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601por Yamaguchi, Shigeru, Shiga, Tohru, Hirata, Kenji, Terasaka, Shunsuke, Kobayashi, Hiroyuki, Shimosegawa, Eku, Kagawa, Naoya, Hirayama, Ryuichi, Kinoshita, Manabu, Kijima, Haruhiko, Fujii, Masazumi, Ichikawa, Masahiro, Oriuchi, Noboru, Kuge, Yuji, Tamaki, Nagara“…We conducted multi-center prospective clinical trials using MET for drug approval in diagnosis of brain tumors[Methods] Two trials using 11C-MET PET were performed in Hokkaido University, Osaka University and Fukushima Medical University; 1) Diagnostic accuracy in differentiating tumor recurrence from radiation injury after radiotherapy in brain tumors, 2) The diagnostic efficacy in newly-diagnosed gliomas. 1) The patients with suspected brain tumor recurrence underwent MET and 18F-Fluorodeoxyglucose (FDG) PET. …”
Publicado 2020
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602por Suzuki, Ryusuke, Suzuki, Teppei, Tsuji, Shintaro, Fujiwara, Kensuke, Yamashina, Hiroko, Endoh, Akira, Ogasawara, Katsuhiko“…METHODS: First, we followed the website access log of Hokkaido University Hospital, which was collected from September 1, 2016, to August 31, 2017, and analyzed the access log using Google Analytics. …”
Publicado 2021
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603por Kuwatani, Masaki, Kawakubo, Kazumichi, Sugimori, Kazuya, Inoue, Hiroyuki, Kamada, Hideki, Ishiwatari, Hirotoshi, Kato, Shin, Iwashita, Takuji, Yoshida, Makoto, Hashimoto, Shinichi, Itonaga, Masahiro, Mizukami, Yusuke, Nomura, Yusuke, Katanuma, Akio, Sakamoto, Naoya“…ETHICS AND DISSEMINATION: This study has been approved by the institutional review board of Hokkaido University Hospital. The results will be submitted for presentation at an international medical conference and published in a peer-reviewed journal. …”
Publicado 2021
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604por Fukuda, Yuya, Tsugawa, Takeshi, Nagaoka, Yoshinobu, Ishii, Akira, Nawa, Tomohiro, Togashi, Atsuo, Kunizaki, Jun, Hirakawa, Satoshi, Iida, Junya, Tanaka, Toju, Kizawa, Toshitaka, Yamamoto, Dai, Takeuchi, Ryoh, Sakai, Yoshiyuki, Kikuchi, Masayoshi, Nagai, Kazushige, Asakura, Hirofumi, Tanaka, Rina, Yoshida, Masaki, Hamada, Ryo, Kawasaki, Yukihiko“…METHODS: We conducted a multicenter, prospective survey for hospitalized pediatric patients in 18 hospitals in Hokkaido Prefecture, Japan, from July 2019 to February 2021. …”
Publicado 2021
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605por Shiratori-Aso, Satoka, Nakazawa, Daigo, Nishio, Saori, Ueda, Yusho, Eguchi, Mina, Yokoyama, Ai, Yoshikawa, Junpei, Kudo, Takashi, Watanabe-Kusunoki, Kanako, Takeda-Otera, Sayo, Yamamoto, Junya, Matsuoka, Naoko, Kaneshima, Nobuharu, Hattanda, Fumihiko, Iwasaki, Sari, Tsuji, Takahiro, Fukasawa, Yuichiro, Atsumi, Tatsuya“…PARTICIPANTS: 62 patients were diagnosed of TIN from 2005 to April 2018 at Hokkaido University Hospital. Among them, 30 patients were diagnosed with autoimmune TIN and treated with corticosteroids. …”
Publicado 2022
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606por Tanaka, Yoshimasa, Nishikawa, Megumi, Kamisaki, Kaho, Hachiya, Saki, Nakamura, Moeka, Kuwazuru, Takahiro, Tanimura, Susumu, Soyano, Kiyoshi, Takeda, Kohsuke“…Nagasaki Prefecture has many islands and is surrounded by seas, straits, gulfs, bays, and coves, giving it the second longest coastline in Japan after Hokkaido. We have collected more than 20,000 marine microbes and have been preparing an original marine microbial extract library, which contains small and mid-size biomolecules that may penetrate cell membranes and interfere with the intracellular protein–protein interaction involved in the development of autoinflammatory diseases such as familial Mediterranean fever. …”
