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241
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242por Gaber, Aljaž, Kim, Seung Joong, Kaake, Robyn M., Benčina, Mojca, Krogan, Nevan, Šali, Andrej, Pavšič, Miha, Lenarčič, Brigita“…Here, we first show that EpCAM monomers do not associate into oligomers that would resemble an inter-cellular homo-oligomer, capable of mediating cell-cell adhesion, by using SAXS, XL-MS and bead aggregation assays. …”
Publicado 2018
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243“…Furthermore, both homo- and cross-couplings of a series of alkaloids, amino acids and steroids exemplify application of this protocol in the functionalization of biologically active molecules.…”
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245por Rao, Timsi, Longerich, Simonne, Zhao, Weixing, Aihara, Hideki, Sung, Patrick, Xiong, Yong“…The Pseudomonas aeruginosa bacterial FAN1 and human FAN1 (hFAN1) missing a flexible loop are monomeric, while intact hFAN1 is homo-dimeric in structure. Importantly, the monomeric and dimeric forms of FAN1 exhibit very different DNA binding modes. …”
Publicado 2018
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246por Ostuni, Mariano A., Hermand, Patricia, Saindoy, Emeline, Guillou, Noëlline, Guellec, Julie, Coens, Audrey, Hattab, Claude, Desuzinges-Mandon, Elodie, Jawhari, Anass, Iatmanen-Harbi, Soria, Lequin, Olivier, Fuchs, Patrick, Lacapere, Jean-Jacques, Combadière, Christophe, Pincet, Frédéric, Deterre, Philippe“…The analysis of CX3CL1 clusters using native electrophoresis and single molecule fluorescence kinetics shows that CX3CL1 is a homo-oligomer of 3 to 7 monomers. Fluorescence recovery after photobleaching assays reveal that the CX3CL1-transmembrane domain peptide self-associates in both cellular and acellular lipid environments, while its random counterpart (i.e. peptide with the same residues in a different order) does not. …”
Publicado 2020
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247por Vichi, Stefania, Mayer, Morgana N., León-Cárdenas, Maria G., Quintanilla-Casas, Beatriz, Tres, Alba, Guardiola, Francesc, Batlle, Ignasi, Romero, Agustí“…On this basis, volatile metabolites related to almond bitterness were investigated by Solid Phase Microextraction-Gas Chromatography-Mass Spectrometry coupled to univariate and multivariate statistics on 244 homo- and heterozygous samples from 42 different cultivars. …”
Publicado 2020
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248por Wen, Hai-Jun, Liu, Feng-Liang, Huang, Ming-Xing, Luo, Rong-Hua, He, Wen-Bin, Feng, Jing, Chen, Fang-Liang, Cai, Qi-Chun, Ma, Hua-Juan, Yang, Zi-Feng, Zhou, Xi, Shang, You, Lyu, Xue-Mei, Zhang, Ding-Yu, Xiao, Fei, Shan, Hong, He, Jian-Xing, Zheng, Yong-Tang, Wu, Chung-IEnlace del recurso
Publicado 2020
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249por Irimia-Dominguez, Jose, Sun, Chen, Li, Kunpeng, Muhoberac, Barry B., Hallinan, Grace I., Garringer, Holly J., Ghetti, Bernardino, Jiang, Wen, Vidal, RubenEnlace del recurso
Publicado 2020
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250por De Simone, Giovanna, di Masi, Alessandra, Ciaccio, Chiara, Coletta, Massimo, Ascenzi, Paolo“…In this study, we show that NO scavenging occurs through the reductive nitrosylation of ferric Mycobacterium tuberculosis and Homo sapiens nitrobindins (Mt-Nb(III) and Hs-Nb(III), respectively). …”
Publicado 2020
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251“…Protein homo-oligomerization is a very common phenomenon, and approximately half of proteins form homo-oligomeric assemblies composed of identical subunits. …”
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252por Andersson, Åke, Poline, Mathias, Houthuijs, Kas J., van Outersterp, Rianne E., Berden, Giel, Oomens, Jos, Zhaunerchyk, Vitali“…[Image: see text] We investigate gas-phase structures of homo- and heterochiral asparagine proton-bound dimers with infrared multiphoton dissociation (IRMPD) spectroscopy and quantum-chemical calculations. …”
Publicado 2021
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254por Brumm, Adam, Bulbeck, David, Hakim, Budianto, Burhan, Basran, Oktaviana, Adhi Agus, Sumantri, Iwan, Zhao, Jian-xin, Aubert, Maxime, Sardi, Ratno, McGahan, David, Saiful, Andi Muhammad, Adhityatama, Shinatria, Kaifu, Yousuke“…Major gaps remain in our knowledge of the early history of Homo sapiens in Wallacea. By 70–60 thousand years ago (ka), modern humans appear to have entered this distinct biogeographical zone between continental Asia and Australia. …”
Publicado 2021
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255por Maggio, Roberto, Fasciani, Irene, Carli, Marco, Petragnano, Francesco, Marampon, Francesco, Rossi, Mario, Scarselli, Marco“…Here, we summarize evidence that supports these conjectures, fostering new ideas about the physiological role played by receptor homo- and hetero-oligomerization in cell biology.…”
Publicado 2021
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256por Moasses Ghafary, Soroush, Soriano-Teruel, Paula M., Lotfollahzadeh, Shima, Sancho, Mónica, Serrano-Candelas, Eva, Karami, Fatemeh, Barigye, Stephen J., Fernández-Pérez, Iván, Gozalbes, Rafael, Nikkhah, Maryam, Orzáez, Mar, Hosseinkhani, Saman“…While there exist molecular inhibitors specific for the various components of inflammasome complexes, no currently reported inhibitors specifically target NLRP3(PYD) homo-oligomerization. In the present study, we describe the identification of QM380 and QM381 as NLRP3(PYD) homo-oligomerization inhibitors after screening small molecules from the MyriaScreen library using a split-luciferase complementation assay. …”
Publicado 2022
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257“…CONCLUSIONS: Direct comparison of the kinomes of Homo sapiens, P. falciparum and P. vivax sheds additional light on the previously documented divergence of many P. falciparum and P. vivax kinases from those of their human host. …”
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258“…The combined interaction of 2,3,6,7-tetrahydro-5H-thiazolo[3,2-a] pyrimidine (ITU) as the organocatalytic nucleophile with YCl(3) as Lewis acid cocatalyst, generating ITU/YCl(3), was employed for homo- and copolymerization of ε-caprolactone (CL) with δ-valerolactone (VL). …”
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259por Zollikofer, Christoph P. E., Bienvenu, Thibault, Beyene, Yonas, Suwa, Gen, Asfaw, Berhane, White, Tim D., Ponce de León, Marcia S.“…Fossils and artifacts from Herto, Ethiopia, include the most complete child and adult crania of early Homo sapiens. The endocranial cavities of the Herto individuals show that by 160,000 y ago, brain size, inferred from endocranial size, was similar to that seen in modern human populations. …”
Publicado 2022
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260“…Together with pelvic and endocranial morphology, reconstructed PGRs indicate the need for increasing maternal energetics during pregnancy over the last 6 million years, reaching a human-like PGR (i.e., more similar to humans than to other extant apes) and ECV in later Homo less than 1 million years ago.…”
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