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  1. 2541
    “…Retinoschisin is predominantly expressed and secreted from photoreceptor cells as a homo-oligomer protein; it then associates with the surface of retinal cells and maintains the retina cellular architecture. …”
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    Regulation of Retinoschisin Secretion in Weri-Rb1 Cells by the F-Actin and Microtubule Cytoskeleton
  2. 2542
    “…Two organisms are currently supported: Homo sapiens and Mus musculus. The intuitive user interface and large database make mirConnX a useful tool for clinical scientists for hypothesis generation and explorations. mirConnX is freely available for academic use at http://www.benoslab.pitt.edu/mirconnx.…”
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    mirConnX: condition-specific mRNA-microRNA network integrator
  3. 2543
    “…In this study, we explored the relationship between CpG islands methylation and signatures of selective pressure in Homo Sapiens, using a computational biology approach. …”
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    CpG Islands Undermethylation in Human Genomic Regions under Selective Pressure
  4. 2544
    por Rawal, Kamal, Ramaswamy, Ram
    Publicado 2011
    “…We have studied the genomes of Homo sapiens, Mus musculus, Drosophila melanogaster and Entamoeba histolytica via a protocol whereby DNASCANNER is used to identify a common set of statistically important signals flanking the insertion sites in the various genomes. …”
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    Genome-wide analysis of mobile genetic element insertion sites
  5. 2545
    “…Using FRET analysis, we show that CALM-AF10 has a propensity to homo-oligomerize, raising the possibility that the function of endocytic proteins involved in chimeric fusions may be to provide dimerization properties, a recognized mechanism for unleashing oncogenic properties of chimeric transcription factors, rather than disrupting the internalization of growth factor receptors.…”
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    The Clathrin-Binding Domain of CALM-AF10 Alters the Phenotype of Myeloid Neoplasms in Mice
  6. 2546
    por Yu, Linliang, Lu, Wei, Wei, Yinan
    Publicado 2011
    “…The multidrug transporter AcrB in Escherichia coli exists and functions as a homo-trimer. The assembly process of obligate membrane protein oligomers, including AcrB, remains poorly understood. …”
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    AcrB Trimer Stability and Efflux Activity, Insight from Mutagenesis Studies
  7. 2547
    “…For microarray analysis the febit biochip "Geniom(® )Biochip MPEA homo-sapiens" was used. Total RNA was isolated from FFPE tissue sections and 1100 different miRNAs were analyzed. …”
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    MiRNA expression patterns predict survival in glioblastoma
  8. 2548
    “…We gathered 839 protein structural pairs of ligand-free and ligand-bound states from monomeric or homo-dimeric proteins, and constructed the Protein Structural Change DataBase (PSCDB). …”
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    PSCDB: a database for protein structural change upon ligand binding
  9. 2549
    “…METHODOLOGY/PRINCIPAL FINDINGS: Thermodynamic profiles of the associations of dimeric βA3 and βB1 and tetrameric βB1/βA3 were measured using sedimentation equilibrium. The homo- and heteromolecular associations of βB1 crystallin are dominated by exothermic enthalpy (−13.3 and −24.5 kcal/mol, respectively). …”
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    βB1-Crystallin: Thermodynamic Profiles of Molecular Interactions
  10. 2550
    por Pedone, Francesco, Santoni, Daniele
    Publicado 2012
    “…Mean helical rise profiles obtained by using maps of positioned nucleosomes of the Drosophila melanogaster and Plasmodium falciparum genomes, as well as Homo sapiens chromosome 20 confirm that nucleosomes are mainly located where the mean helical rise reaches its largest values.…”
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    Preferential Nucleosome Occupancy at High Values of DNA Helical Rise
  11. 2551
    “…The far-red fluorescent protein HcRed, which is fluorescent only in a dimer form, can be used to promote the homo-dimerisation of target proteins, and thereby yield useful information about biological processes. …”
