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  1. 3381
    por Manley, David W, Walton, John C
    Publicado 2015
    “…Carboxylic acids were particularly fruitful affording C-centered radicals that alkylated alkenes and took part in tandem addition cyclizations producing chromenopyrroles; decarboxylative homo-dimerizations were also observed. Acceptors initially yielding radical anions included nitroaromatics and aromatic iodides. …”
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    Preparative semiconductor photoredox catalysis: An emerging theme in organic synthesis
  2. 3382
    “…Therefore, to test whether aggregate recognition might be a general phenomenon rather than one involving a specific GPP130 determinant, we induced homo-oligomerization of two unrelated Golgi-targeted constructs using the FKBP strategy. …”
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    Induced oligomerization targets Golgi proteins for degradation in lysosomes
  3. 3383
    “…Here we provide a detailed technological study and evidence of the use of these tools on the butchery and consumption of fauna, probably by early Homo erectus sensu lato.…”
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    The Origin of The Acheulean: The 1.7 Million-Year-Old Site of FLK West, Olduvai Gorge (Tanzania)
  4. 3384
    “…Theoretically, twelve new analogs of 1 were prepared and their comparative reactivity (HOMO–LUMO energy) and biodecomposition (on the basis of polarizability) is discussed. …”
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    Unexpected formation of N′-phenyl-thiophosphorohydrazidic acid O,S-dimethyl ester from acephate: chemical, biotechnical and computational study
  5. 3385
    “…Finally the momentum maps down to HOMO-11 will be analysed and real space orbitals reconstructed.…”
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    Orbital tomography: Molecular band maps, momentum maps and the imaging of real space orbitals of adsorbed molecules
  6. 3386
    “…We observed the same distributions of GIs among non-ribosomal HI, ribosomal HI and HS genes in three other species: Schizosaccharomyces pombe, Drosophila melanogaster and Homo sapiens. One potentially interesting exception was the lack of significant differences in the degree of GIs between non-ribosomal HI and HS genes in Schizosaccharomyces pombe. …”
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    Dominance from the perspective of gene–gene and gene–chemical interactions
  7. 3387
    “…This caspase cleavage site is conserved in various species from zebrafish to Homo sapiens. The 80kDa fragment of iASPP translocates from the cytoplasm to the nucleus via the RaDAR nuclear import pathway, independent of p53. …”
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    Caspase cleavage of iASPP potentiates its ability to inhibit p53 and NF-κB
  8. 3388
    “…In a quantum calculation study, the energy difference between HOMO and LUMO (gap) implied the high interaction of the most active molecule in the active site of the protein. …”
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    Alignment independent 3D-QSAR, quantum calculations and molecular docking of Mer specific tyrosine kinase inhibitors as anticancer drugs
  9. 3389
    “…Asymmetric Ir-catalyzed C–C coupling of primary alcohols with allyl-acetates, as described by Krische, to form chiral secondary homo-allylic alcohols were performed in parallel as a means to optimize the ee values thereof. …”
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    Application of a high-throughput enantiomeric excess optical assay involving a dynamic covalent assembly: parallel asymmetric allylation and ee sensing of homoallylic alcohols
  10. 3390
    “…The barrel architecture of these proteins is formed by either homo-/hetero-dimerization or duplication and fusion of ferredoxin-like domains. …”
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    Evolutionary relationships between heme-binding ferredoxin α + β barrels
  11. 3391
    “…Risk factors for HIV acquisition were unprotected sexual intercourse (homo/bisexual in 39.8% and heterosexual in 60.2%). …”
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    Screening for Neurocognitive Impairment in HIV-Infected Individuals at First Contact after HIV Diagnosis: The Experience of a Large Clinical Center in Northern Italy
  12. 3392
    “…But in spite of this effort, devices fabricated from them still use homo-epitaxy only. Here we present an epitaxial technique based on the epitaxial lateral overgrowth of micrometer scale GaAs crystals on a thin SiO(2) layer from nanoscale Si seeds. …”
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    High current density GaAs/Si rectifying heterojunction by defect free Epitaxial Lateral overgrowth on Tunnel Oxide from nano-seed
  13. 3393
    “…In the canonical glucose-derived serine synthesis pathway, Homo sapiens phosphoglycerate dehydrogenase (PHGDH) catalyzes the first, rate-limiting step. …”
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    A PHGDH inhibitor reveals coordination of serine synthesis and 1-carbon unit fate
  14. 3394
    “…This same polymorphism has also been shown to generate weaker sEH homo-dimers. Taken together, these observations suggest that dimerization may mask the sEH PTS and prevent peroxisome translocation. …”
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    Disrupting Dimerization Translocates Soluble Epoxide Hydrolase to Peroxisomes
  15. 3395
    “…Disruption of this domain in TPC1 either by deletion or point mutations impeded the dimerization and cation transport. The homo-dimerization of the CTH was analyzed in silico using coarse-grained molecular dynamics (MD) simulations for the study of aggregation, followed by atomistic MD simulations. …”
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    The function of the two-pore channel TPC1 depends on dimerization of its carboxy-terminal helix
  16. 3396
    por Shen, Zu T., Sigalov, Alexander B.
    Publicado 2016
    “…Recently, based on our model of immune signaling, the Signaling Chain HOmoOLigomerization (SCHOOL) model, we suggested specific molecular mechanisms used by different viruses such as severe acute respiratory syndrome coronavirus (SARS-CoV) to modulate the host immune response mediated by members of the family of multichain immune recognition receptors (MIRRs). …”
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    SARS Coronavirus Fusion Peptide-Derived Sequence Suppresses Collagen-Induced Arthritis in DBA/1J Mice
  17. 3397
    “…We found that TATDN1 (Homo sapiens TatD DNase domain containing 1, TATDN1), one of LncRNAs, was highly expressed in 95D cells and NSCLC tumor tissues compared to 95C cells. …”
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    The role and potential mechanisms of LncRNA-TATDN1 on metastasis and invasion of non-small cell lung cancer
  18. 3398
    por Honda, Tomoyuki, Tomonaga, Keizo
    Publicado 2016
    “…We have recently demonstrated that all Homo sapiens EBLNs are expressed in at least one tissue. …”
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    Endogenous non-retroviral RNA virus elements evidence a novel type of antiviral immunity
  19. 3399
    por Mei, Suyu, Zhang, Kun
    Publicado 2016
    “…In this study we propose a noise-tolerant homolog knowledge transfer method to reconstruct functional protein-protein interactions (PPI) networks between Epstein-Barr virus and Homo sapiens. The training set is augmented via homolog instances and the homolog noise is counteracted by support vector machine (SVM). …”
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    Computational discovery of Epstein-Barr virus targeted human genes and signalling pathways
  20. 3400
    “…Serum concentration of adropin was significantly lower in patients than that of the healthy subjects (P < 0.0001), especially those with Enho mutations. In vivo, homo- and heterozygous carriers of the null adropin allele exhibited MPO-ANCA associated pulmonary alveolar hemorrhage as compared to wild-type mice. …”
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    Enho Mutations Causing Low Adropin: A Possible Pathomechanism of MPO-ANCA Associated Lung Injury
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