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3941por Zhen, Shoumin, Deng, Xiong, Wang, Jian, Zhu, Gengrui, Cao, Hui, Yuan, Linlin, Yan, Yueming“…Among the 262 succinylated proteins, 170 of them were found to have homologous proteins in Oryza sativa L., Escherichia coli, Sacchayromyces cerevisiae, or Homo sapiens. Motif-X analysis of the acetylated and succinylated sites identified two new acetylated motifs (K---K and K-I-K) and twelve significantly enriched succinylated motifs for the first time, which could serve as possible binding loci for future studies in plants. …”
Publicado 2016
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3942por Kurkewich, Jeffrey L., Klopfenstein, Nathan, Hallas, William M., Wood, Christian, Sattler, Rachel A., Das, Chhaya, Tucker, Haley, Dahl, Richard, Cowden Dahl, Karen D.“…Arid3a and Arid3b are closely related and share a unique REKLES domain that mediates their homo- and hetero-multimerization. Arid3a was originally isolated as a B cell transcription factor binding to the AT rich matrix attachment regions (MARS) of the immunoglobulin heavy chain intronic enhancer. …”
Publicado 2016
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3943“…RESULTS: Our basic scheme compressed the Homo sapiens genome (with an original size of 3,080,436,051 bytes) to 15,460,478 bytes. …”
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3944“…Predictive models were employed using SVM for developing pipeline-1 (classification) and pipeline-2 (regression) using 2090 and 4139 experimentally verified sgRNAs respectively from Homo sapiens, Mus musculus, Danio rerio and Xenopus tropicalis. …”
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3945por Sztatelman, Olga, Łabuz, Justyna, Hermanowicz, Paweł, Banaś, Agnieszka Katarzyna, Bażant, Aneta, Zgłobicki, Piotr, Aggarwal, Chhavi, Nadzieja, Marcin, Krzeszowiec, Weronika, Strzałka, Wojciech, Gabryś, Halina“…The formation of phototropin homo- and heterocomplexes is the most plausible explanation of the observed phenomena. …”
Publicado 2016
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3946por Vámosi, György, Mücke, Norbert, Müller, Gabriele, Krieger, Jan Wolfgang, Curth, Ute, Langowski, Jörg, Tóth, Katalin“…Fluorescence anisotropy decreased, indicating homoFRET between the subunits. Fluorescence lifetime decreased only slightly (4%) indicating insignificant quenching by FRET to subunits in non-emitting states. …”
Publicado 2016
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3947“…In rice, eIF3e interacted with eIF3 subunits b, d, e, f, h, and k, and with eIF6, forming homo- and heterodimers to initiate translation. Furthermore, OseIF3e was shown by yeast two-hybrid assay to specifically bind to inhibitors of cyclin-dependent kinases 1, 5, and 6. …”
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3948“…Two ARB2 domain molecules form a compact homo-dimer via the arm elements, and assemble as an inverse “V” shape. …”
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3949por Dietzen, Matthias, Kalinina, Olga V., Taškova, Katerina, Kneissl, Benny, Hildebrandt, Anna‐Katharina, Jaenicke, Elmar, Decker, Heinz, Lengauer, Thomas, Hildebrandt, Andreas“…We compiled a diverse benchmark set of 308 homo and heteromeric complexes containing 6 to 60 monomers. …”
Publicado 2015
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3950por Wu, Chenping, Soomro, Abdul Majid, Sun, Feipeng, Wang, Huachun, Huang, Youyang, Wu, Jiejun, Liu, Chuan, Yang, Xiaodong, Gao, Na, Chen, Xiaohong, Kang, Junyong, Cai, Duanjun“…By HVPE method, overgrowth of thick GaN wafer over 200 μm has been achieved free of residual strain, which could provide high quality homo-epitaxial substrate.…”
Publicado 2016
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3951por Borroto-Escuela, Dasiel O., Wydra, Karolina, Pintsuk, Julia, Narvaez, Manuel, Corrales, Fidel, Zaniewska, Magdalena, Agnati, Luigi F., Franco, Rafael, Tanganelli, Sergio, Ferraro, Luca, Filip, Malgorzata, Fuxe, Kjell“…Our hypothesis is that allosteric receptor-receptor interactions in homo- and heteroreceptor complexes may form the molecular basis of learning and memory. …”
Publicado 2016
