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3781“…Including three comparative species in the process of predicting TF roles in Saccharomyces cerevisiae and Homo sapiens increases the number of significant predictions by 75 and 200%, respectively. …”
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3782por Fu, Sheng, Tong, Xiaohang, Cai, Chenguang, Zhao, Ying, Wu, Yang, Li, Yuanyuan, Xu, Junjie, Zhang, Xuejun C., Xu, Long, Chen, Wei, Rao, Zihe“…PA binds a receptor on the surface of the target cell and further assembles into a homo-heptameric pore through which EF and LF translocate into the cytosol. …”
Publicado 2010
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3783por Pham, Nancy, Fazio, Vincent, Cucullo, Luca, Teng, Qingshan, Biberthaler, Peter, Bazarian, Jeffrey J., Janigro, Damir“…We also measured the levels of S100B homo- and heterodimers in serum quantitatively after blood-brain barrier disruption. …”
Publicado 2010
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3784por Fustiñana, Maria Sol, Ariel, Pablo, Federman, Noel, Freudenthal, Ramiro, Romano, Arturo“…RESULTS: Here we partially cloned and sequenced the beta-amyloid precursor protein like gene homologue in the crab Chasmagnathus (cappl), showing a 37% of identity with the fruit fly Drosophila melanogaster homologue and 23% with Homo sapiens but with much higher degree of sequence similarity in certain regions. …”
Publicado 2010
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3785KIF21A mutations in two Chinese families with congenital fibrosis of the extraocular muscles (CFEOM)por Yang, Xian, Yamada, Koki, Katz, Bradley, Guan, Hongzai, Wang, Lifei, Andrews, Caroline, Zhao, Guiqiu, Engle, Elizabeth C., Chen, Haoyu, Tong, Zongzhong, Kong, Jie, Hu, Cong, Kong, Qinglan, Fan, Guiyun, Wang, Ze, Ning, Meizhen, Zhang, Shaoyan, Xu, Jinling, Zhang, Kang“…The purpose of this study was to determine if previously described Homo sapiens kinesin family member 21A (KIF21A) mutations were responsible for CFEOM in these two Chinese pedigrees. …”
Publicado 2010
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3786“…We show an average improvement of 4.6 times the F(1 )score over Resnik, the next best method, on our Saccharomyces cerevisiae PPI dataset and 2 times on our Homo sapiens PPI dataset using cellular component, biological process and molecular function GO annotations.…”
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3787por Sato, Aya, Yokotani, Sonoko, Tadokoro, Takashi, Tanaka, Shun-ichi, Angkawidjaja, Clement, Koga, Yuichi, Takano, Kazufumi, Kanaya, Shigenori“…The overall structure of SIB1–CutA1 is similar to those of CutA1 from Homo sapiens, Escherichia coli, Pyrococcus horikoshii, Thermus thermophilus, Termotoga maritima, Oryza sativa and Rattus norvergicus. …”
Publicado 2011
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3788“…Additional distal tibiae from the Plio-Pleistocene show variation in tibial arch angles, including two early Homo tibiae that also have slightly posteriorly directed tibial arch angles. …”
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3789por Pyo, Chul-Woo, Guethlein, Lisbeth A., Vu, Quyen, Wang, Ruihan, Abi-Rached, Laurent, Norman, Paul J., Marsh, Steven G. E., Miller, Jeffrey S., Parham, Peter, Geraghty, Daniel E.“…In contrast, the telomeric motifs that distinguish A and B haplotypes emerged more recently, ∼1.7 million years ago, before the emergence of Homo sapiens. Thus the centromeric and telomeric motifs that typify A and B haplotypes have likely been present throughout human evolution. …”
Publicado 2010
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3790por Cer, Regina Z., Bruce, Kevin H., Mudunuri, Uma S., Yi, Ming, Volfovsky, Natalia, Luke, Brian T., Bacolla, Albino, Collins, Jack R., Stephens, Robert M.“…The database also contains motifs predicted to form static DNA bends, short tandem repeats and homo(purine•pyrimidine) tracts that have been associated with disease. …”
Publicado 2011
