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  1. 2261
    “…The new updated and enhanced version allows detailed investigation of AU, GU and U-rich elements (ARE, GRE, URE) in the transcriptome of Homo sapiens, Mus musculus, Danio rerio, Caenorhabditis elegans and Drosophila melanogaster. …”
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    AREsite2: an enhanced database for the comprehensive investigation of AU/GU/U-rich elements
  2. 2262
    “…Finally, we demonstrate that replacement of the TD with a synthetic tetramerizing coiled coil sequence supports homo-oligomerization and normal VASP subcellular localization.…”
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    Selectivity in subunit composition of Ena/VASP tetramers
  3. 2263
    “…Using optoRAF, vemurafenib was identified as paradoxical activator of BRAF and CRAF homo- and heterodimers. Dabrafenib enhanced activity of light-stimulated CRAF at low dose and inhibited CRAF signaling at high dose. …”
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    Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors
  4. 2264
    “…The globular structure of the C. elegans separase–securin complex contrasts with the more elongated structure previously described for the Homo sapiens complex, which could represent a different functional state of the complex, suggesting a mechanism for the regulation of separase activity through conformational change.…”
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    A closed conformation of the Caenorhabditis elegans separase–securin complex
  5. 2265
    “…Fur loss is most likely associated with the exploitation of open habitats at much lower altitudes at a much later date by the genus Homo.…”
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    Bipedality and hair loss in human evolution revisited: The impact of altitude and activity scheduling
  6. 2266
    por Byeon, Boseon, Kovalchuk, Igor
    Publicado 2016
    “…To address this question in greater detail, we analyze NGS data from four organisms with different GC content, Plasmodium falciparum (19.39%), Arabidopsis thaliana (36.03%), Homo sapiens (40.91%) and Streptomyces coelicolor (72.00%). …”
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    Pattern Recognition on Read Positioning in Next Generation Sequencing
  7. 2267
    “…Age had adverse effects on future cognition, and these were largely mediated through δ, independently of education, ethnicity, gender, depression ratings, serum homo-cysteine levels, hemoglobin A1c, and apolipoprotein e4 status. …”
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    Aging is a weak but relentless determinant of dementia severity
  8. 2268
    por Trosko, James E.
    Publicado 2016
    “…Within the hierarchical and cybernetic concepts, differentiated by neurons organized in the brain of the Homo sapiens, the conscious mind led to language, abstract ideas, technology, myth-making, scientific reasoning, and moral decision–making, i.e., the creation of culture. …”
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    Evolution of Microbial Quorum Sensing to Human Global Quorum Sensing: An Insight into How Gap Junctional Intercellular Communication Might Be Linked to the Global Metabolic Disease Crisis
  9. 2269
    “…This study was carried out for Homo sapiens single variation (SNPs/Indels) in BRAF gene through coding/non-coding regions. …”
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    Bioinformatics Approach for Prediction of Functional Coding/Noncoding Simple Polymorphisms (SNPs/Indels) in Human BRAF Gene
  10. 2270
    “…The regulation of MST1/2 includes both homo- and heterodimerization, mediated by helical SARAH domains, though the underlying molecular interaction mechanism is unclear. …”
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    SARAH Domain-Mediated MST2-RASSF Dimeric Interactions
  11. 2271
    “…Biodegradable polymers, especially aliphatic polyesters (polylactide/polyglycolide/polycaprolactone homo- and copolymers), have a large range of medical applications including delivery systems, scaffolds, or stents for the treatment of cardiovascular diseases. …”
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    Modelling pH-Optimized Degradation of Microgel-Functionalized Polyesters
  12. 2272
    “…In collagens three polypeptides form a unique triple-helical structure with a one-residue stagger to fit every third glycine residue in the inner core without disturbing the poly-proline type II helical conformation of each chain. There are homo- and hetero-trimeric types of collagen consisting of one, two or three distinct chains. …”
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    Structural insight for chain selection and stagger control in collagen
  13. 2273
    “…This platform can accommodate a large variety of organic ligands and homo- or hetero-metallic clusters, which allows for extraordinary tunability in gas sorption properties. …”
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    An ultra-tunable platform for molecular engineering of high-performance crystalline porous materials
  14. 2274
    “…Optimal conditions for the slow release of the boronic acid using KOH as the base in biphasic THF/water mixtures enables the thienyl MIDA boronate esters to be extremely effective homo-bifunctionalized (AA-type) monomers in Suzuki–Miyaura copolymerizations with dibromo-heteroarenes (BB-type monomers). …”
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    A General Protocol for the Polycondensation of Thienyl N-Methyliminodiacetic Acid Boronate Esters To Form High Molecular Weight Copolymers
  15. 2275
    “…Other homologs include Rn-GM130 (Rattus norvegicus); Hs-GM130 (Homo sapiens), Dm-golgin90 (Drosophila melanogaster), Ce-golgin107 (Caenorhabditis elegans) and Bm-golgin (Brugia malayi) PBS: phosphate buffered saline PBST: phosphate buffered saline containing 0.05% Tween-20 TBST: Tris buffered saline containing 0.05% Tween-20…”
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    A new member of the GM130 golgin subfamily is expressed in the optic lobe anlagen of the metamorphosing brain of Manduca sexta
  16. 2276
    “…Under the hypothesis that functionally related genes tend to share common genetic interaction partners, we evaluate a computational approach to predict genetic interactions in Homo sapiens, Drosophila melanogaster, and Saccharomyces cerevisiae. …”
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    Predictability of Genetic Interactions from Functional Gene Modules
  17. 2277
    “…With the example of a novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitor, we demonstrate that the CRISPR/Cas9 system enables the generation of transient homo- and heterozygous deletion libraries and allows for the identification of efficacy targets and pathways mediating hypersensitivity and resistance relevant to the compound mechanism of action.…”
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    Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells
  18. 2278
    “…Here, we show that the isolated HsCCD and HsPB3 domains form a mixture of homo-multimers in vitro, but these readily dissociate when mixed to form the previously described 1:1 HsCCD:HsPB3 complex. …”
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    A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies
  19. 2279
    “…C–H bond activation and homo-coupling of the precursors is achieved upon thermal activation. …”
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    On-surface synthesis of aligned functional nanoribbons monitored by scanning tunnelling microscopy and vibrational spectroscopy
  20. 2280
    por Williams, Adrian C, Hill, Lisa J
    Publicado 2017
    “…This culminated in the 3-million-year evolution of Homo sapiens and our overall demographic success. …”
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    Meat and Nicotinamide: A Causal Role in Human Evolution, History, and Demographics
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