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    HcRed, a Genetically Encoded Fluorescent Binary Cross-Linking Agent for Cross-Linking of Mitochondrial ATP Synthase in Saccharomyces cerevisiae
  12. 2552
    “…Cells exhibiting this inhibition phenotype (IP) prevent the plating of homo-immune and hybrid hetero-immune lambdoid phages. …”
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    A CI-Independent Form of Replicative Inhibition: Turn Off of Early Replication of Bacteriophage Lambda
  13. 2553
    “…IMP currently supports seven organisms (Homo sapiens, Mus musculus, Rattus novegicus, Drosophila melanogaster, Danio rerio, Caenorhabditis elegans and Saccharomyces cerevisiae), does not require any registration or installation and is freely available for use at http://imp.princeton.edu.…”
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    IMP: a multi-species functional genomics portal for integration, visualization and prediction of protein functions and networks
  14. 2554
    “…Moreover, the efficiency of ubiquitination reactions can be altered by the formation of homo- and heterotypic E3-RING complexes. To establish the prevalence and nature of binary E3-RING/E3-RING interactions systematic yeast two-hybrid screens were performed to test 7269 potential interactions between 124 human E3-RING proteins. …”
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    Systematic Analysis of Dimeric E3-RING Interactions Reveals Increased Combinatorial Complexity in Human Ubiquitination Networks
  15. 2555
    por Ryan, Timothy M., Shaw, Colin N.
    Publicado 2012
    “…High-resolution computed tomography images were collected from the humeral and femoral heads of 115 individuals from eight anthropoid primate genera (Alouatta, Homo, Macaca, Pan, Papio, Pongo, Trachypithecus, Symphalangus). …”
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    Unique Suites of Trabecular Bone Features Characterize Locomotor Behavior in Human and Non-Human Anthropoid Primates
  16. 2556
    por Yorimitsu, Tomohiro, Sato, Ken
    Publicado 2012
    “…We also find that purified Sec16 alone can self-assemble into homo-oligomeric complexes on a planar lipid membrane. …”
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    Insights into structural and regulatory roles of Sec16 in COPII vesicle formation at ER exit sites
  17. 2557
    “…By expressing human eEF1A in T. brucei, we now show that EPG attachment to eEF1A is evolutionarily conserved between T. brucei and Homo sapiens. In contrast, S. cerevisiae eEF1A, which has been shown to lack EPG is not modified in T. brucei. …”
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    Eukaryotic Translation Elongation Factor 1A (eEF1A) Domain I from S. cerevisiae Is Required but Not Sufficient for Inter-Species Complementation
  18. 2558
    “…All the gene products involved in different metabolic pathways of CA-MRSA in KEGG database were searched against the proteome of Homo sapiens using the BLASTp program and the threshold of E-value was set to as 0.001. …”
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    Potential therapeutic drug target identification in Community Acquired-Methicillin Resistant Staphylococcus aureus (CA-MRSA) using computational analysis
  19. 2559
    “…The title compound, [Cu(3)(C(19)H(18)Cl(2)N(2)O(2))(2)(CH(3)CO(2))(2)], is a linear homo-trinuclear Cu(II) complex. The central Cu(II) atom is located on a centre of inversion and has a distorted octa­hedral coordination environment formed by six O atoms from two tetra­dentate Schiff base ligands and two bridging acetate ligands. …”
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    Di-μ(2)-acetato-1:2κ(2) O:O′;2:3κ(2) O:O′-bis­{μ(2)-4,4′-dichloro-2,2′-[2,2-dimethyl­propane-1,3-diylbis(nitrilo­methanylyl­idene)]diphenolato}-1:2κ(6) O,N,N′,O′:O,O′;2:3κ(6) O,O′:O,N,N′,O′-tricopper(II)
  20. 2560
    “…We performed a genome-level computational study of sequence and structure similarity, the latter using crystal structures and models, of the proteases of Homo sapiens and the human parasite Trypanosoma brucei. …”
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    A Global Comparison of the Human and T. brucei Degradomes Gives Insights about Possible Parasite Drug Targets
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