother-child pairs drawn from the ongoing birth cohort of The Hokkaido Study on Environment and Children’s Health. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Among 4981 children who became 8 years old by November 2014 and were contactable for this survey by The Hokkaido Study of Environment and Children's Health, 1631 (32.7%), who had data for 2D/4D and Pre-school Activities Inventory (PSAI) as well as data for the survey at baseline, were available for analysis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This cross-sectional study included 3 groups of patients attending Hokkaido University Hospital: PAH, chronic thromboembolic pulmonary hypertension (CTEPH), and connective tissue diseases (CTD) without PAH (CTD-non-PAH) group. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…MATERIALS AND METHODS: Data from 103 patients with COPD included in the Hokkaido COPD cohort study were analyzed. Computed tomography (CT) attenuation values of thoracic vertebrae 4, 7, and 10 were measured using custom software, and the average value (average bone density; ABD(4,7,10)) was calculated. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Data collection was performed for 56 patients with 59 treatment sites who received proton beam therapy at Hokkaido University Hospital between March 2014 and July 2015. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In total, 14 642 women aged 20 to 69 years undergoing routine screening at 3 centers in Hokkaido were enrolled. Conventional cytology and HPV testing were carried out. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso