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  1. 2561
    “…Finally, the few reports on expression, localization, enzymatic activity, and physiological roles in the model organisms Drosophila melanogaster, Caenorhabditis elegans, and Homo sapiens are critically reviewed. Roles attributed to peroxidasins include antimicrobial defense, extracellular matrix formation, and consolidation at various developmental stages. …”
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    Molecular Evolution, Structure, and Function of Peroxidasins
  2. 2562
    “…To examine functional robustness of networks with varying input, we enhanced an existing RMT implementation for improved scalability and tested functional robustness of human (Homo sapiens), rice (Oryza sativa) and budding yeast (Saccharomyces cerevisiae). …”
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    Massive-Scale Gene Co-Expression Network Construction and Robustness Testing Using Random Matrix Theory
  3. 2563
    “…In this study we test these hypotheses in a sample of adult specimens belonging to three extant hominid genera (Homo, Pan and Gorilla). Intraspecific variation and covariation patterns are analyzed using geometric morphometric methods and multivariate statistics, such as partial least squared on three-dimensional landmarks coordinates. …”
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    Facial Orientation and Facial Shape in Extant Great Apes: A Geometric Morphometric Analysis of Covariation
  4. 2564
    “…Critical points of SST/SST receptor biology, such as signaling pathways of individual receptor subtypes, homo- and heterodimerization, trafficking, and cross-talk with growth factor receptors, have been extensively studied, although functions associated with several pathological conditions, including cancer, are still not completely unraveled. …”
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    Peptide Receptor Targeting in Cancer: The Somatostatin Paradigm
  5. 2565
    “…Here we compare the structure and stability of homo and heteropolymeric fibrils formed from human β(2)-microglobulin and its truncated variant ΔN6. …”
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    Expanding the Repertoire of Amyloid Polymorphs by Co-polymerization of Related Protein Precursors
  6. 2566
    “…RESULTS: We applied our algorithm to several PPI (Protein-Protein Interaction) networks of Saccharomyces cerevisiae and Homo sapiens, and validated our results using public databases of protein complexes. …”
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    Improved method for protein complex detection using bottleneck proteins
  7. 2567
    “…Molecular descriptors, dipole moment, electronegativity, total energy at 0 K, entropy at 298 K, HOMO and LUMO energies obtained from DFT calculations provide valuable information and have a significant role in the assessment of carbonic anhydrase (CA-II) inhibitory activity of the compounds. …”
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    A DFT-Based QSARs Study of Acetazolamide/Sulfanilamide Derivatives with Carbonic Anhydrase (CA-II) Isozyme Inhibitory Activity
  8. 2568
    “…These new data point to diversity of patterns of facial growth in fossil Homo. The similarities in facial growth in H. antecessor and H. sapiens suggest that one key developmental change responsible for the characteristic facial morphology of modern humans can be traced back at least to H. antecessor.…”
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    Facial Morphogenesis of the Earliest Europeans
  9. 2569
    “…Seven organisms are currently supported (Arabidopsis thaliana, Caenorhabditis elegans, Drosophila melanogaster, Mus musculus, Homo sapiens, Rattus norvegicus and Saccharomyces cerevisiae), and hundreds of data sets have been collected from GEO, BioGRID, IRefIndex and I2D, as well as organism-specific functional genomics data sets. …”
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    GeneMANIA Prediction Server 2013 Update
  10. 2570
    “…The BTB-BACK domains are important for Keap1 homo-dimerization as well as to interact with Cullin-3 for Nrf2 degradation. …”
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    Analysis of dimerization of BTB-IVR domains of Keap1 and its interaction with Cul3, by molecular modeling
  11. 2571
    “…Herein, we report that prior ligation of TLR2, an event previously shown to induce “homo” or “hetero” tolerance, strongly “primes” macrophages for increased Type I IFN production in response to subsequent TLR/RLR signaling. …”
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    Reprogramming of Murine Macrophages through TLR2 Confers Viral Resistance via TRAF3-Mediated, Enhanced Interferon Production
  12. 2572
    “…The role of receptor dimerization in oncogenic EGFRvIII mutant activation is not completely understood and the molecular details of EGFRvIII interactions within homo-dimers and hetero-dimers are not elucidated yet. …”
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    Asymmetric kinase dimer formation is crucial for the activation of oncogenic EGFRvIII but not for ERBB3 phosphorylation
  13. 2573
    “…Using this approach, we performed a systematical comparison of mutation regularities within 2–4 bp contexts in Mus musculus and Homo sapiens and uncovered that even closely related organisms may have notable differences in context-dependent mutation regularities.…”
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    Comparative Analysis of Context-Dependent Mutagenesis Using Human and Mouse Models
  14. 2574
    “…The N-termini of major UNC-13/Munc13 isoforms contain a non-calcium binding C(2)A domain that mediates protein homo- or hetero-meric interactions. Here, we show that the C(2)A domain of Caenorhabditis elegans UNC-13 regulates release probability of evoked release and its precise active zone localization. …”
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    Position of UNC-13 in the active zone regulates synaptic vesicle release probability and release kinetics
  15. 2575
    “…P2X receptors are ATP-gated non-selective cation channels involved in many different physiological processes, such as synaptic transmission, inflammation, and neuropathic pain. They form homo- or heterotrimeric complexes and contain three ATP-binding sites in their extracellular domain. …”
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    Exploring the ATP-binding site of P2X receptors
  16. 2576
    “…Moreover, the cytosolic region of TMCC1 formed homo- or hetero-dimers or oligomers with other TMCC proteins and interacted with ribosomal proteins. …”
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    Transmembrane and Coiled-Coil Domain Family 1 Is a Novel Protein of the Endoplasmic Reticulum
  17. 2577
    “…The signalling output from EGFR is complicated given that other ErbB proteins are often additionally expressed and activated in the same cell, resulting in formation of homo-and/or heterodimers. In particular, association of EGFR with ErbB2 prevents its down-regulation, underscoring the importance of the cellular background for EGFR effects. …”
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    Epidermal growth factor receptor and cancer: control of oncogenic signalling by endocytosis
  18. 2578
    “…Therefore, in addition to Flores harboring unusual diversity in the form of Homo floresiensis, dwarfed stegodons and giant rats, this island appears to be the homeland of R. exulans.…”
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    Molecular Genetic Evidence for the Place of Origin of the Pacific Rat, Rattus exulans
  19. 2579
    por Shen, Lei
    Publicado 2011
    “…Polymers with different architectures, such as homo- and co-polymer, hyperbranched polymer, and polymeric nanogel, have been used to anchor and protect QDs. …”
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    Biocompatible Polymer/Quantum Dots Hybrid Materials: Current Status and Future Developments
  20. 2580
    “…How human language arose is a mystery in the evolution of Homo sapiens. Miyagawa et al. (2013) put forward a proposal, which we will call the Integration Hypothesis of human language evolution, that holds that human language is composed of two components, E for expressive, and L for lexical. …”
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    The integration hypothesis of human language evolution and the nature of contemporary languages
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