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3791por Gur, Amit, Semel, Yaniv, Osorio, Sonia, Friedmann, Michael, Seekh, Saleh, Ghareeb, Bilal, Mohammad, Ayed, Pleban, Tzili, Gera, Gabi, Fernie, Alisdair R., Zamir, Dani“…To further examine this unusual case, we evaluated the metabolic profiles of fruits from both the homo- and heterozygous lines for IL8-3 and compared these to those obtained from the fruit of their equivalent genotypes in the root effect population. …”
Publicado 2010
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3792“…Nevertheless, the extremely long thin Tp and complex junctional structures that they form and the release of vesicles (or exosomes) indicate the participation of TCs in long-distance homo- or heterocellular communication. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00441-010-1095-0) contains supplementary material, which is available to authorized users.…”
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3793“…METHODOLOGY/PRINCIPAL FINDINGS: We implemented a computational approach to predict interactions between Dengue virus (DENV) and both of its hosts, Homo sapiens and the insect vector Aedes aegypti. …”
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3794“…Here we perform a genomic study of RNA secondary structures around splice sites in humans (Homo sapiens), mice (Mus musculus), fruit flies (Drosophila melanogaster), and nematodes (Caenorhabditis elegans) to further investigate this phenomenon. …”
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3795por Santorelli, Claire J., Schaffner, Colleen M., Campbell, Christina J., Notman, Hugh, Pavelka, Mary S., Weghorst, Jennifer A., Aureli, Filippo“…Spider monkeys possess a relatively rare social system with a high degree of fission-fusion dynamics, also typical of chimpanzees (Pan troglodytes) and humans (Homo sapiens). From the initial 62 behaviors surveyed 65% failed to meet the necessary criteria for traditions. …”
Publicado 2011
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3796por Seleem, Hussein S, El-Inany, Gaber A, El-Shetary, Bashir A, Mousa, Marwa A, Hanafy, Fatin I“…As continuation of our interest, the present study is planned to check the ligational behavior of an isatinic quinolyl hydrazone. RESULTS: New homo- and heteroleptic copper(II)- complexes were obtained from the reaction of an isatinic quinolyl hydrazone (HL) with several copper(II)- salts viz. …”
Publicado 2011
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3797“…This method was applied to the IL-2Rβ and IL-2Rγ TMD sequences of Homo sapiens, Rattus norvegicus, Mus musculus and Bos taurus. …”
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3798“…Dact proteins also formed complexes with themselves and with each other; their conserved N-terminal leucine-zipper domains, which have no known binding partners, were necessary and sufficient for this interaction, suggesting that it reflects leucine-zipper-mediated homo- and hetero-dimerization. We also found weaker, though conserved, interactions of all three Dact paralogs with the catenin superfamily member p120ctn. …”
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3799por Pattanayek, Rekha, Williams, Dewight R., Rossi, Gian, Weigand, Steven, Mori, Tetsuya, Johnson, Carl H., Stewart, Phoebe L., Egli, Martin“…The circadian clock in the cyanobacterium Synechococcus elongatus is composed of a post-translational oscillator (PTO) that can be reconstituted in vitro from three different proteins in the presence of ATP and a transcription-translation feedback loop (TTFL). The homo-hexameric KaiC kinase, phosphatase and ATPase alternates between hypo- and hyper-phosphorylated states over the 24-h cycle, with KaiA enhancing phosphorylation, and KaiB antagonizing KaiA and promoting KaiC subunit exchange. …”
Publicado 2011
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3800por Popescu, Laurentiu M., Gherghiceanu, Mihaela, Suciu, Laura C., Manole, Catalin G., Hinescu, Mihail E.“…Tp ramify dichotomously, making a 3-dimensional network with complex homo- and heterocellular junctions. Confocal microscopy reveals that TCs are c-kit- and CD34-positive. …”
Publicado 2011
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