Mostrando 21 - 40 Resultados de 2,739 Para Buscar '"Homer"', tiempo de consulta: 0.31s Limitar resultados
  1. 21
    “…The cellular localization of the glutamatergic receptor subtypes, as well as their signaling efficiency and function, are highly dependent upon discrete functional constituents of the postsynaptic density, including the Homer family of scaffolding proteins. The consequences of repeated alcohol administration on the expression of the Homer family proteins demonstrate a crucial and active role, particularly for the expression of Homer2 isoform, in regulating alcohol-induced behavioral and cellular neuroplasticity. …”
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    “…However, Homer participates in many additional known interactions whose activity-dependence is unclear. …”
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    “…Reduced Homer crosslinking at the NMJ consequent to increased Homer1a and/or reduced Homer2 may contribute to muscle-type specific atrophy resulting from microgravity and HU disuse suggesting mutual mechanisms.…”
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  4. 24
    “…BACKGROUND: Homer proteins are post-synaptic density proteins with known functions in receptor trafficking and calcium homeostasis. …”
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    “…Surprisingly, we found that the Homer/Flotillin interaction and its localization to the nucleus are conserved in metazoan astrocytes. …”
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    “…Homer protein was identified based on its rapid induction in rat hippocampal granule cell neurons following excitatory synaptic activity. …”
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  10. 30
    por Zhang, Fan, Chen, Jake Y
    Publicado 2011
    “…RESULTS: We designed an integrated Human Organ-specific Molecular Electronic Repository (HOMER, http://bio.informatics.iupui.edu/homer), defining human organ-specific genes/proteins, based on five criteria: 1) comprehensive organ coverage; 2) gene/protein to disease association; 3) disease-organ association; 4) quantification of organ-specificity; and 5) cross-linking of multiple available data sources. …”
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  11. 31
    “…The activity-induced expression of short Homer1 isoforms, Homer1a and Ania-3, is thought to be related to processes of learning and memory. …”
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  12. 32
    por Chung, Geehoon, Kim, Sang Jeong
    Publicado 2017
    “…The issues concerning Homer1a mechanism in the constitutive activity of group I mGlus and recent findings regarding the significant role of β-arrestin in sustained GPCR activity are also discussed. …”
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  13. 33
    por Chicco, Maria, Tebala, Giovanni D.
    Publicado 2020
    “…PURPOSE: Homer’s Iliad reports detailed descriptions of war traumas, with precise anatomical references, so that the Iliad can be considered the first trauma registry. …”
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    “…Earlier studies of Homer1 gene knock-out (KO) mice indicated active, but distinct, roles for IEG and constitutively expressed Homer1 gene products in regulating cognitive, emotional, motivational and sensorimotor processing, as well as behavioral and neurochemical sensitivity to cocaine. …”
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