Publicado 2022
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607por Saito, Rika, Kawamoto, Yasuyuki, Nishida, Mutsumi, Iwai, Takahito, Kikuchi, Yasuka, Yokota, Isao, Takagi, Ryo, Yamamura, Takahiro, Ito, Ken, Harada, Kazuaki, Yuki, Satoshi, Komatsu, Yoshito, Sakamoto, Naoya“…We investigated the usefulness of the Hokkaido ultrasonography-based scoring system with 10 ultrasonographic parameters (HokUS-10) and SWE in diagnosing oxaliplatin-induced SOS early. …”
Publicado 2022
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608por Liniger, Matthias, Moulin, Hervé R, Sakoda, Yoshihiro, Ruggli, Nicolas, Summerfield, Artur“…This contrasted with an NS1 mutant Yama virus (Yama-NS1(A144V)) and with the attenuated H5N1 AIV A/duck/Hokkaido/Vac-1/04 (Vac) carrying the haemagglutinin (HA) of the Yama virus (Vac-Yama/HA), that both induced type I IFN in these cells. …”
Publicado 2012
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609por Dapat, Isolde C., Dapat, Clyde, Baranovich, Tatiana, Suzuki, Yasushi, Kondo, Hiroki, Shobugawa, Yugo, Saito, Reiko, Suzuki, Hiroshi“…For viruses that circulated in 2010–2011, strain predominance varied among prefectures. In Hokkaido, Niigata, Gunma and Nagasaki, A(H3N2) viruses (A/Perth/16/2009-like) were predominant whereas, in Kyoto, Hyogo and Osaka, A(H1N1)pdm09 viruses (A/New_York/10/2009-like) were predominant. …”
Publicado 2012
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610por Kawamoto, Yasuyuki, Komatsu, Yoshito, Yuki, Satoshi, Sawada, Kentaro, Muranaka, Tetsuhito, Harada, Kazuaki, Nakatsumi, Hiroshi, Fukushima, Hiraku, Ishiguro, Atsushi, Dazai, Masayoshi, Hatanaka, Kazuteru, Nakamura, Michio, Iwanaga, Ichiro, Uebayashi, Minoru, Sogabe, Susumu, Kobayashi, Yoshimitsu, Miyagishima, Takuto, Ono, Kota, Sakamoto, Naoya, Sakata, Yuh“…TRIAL REGISTRATION: This study is performed at institutes that participate in Hokkaido Gastrointestinal Cancer Study Group (HGCSG) and registered as UMIN000016788. …”
Publicado 2017
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611por Kanazawa, Jun, Kitazawa, Haruna, Masuko, Hironori, Yatagai, Yohei, Sakamoto, Tohru, Kaneko, Yoshiko, Iijima, Hiroaki, Naito, Takashi, Saito, Takefumi, Noguchi, Emiko, Konno, Satoshi, Nishimura, Masaharu, Hirota, Tomomitsu, Tamari, Mayumi, Hizawa, Nobuyuki“…METHODS: This case-control study, which was conducted at the University of Tsukuba, Japan, included a total of 2709 adults from the Tsukuba genome-wide association study (GWAS) cohort (734 healthy volunteers and 237 asthma patients), the Tsukuba replication cohort (375 healthy adult volunteers and 381 adult asthma patients), and the Hokkaido replication cohort (554 healthy adult volunteers and 428 adult asthma patients). …”
Publicado 2019
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612por Zhao, Kun-Kun, Landrein, Sven, Barrett, Russell L., Sakaguchi, Shota, Maki, Masayuki, Mu, Wei-Xue, Yang, Ting, Zhu, Zhi-Xin, Liu, Huan, Wang, Hua-Feng“…During the Last Glacial Maximum (LGM) period after the Tertiary, Diabelia was potentially widely distributed in southeastern China, the continental shelf of the East China Sea and Japan (excluding Hokkaido). After LGM, all populations in China have disappeared except those in Zhejiang which may represent a Glacial refuge. …”
Publicado 2019
