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561por Otagiri, Shinsuke, Ohnishi, Shunsuke, Miura, Arisa, Hayashi, Hiroshi, Kumagai, Izumi, Ito, Yoichi M, Katsurada, Takehiko, Nakamura, Shiro, Okamoto, Rika, Yamahara, Kenichi, Cho, Kyu Yong, Isoe, Toshiyuki, Sato, Norihiro, Sakamoto, Naoya“…ETHICS AND DISSEMINATION: The Institutional Review Board of Hokkaido University Hospital approved this study protocol (approval number H29-6). …”
Publicado 2018
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562por Takeuchi, Satoshi, Shiga, Tohru, Hirata, Kenji, Taguchi, Jun, Magota, Keiichi, Ariga, Shin, Gouda, Tomohiro, Ohhara, Yoshihito, Homma, Rio, Shimizu, Yasushi, Kinoshita, Ichiro, Tsuji, Yasushi, Homma, Akihiro, Iijima, Hiroaki, Tamaki, Nagara, Dosaka-Akita, Hirotoshi“…ETHICS AND DISSEMINATION: This study is conducted in accordance with the Declaration of Helsinki and has received ethical approval from the institutional review board of the Hokkaido University Hospital (approval number: 015-402). …”
Publicado 2018
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563por Aung, Meiji Soe, Urushibara, Noriko, Kawaguchiya, Mitsuyo, Sumi, Ayako, Takahashi, Seika, Ike, Miyo, Ito, Masahiko, Habadera, Satoshi, Kobayashi, Nobumichi“…In this study, prevalence of S. argenteus among human clinical isolates, and their clonal diversity and genetic characteristics of virulence factors were investigated in Hokkaido, the northern main island of Japan. During a four-month period starting from March 2019, twenty-four S. argenteus and 4330 S. aureus isolates were recovered from clinical specimens (the ratio of S. argenteus to S. aureus :0.0055). …”
Publicado 2019
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564por Takei, Nozomu, Suzuki, Masaru, Makita, Hironi, Konno, Satoshi, Shimizu, Kaoruko, Kimura, Hiroki, Kimura, Hirokazu, Nishimura, Masaharu“…PATIENTS AND METHODS: We analyzed 278 COPD patients who participated in the Hokkaido COPD cohort study and who did not meet the criteria for alpha-1 antitrypsin deficiency. …”
Publicado 2019
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565“…RESULTS: Here we performed RNA-seq analysis using cold-stressed post-meiotic anther samples from a cold-tolerant, Erythroceros Hokkaido (ERY), and a cold-susceptible commercial cultivar Sant’Andrea (S.AND). …”
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566por Sho, Takuya, Suda, Goki, Ogawa, Koji, Kimura, Megumi, Shimazaki, Tomoe, Maehara, Osamu, Shigesawa, Taku, Suzuki, Kazuharu, Nakamura, Akihisa, Ohara, Masatsugu, Umemura, Machiko, Kawagishi, Naoki, Natsuizaka, Mitsuteru, Nakai, Masato, Morikawa, Kenichi, Furuya, Ken, Baba, Masaru, Yamamoto, Yoshiya, Kobayashi, Tomoe, Meguro, Takashi, Saga, Akiyoshi, Miyagishima, Takuto, Yokoo, Hideki, Kamiyama, Toshiya, Taketomi, Akinobu, Sakamoto, Naoya“…METHODS: Among patients who were administered lenvatinib for advanced HCC between April and October 2018 in Hokkaido University Hospital and related hospitals, we evaluated those who were followed for more than 2 months and whose treatment response was evaluated via dynamic computed tomography at baseline and 2 months after treatment initiation. …”
Publicado 2019
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567por Motegi, Hiroaki, Yamaguchi, Shigeru, Ishi, Yukitomo, Endo, Shogo, Kobayashi, Hiroyuki, Terasaka, Shunsuke, Suzuki, Masanobu, Nakamaru, Yuji, Homma, Akihiro, Houkin, Kiyohiro“…METHODS: Thirty-four patients treated at Hokkaido University were included. Stages of craniocaudal progression were defined as Nasally/Paranasally localized (NP), Frontal Base progression (FB), and Brain invasion (BI). …”
Publicado 2019
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568por Shirane, Yuri, Mori, Fumihiko, Yamanaka, Masami, Nakanishi, Masanao, Ishinazaka, Tsuyoshi, Mano, Tsutomu, Jimbo, Mina, Sashika, Mariko, Tsubota, Toshio, Shimozuru, Michito“…We developed a noninvasive method that uses photographs to assess the body condition of free-ranging brown bears (Ursus arctos) in the Shiretoko Peninsula, Hokkaido, Japan. First, we weighed and measured 476 bears captured during 1998–2017 and calculated their body condition index (BCI) based on residuals from the regression of body mass against body length. …”
Publicado 2020
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569“…METHODS AND ANALYSIS: The study will be conducted at the Motowanishi Family Clinic in Hokkaido, Japan, using patients who have attended the clinic for over 10 years. …”
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570por Okamoto, Michinari, Yamaguchi, Shigeru, Ishi, Yukitomo, Motegi, Hiroaki, Kobayashi, Hiroyuki, Terasaka, Shunsuke, Houkin, Kiyohiro“…Methods: We retrospectively analyzed all patients with PCNSL treated at Hokkaido University Hospital between 2001 and 2018 to assess the effect of selection for resection on the response of Methotrexate chemotherapy. …”
Publicado 2020
