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  1. 3421
    “…For instance, we found gain and loss of important phosphorylation sites in the Homo sapiens FOXP2 IDR regions, with possible implication for the evolution of human speech.…”
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    FOXP in Tetrapoda: Intrinsically Disordered Regions, Short Linear Motifs and their evolutionary significance
  2. 3422
    “…Detailed theoretical analysis of a disilylated Eu(II) complex suggests that its singly occupied molecular orbitals (SOMOs) are very close in energy to the ligand silicon lone pairs (HOMO), and SQUID magnetometry measurements of the complex showed a deviation from the expected behavior for a free Eu(II) ion, which might be due to a ligand–metal interaction.…”
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    Using Functionalized Silyl Ligands To Suppress Solvent Coordination to Silyl Lanthanide(II) Complexes
  3. 3423
    “…Cytokine and growth-factor ligands typically signal through homo- or hetero-dimeric cell surface receptors via Janus Kinase (JAK/TYK), or Receptor Tyrosine Kinase (RTK)-mediated trans-phosphorylation. …”
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    Synthekines are surrogate cytokine and growth factor agonists that compel signaling through non-natural receptor dimers
  4. 3424
    “…This was also observed for diabetes duration but only reached significance when both (CTG)(5) homo- and heterozygous patients were included. CN-1 activity negatively correlated with time on hemodialysis and was lower in (CTG)(5) homozygous patients. …”
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    The CNDP1 (CTG)(5) Polymorphism Is Associated with Biopsy-Proven Diabetic Nephropathy, Time on Hemodialysis, and Diabetes Duration
  5. 3425
    “…The major types of dominant mutation were significantly associated with the different types of molecular interactions, such as protein-DNA, homo-oligomerization, or intramolecular domain-domain interactions, affected by mutations. …”
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    Decoding disease-causing mechanisms of missense mutations from supramolecular structures
  6. 3426
    por Bentley, Stephen J., Boshoff, Aileen
    Publicado 2017
    “…The assembly and annotation of the G. m. morsitans genome provided a platform to identify and characterize the Hsp70s and J-proteins, and carry out an evolutionary comparison to its well-studied eukaryotic counterparts, Drosophila melanogaster and Homo sapiens, as well as Stomoxys calcitrans, a comparator species. …”
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    Hsp70/J-protein machinery from Glossina morsitans morsitans, vector of African trypanosomiasis
  7. 3427
    “…By interacting with other bZIP transcription factors, sMAFs can form homo- and heterodimers governing either repressive or activating transcriptional functions. …”
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    miR-128 Is Implicated in Stress Responses by Targeting MAFG in Skeletal Muscle Cells
  8. 3428
    por Moosavi, Azam, Ardekani, Ali M.
    Publicado 2017
    “…RESULTS: Among 227 β-thalassemia minor individuals studied, α-globin gene deletions were found in 43 cases: 37 heterozygote −α3.7 (16.3%), 5 homo −α3.7 (2.2%) and 1 --MED (0.44%). Also, the co-inheritance of α-globin gene deletion and triplication was not found in the studied individuals. …”
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    The Frequency and Importance of Common α-globin Gene Deletions Among β-Thalassemia Carriers in an Iranian Population
  9. 3429
    “…In addition, 98.68% of SNPs were found to be homo-variants, suggesting that the two species have long evolved from different niches. …”
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    Comparative analysis of genome sequences of the conifer tree pathogen, Heterobasidion annosum s.s.
  10. 3430
    “…This robust system can proceed without any additives, and offers a versatile and green way to produce well-defined homo and block copolymers.…”
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    A well-defined, versatile photoinitiator (salen)Co–CO(2)CH(3) for visible light-initiated living/controlled radical polymerization
  11. 3431
    “…We explored whether LV3-PIEZO1-homo-3201 could act as Piezo1-shRNA, which could then be an inhibitor of Piezo1. …”
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    The Function of the Novel Mechanical Activated Ion Channel Piezo1 in the Human Osteosarcoma Cells
  12. 3432
    “…The molecular mechanisms that support RNAi in pest species are reviewed in detail, drawing on literature from a range of species including Drosophila melanogaster Meigen and Homo sapiens L. The underlying genes that enable RNAi are generally conserved across taxa, although variance exists in both their form and function. …”
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    Implementing the sterile insect technique with RNA interference – a review
  13. 3433
    “…The HKRD is a dimerization domain for PHYB homo and heterodimerization. A D1040V mutation, which disrupts the dimerization of HKRD and the interaction between C-terminal module and PIF3, abrogates PHYB nuclear accumulation, photobody biogenesis, and PIF3 degradation. …”
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    Mechanism of early light signaling by the carboxy-terminal output module of Arabidopsis phytochrome B
  14. 3434
    “…The original data source, the reformatting procedure and the biological characteristics of the samples are described in an accompanying documentation file manually edited by data curators. 10 model organisms are currently represented: Homo sapiens, Mus musculus, Danio rerio, Drosophila melanogaster, Apis mellifera, Caenorhabditis elegans, Arabidopsis thaliana, Zea mays, Saccharomyces cerevisiae and Schizosaccharomyces pombe. …”
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    MGA repository: a curated data resource for ChIP-seq and other genome annotated data
  15. 3435
    “…Our analyses reveal that this mandible is more closely related to the ancient specimens from the African and Eurasian Early and Middle Pleistocene, particularly due to the presence of primitive features of the Homo clade. In contrast, the external morphology of the molars is clearly similar to that of Neandertals. …”
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    A reassessment of the Montmaurin-La Niche mandible (Haute Garonne, France) in the context of European Pleistocene human evolution
  16. 3436
    “…Danio rerio are amenable to in vivo imaging, high-throughput drug screening, mutagenesis, and transgenesis, and they share histological and genetic similarities with Homo sapiens. The significance of zebrafish in the field of precision oncology is rapidly emerging. …”
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    Fishing for cures: The alLURE of using zebrafish to develop precision oncology therapies
  17. 3437
    “…Nucleophosmin (NPM1) is a multifunctional phosphoprotein which plays important roles in diverse biological processes. NPM1 can form homo- or hetero-oligomers through its N-terminal region, and bind DNA and RNA through its C-terminal region. …”
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    Analysis of the oligomeric states of nucleophosmin using size exclusion chromatography
  18. 3438
    “…The molecular frontier orbitals analysis indicates that Ti(12)C(68) cage has a narrow HOMO-LUMO gap with metal-like property. It would be expected to enrich the species of hollow metal carbide clusters.…”
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    Ti(12)C(68): A stable T(h)-symmetry hollow cage
  19. 3439
    “…Because both TgCPB and TgCPL play a role in T. gondii invasion, we evaluated the efficacy of the potent, irreversible vinyl sulfone inhibitor, K11777 (N-methyl-piperazine-Phe-homoPhe-vinylsulfone-phenyl). The inhibitor’s toxicity and pharmacokinetic profile have been well-studied because of its in vitro and in vivo activity against a number of parasites. …”
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    Two key cathepsins, TgCPB and TgCPL, are targeted by the vinyl sulfone inhibitor K11777 in in vitro and in vivo models of toxoplasmosis
  20. 3440
    “…Protein–protein interaction assays showed that sugarcane FBH1 (ScFBH1), ScFBH2, and ScFBH3 form homo- and heterodimers in the nucleus. Gene expression analysis revealed that ScFBHs and ScACS2 transcripts are more abundant in maturing internodes during afternoon and night. …”
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    The FBH family of bHLH transcription factors controls ACC synthase expression in sugarcane
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