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2981“…The relative importance of each of the four ASIC1a oligomers was critically dependent on the availability of cysteines in the transmembrane domain for crosslinking, consistent with the presence of ASIC1a homo-oligomers. The expression of ASIC1a monomers, trimeric or tetrameric concatemeric cDNA constructs resulted in functional channels. …”
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2982por Cui, Jinxing, Yao, Mingguang, Yang, Hua, Liu, Ziyang, Ma, Fengxian, Li, Quanjun, Liu, Ran, Zou, Bo, Cui, Tian, Liu, Zhenxian, Sundqvist, Bertil, Liu, Bingbing“…Pressure induced a significant reduction of the band gap of the crystal. The HOMO-LUMO gap of the Sm@C(88) molecule decreases remarkably at 7 GPa as the carbon cage is deformed. …”
Publicado 2015
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2983por Ding, Li Ping, Zhang, Fang Hui, Zhu, Yong Sheng, Lu, Cheng, Kuang, Xiao Yu, Lv, Jian, Shao, Peng“…In addition, no significant structural differences are observed between the neutral and cation charged silicon clusters with n = 20–24, both of them favor prolate structures. The HOMO-LUMO gaps and vertical ionization potential patterns indicate that Si(22) is the most chemical stable cluster, and its dynamical stability is deeply discussed by the vibrational spectra calculations.…”
Publicado 2015
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2984por Chen, Jishi, Liu, Liren, Weng, Linhong, Lin, Yuejian, Liao, Lingwen, Wang, Chengming, Yang, Jinlong, Wu, Zhikun“…All of these clusters are rather robust (anti-reductive and anti-oxidative) owing to their tiara-like structures with large HOMO-LUMO gaps. Finally, the optical and electrochemical evolution with the increase of ring size was investigated, and it is found that both optical and electrochemical gaps have a “turning point” at a size corresponding to n = 8 for [Pd(SR)(2)](n) nanoclusters.…”
Publicado 2015
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2985“…The roles of the long-range and dispersion corrections on their geometrical parameters, thermodynamic functions, kinetics, dipole moments, Highest Occupied Molecular Orbital–Lowest Unoccupied Molecular Orbital (HOMO–LUMO) energy gaps and total hyperpolarizability were investigated. …”
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2986“…Six different ASICs have been identified (ASIC1a, ASIC1b, ASIC2a, ASIC2b, ASIC3, ASIC4) that are activated by a drop in extracellular pH, either as homo- or heteromers. An exception is ASIC4, which is not activated by protons as a homomer and which does not contribute to functional heteromeric ASICs. …”
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2987“…Of the approximately ~2.65 × 10(3) mature microRNAs (miRNAs) so far identified in Homo sapiens, only a surprisingly small but select subset—about 35–40—are highly abundant in the human central nervous system (CNS). …”
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2988por Abbey, Megha, Hakim, Cosima, Anand, Roopsee, Lafera, Juri, Schambach, Axel, Kispert, Andreas, Taft, Manuel H., Kaever, Volkhard, Kotlyarov, Alexey, Gaestel, Matthias, Menon, Manoj B.“…Although biochemical analysis of the mutants demonstrates differences in homo- and/or hetero-polymerization, in GTP-binding and/or GTPase activities, all analyzed mutants were able to rescue the cytokinesis phenotype of Sept7(flox/flox)fibroblasts associated with Cre-mediated deletion of endogenous Sept7. …”
Publicado 2016
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2989“…Most eukaryotic ACCs are 250 kD, multi-domain enzymes and function as homo-dimers and higher oligomers. They contain a unique, 80 kD central region that shares no homology with other proteins. …”
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2990“…ZnO NWs and NRs show homogeneous distribution of the LUMO and HOMO orbitals all over the entire heterostructure. …”
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2991por Oxenoid, Kirill, Dong, Ying, Cao, Chan, Cui, Tanxing, Sancak, Yasemin, Markhard, Andrew L., Grabarek, Zenon, Kong, Liangliang, Liu, Zhijun, Ouyang, Bo, Cong, Yao, Mootha, Vamsi K., Chou, James J.“…Here, we report the structure of the core region of MCU, determined using nuclear magnetic resonance (NMR) and electron microscopy (EM). MCU is a homo-oligomer with the second transmembrane helix forming a hydrophilic pore across the membrane. …”
Publicado 2016
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2992“…We predicted 37112 interactions for 4567 rice proteins, including 1671 predicted self interactions (homo-interactions) and 35441 predicted interactions between different proteins (hetero-interactions). …”
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2993por Foster, Alan C., Farnsworth, Jill, Lind, Genevieve E., Li, Yong-Xin, Yang, Jia-Ying, Dang, Van, Penjwini, Mahmud, Viswanath, Veena, Staubli, Ursula, Kavanaugh, Michael P.“…In this work we show that the SLC1 amino acid transporter family members SLC1A4 (ASCT1) and SLC1A5 (ASCT2) mediate homo- and hetero-exchange of D-serine with physiologically relevant kinetic parameters. …”
Publicado 2016
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2994por Zainabadi, Kayvan“…This complex, likely composed of a homo-oligomer of 160kDa CLAG3, may represent a functional subunit, possibly the pore, of PSAC.…”
Publicado 2016
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2995“…Sequence alignment and homology across species using BLAST analysis revealed 97%, 97%, 99%, 98%, and 80% sequence homology with Bos taurus, Bos indicus, Ovis aries, Capra hircus, and Homo sapiens, respectively.…”
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2996“…These were explored in the context of a plant genome (Oryza sativa, ∼500 Mbp) and a mammalian genome (Homo sapiens, ∼3.1 Gbp). Analysis of simulated and real smRNA-seq data demonstrates that mapper selection impacts differential expression results and interpretation. …”
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2997por Ho, Nhu Thuy, Tien, Huynh Ngoc, Jang, Se-Joeng, Senthilkumar, Velusamy, Park, Yun Chang, Cho, Shinuk, Kim, Yong Soo“…The current work reports the design and fabrication of an IML using a simple solution process. The efficiency of a homo-tandem device with poly(3-hexylthiophene):phenyl-C61-butyric acid methyl ester as an active layer and poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)/poly(ethylenimine) as an IML was initially found to be 3.40%. …”
Publicado 2016
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2998“…The protein product of the Homo sapiens TP53 gene is a transcription factor (p53) that regulates the expression of genes critical for the response to DNA damage and tumor suppression, including genes involved in cell cycle arrest, apoptosis, DNA repair, metabolism, and a number of other tumorigenesis-related pathways. …”
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2999por Li, Wei, Otsuka, Munechika, Kato, Takehito, Wang, Yang, Mori, Takehiko, Michinobu, Tsuyoshi“…This could be due to its more suitable highest occupied molecular orbital (HOMO) level and higher hole mobility.…”
Publicado 2016
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3000“…Evidence of the co-operative aggregation of differently sized nanoparticles (with different cloud points) is shown using transmission electron microscopy; particles with higher cloud points aggregate with those with lower cloud points with homo-aggregates not seen, demonstrating the co-operative behaviour. …”
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