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571“…Specifically, we collected the historical information of clinic visits caused by HFMD infection between years 2009 and 2018 respectively from public records of Tokyo, Hokkaido, and Osaka, Japan. When applied to the city networks we modelled, our method successfully identified pre-outbreak signals in an average 5 weeks ahead of the HFMD outbreak. …”
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572por Aung, Meiji Soe, Urushibara, Noriko, Kawaguchiya, Mitsuyo, Hirose, Mina, Ike, Miyo, Ito, Masahiko, Kobayashi, Nobumichi“…In this study, the prevalence and genetic characteristics of virulence factors and drug resistance determinants were investigated for 82 S. argenteus clinical isolates in Hokkaido, Japan, for a one-year period starting in August 2019. …”
Publicado 2021
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573por Oba-Yamamoto, Chiho, Kameda, Hiraku, Miyoshi, Hideaki, Sekizaki, Tomonori, Takase, Takahiro, Yanagimachi, Tsuyoshi, Fujita, Yukihiro, Nomoto, Hiroshi, Cho, Kyu Yong, Nakamura, Akinobu, Nagai, So, Atsumi, Tatsuya“…METHODS: This prospective cross-sectional study was carried out on acromegalic patients admitted to Hokkaido University hospital between June 2011 and May 2018. …”
Publicado 2021
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574por Suzuki, Masanobu, Vyskocil, Erich, Ogi, Kazuhiro, Matoba, Kotaro, Nakamaru, Yuji, Homma, Akihiro, Wormald, Peter J., Psaltis, Alkis J.“…Methods: Three otolaryngologists in Hokkaido, Japan, were trained to perform frontal sinus dissections on novel 3D sinus models of increasing difficulty, by two rhinologists located in Adelaide, South Australia. …”
Publicado 2021
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575por Matsumoto-Sasaki, Machiko, Simizu, Kaoruko, Suzuki, Masanobu, Suzuki, Masaru, Kimura, Hirokazu, Nakamaru, Yuji, Ito, Yoichi M, Honma, Akihiro, Konno, Satoshi“…PATIENTS AND METHODS: This was a retrospective study of 42 patients with severe asthma treated with biologics at the Hokkaido University Hospital between 23(rd) June 2016 and 30(th) April 2021, when two biologics were available in Japan. …”
Publicado 2022
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576por Tomihari, Mizuki, Nobutoki, Yuko, Nakajima, Nagachika, Yanagawa, Masashi, Tagawa, Michihito, Hagiya, Koichi, Nomura, Tetsuro, Suwa, Yoshinori, Suzuki, Hiroshi“…Since swimmer puppies were observed infrequently but continuously among the Labrador retriever colony at the Hokkaido Guide Dogs for the Blind Association in Japan, based on their birth record and pedigree, factors related to the onset of swimmer puppy syndrome in Labrador retrievers were examined. …”
Publicado 2022
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577por Bragard, Claude, Baptista, Paula, Chatzivassiliou, Elisavet, Di Serio, Francesco, Gonthier, Paolo, Jaques Miret, Josep Anton, Justesen, Annemarie Fejer, Magnusson, Christer Sven, Milonas, Panagiotis, Navas‐Cortes, Juan A, Parnell, Stephen, Potting, Roel, Reignault, Philippe Lucien, Stefani, Emilio, Thulke, Hans‐Hermann, Van der Werf, Wopke, Vicent Civera, Antonio, Yuen, Jonathan, Zappalà, Lucia, Grégoire, Jean‐Claude, Malumphy, Chris, Kertesz, Virag, Maiorano, Andrea, MacLeod, Alan“…This species is present in Japan (except Hokkaidō), the Republic of Korea and 13 Chinese provinces. …”
Publicado 2022
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578por Matsubayashi, Shiho, Nakadai, Kazuhiro, Suzuki, Reiji, Ura, Tatsuya, Hasebe, Makoto, Okuno, Hiroshi G.“…Second, we monitored bitterns in an actual field environment using small microphone arrays (height = 12 cm; width = 8 cm), in the Sarobetsu Mire, Hokkaido Island, Japan. The simulation results showed that the spectral detectability was higher for larger microphone arrays, whereas the temporal detectability was higher for smaller microphone arrays. …”
Publicado 2022
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579por Kobayashi, Yoshitsugu, Takasaki, Ryuji, Fiorillo, Anthony R., Chinzorig, Tsogtbaatar, Hikida, Yoshinori“…One of these specimens, from the lower Campanian Osoushinai Formation in Nakagawa Town of Hokkaido Prefecture, was previously identified as a maniraptoran theropod dinosaur, possibly therizinosaur, but its taxonomic status remained unresolved. …”
Publicado 2022
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580por Handabile, Chimuka, Sekiya, Toshiki, Nomura, Naoki, Ohno, Marumi, Kawakita, Tomomi, Shingai, Masashi, Kida, Hiroshi“…In this study, we further examined and compared the immunological potency of monovalent WPV and SV of A/California/7/2009 (X-179A) (H1N1) pdm09 (CA/09) to generate immune responses against heterologous viruses, A/Singapore/GP1908/2015 (IVR-180) (H1N1) pdm09 (SG/15), and A/duck/Hokkaido/Vac-3/2007 (H5N1) (DH/07) in mice. Following challenge with a lethal dose of heterologous SG/15, lower virus titer in the lungs and milder weight loss were observed in WPV-vaccinated mice than in SV-vaccinated ones. …”
Publicado 2022
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