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613por Chon, Irina, Saito, Reiko, Hibino, Akinobu, Yagami, Ren, Dapat, Clyde, Odagiri, Takashi, Kondo, Hiroki, Sato, Isamu, Kimura, Shinji, Kawashima, Takashi, Kodo, Naoki, Masaki, Hironori, Asoh, Norichika, Tsuchihashi, Yoshiko, Zaraket, Hassan, Shobugawa, Yugo“…Nasopharyngeal swabs were collected from outpatients who visited clinics with influenza-like illness (ILIs) in Hokkaido, Niigata, Gunma and Nagasaki prefectures. …”
Publicado 2019
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614“…RESULTS: The heritability of the β-eudesmol/hinesol content ratio in A. lancea was evaluated through the cultivation of clonal lines of A. lancea in both different years (2016, 2017) and locations (Hokkaido, Ibaraki). Correlations between β-eudesmol and hinesol contents were identified in all clonal lines, with high correlation coefficients (r = 0.73–0.99). …”
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615por Yokomitsu, Kengo, Irie, Tomonari, Sekiguchi, Mayu, Shimizu, Ayako, Matsuoka, Hirofumi, Merry, Sally Nicola, Stasiak, Karolina“…RESULTS: This study received funding from The Research Institute of Personalized Health Sciences, Health Sciences University of Hokkaido, and obtained institutional review board approval in September 2019. …”
Publicado 2020
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616por Sekizaki, Tomonori, Kameda, Hiraku, Cho, Kyu Yong, Akinobu, Nakamura, Takahashi, Kiyohiko, Wada, Norio, Takeuchi, Jun, Nagai, So, Miyoshi, Hideaki, Atsumi, Tatsuya“…The trial was approved by the institutional review board of Hokkaido University Hospital. [Results] Eighty-three patients were enrolled in the study, and they were divided into an exacerbation group (n = 18) and a non-exacerbation group (n = 65). …”
Publicado 2020
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617por Shimizu, Tomohiro, Yokota, Shunichi, Kimura, Yosuke, Asano, Tsuyoshi, Shimizu, Hirokazu, Ishizu, Hotaka, Iwasaki, Norimasa, Takahashi, Daisuke“…METHODS: Between January 2010 and December 2019, 238 patients in whom band pattern of the femoral head were observed on MRI visited Hokkaido University Hospital. Among these patients, 44 hips in 41 patients were diagnosed with SIF and eligible for this retrospective study. …”
Publicado 2020
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618por Yonemoto, Naohiro, Suzuki, Shunji, Sekizawa, Akihiko, Hoshi, Shinichi, Sagara, Yoko, Itahashi, Kazuo“…Regarding the positive rates, some areas (Hokkaido/Tohoku, Kanto, and Chugoku/Shikoku) exhibited decreases or increases by facility type. …”
Publicado 2020
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619por Inoue, Masaki, Shimizu, Yuichi, Ishikawa, Marin, Abiko, Satoshi, Shimoda, Yoshihiko, Tanaka, Ikko, Kinowaki, Sayoko, Ono, Masayoshi, Yamamoto, Keiko, Ono, Shoko, Sakamoto, Naoya“…METHODS: We conducted an exploratory retrospective study using new specimens, and we enrolled 145 patients who underwent endoscopic resection for superficial ESCC and had been observed for more than two years by both physical examination and endoscopic examination in Hokkaido University Hospital. Saliva was collected to analyze genetic polymorphisms of ADH1B/ALDH2. …”
Publicado 2020
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620por Komatsu, Masahiro, Kurihara, Keigo, Saito, Susumu, Domae, Mana, Masuya, Naoki, Shimura, Yuta, Kajiyama, Shunichiro, Kanda, Yuna, Sugizaki, Kouki, Ebina, Kouji, Ikeda, Osamu, Moriwaki, Yudai, Atsumi, Naohiro, Abe, Katsuyoshi, Maruyama, Tadashi, Watanabe, Satoshi, Nishino, Hiroshi“…The aim of this study was to establish a method to reduce the numbers of large moths that are attracted to lights in the rest areas of expressways in Hokkaido based on the results of research on their behavioral ecology and physiology. …”
Publicado 2020
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