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3952“…The interactions of micro-organisms cohabitating with Homo sapiens spans millennia, with microbial communities living in a symbiotic relationship with the host. …”
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3953por Hejazi, Safiyah A., Osman, Osman I., Alyoubi, Abdulrahman O., Aziz, Saadullah G., Hilal, Rifaat H.“…The geometrical structures, dipole moments, HOMO-LUMO energy gaps, total hyperpolarizability, kinetics and thermodynamics functions were monitored against the effects of the corrections imposed on these functionals. …”
Publicado 2016
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3954por Wei, Yunan, Zhou, Hao, Wang, Anqi, Sun, Lipei, Wang, Mingshu, Jia, Renyong, Zhu, Dekang, Liu, Mafeng, Yang, Qiao, Wu, Ying, Sun, Kunfeng, Chen, Xiaoyue, Cheng, Anchun, Chen, Shun“…The protein sequence has 89.25% sequence identity with Anas platyrhynchos TRIM25, 78.57% with Gallus gallus TRIM25, and 46.92% with Homo sapiens TRIM25. TRIM25 is expressed in all gosling and adult goose tissues examined. …”
Publicado 2016
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3955“…The results indicate that the most significant transition in efficiency likely took place with the introduction of small foliate biface, Levallois and prismatic blade knapping, all introduced in the Middle Stone Age / Middle Palaeolithic among early Homo sapiens and Neanderthals. This suggests that no difference in raw material efficiency existed between these species. …”
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3956por Al-Hilaly, Youssra K., Biasetti, Luca, Blakeman, Ben J. F., Pollack, Saskia J., Zibaee, Shahin, Abdul-Sada, Alaa, Thorpe, Julian R., Xue, Wei-Feng, Serpell, Louise C.“…A covalently cross-linked dimer isolated by SDS-PAGE and mass analysis showed that dityrosine dimer was formed via the coupling of Y39-Y39 to give a homo dimer peptide that may play a key role in formation of oligomeric and seeds for fibril formation. …”
Publicado 2016
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3957por Mathieu, Christoph, Macêdo, Juan P., Hürlimann, Daniel, Wirdnam, Corina, Haindrich, Alexander C., Suter Grotemeyer, Marianne, González-Salgado, Amaia, Schmidt, Remo S., Inbar, Ehud, Mäser, Pascal, Bütikofer, Peter, Zilberstein, Dan, Rentsch, Doris“…L-arginine transport was reduced by a 10-times excess of L-arginine, homo-arginine, canavanine or arginine-β-naphthylamide, while lysine was inhibitory only at 100-times excess, and histidine or ornithine did not reduce arginine uptake rates significantly. …”
Publicado 2017
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3958por Backes, Christina, Kehl, Tim, Stöckel, Daniel, Fehlmann, Tobias, Schneider, Lara, Meese, Eckart, Lenhof, Hans-Peter, Keller, Andreas“…The database contains a large number of miRNAs (2595 human miRNAs), different miRNA target sets (14 773 experimentally validated target genes as well as 19 281 predicted targets genes) and a broad selection of functional biochemical categories (KEGG-, WikiPathways-, BioCarta-, SMPDB-, PID-, Reactome pathways, functional categories from gene ontology (GO), protein families from Pfam and chromosomal locations totaling 12 875 categories). In addition to Homo sapiens, also Mus musculus data are stored and can be compared to human target pathways.…”
Publicado 2017
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3959“…Furthermore, we applied interference peptides and MALDI-TOF mass spectrometry to confirm APJ homo-dimer and explore the dimer-interfaces. Peptides corresponding to transmembrane domain (TMD)1, 2, 3, and 4, but not TMD5, 6, and 7, disrupted APJ dimerization. …”
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3960por Hewitt, Stephen Nakazawa, Dranow, David M., Horst, Benjamin G., Abendroth, Jan A., Forte, Barbara, Hallyburton, Irene, Jansen, Chimed, Baragaña, Beatriz, Choi, Ryan, Rivas, Kasey L., Hulverson, Matthew A., Dumais, Mitchell, Edwards, Thomas E., Lorimer, Donald D., Fairlamb, Alan H., Gray, David W., Read, Kevin D., Lehane, Adele M., Kirk, Kiaran, Myler, Peter J., Wernimont, Amy, Walpole, Chris, Stacy, Robin, Barrett, Lynn K., Gilbert, Ian H., Van Voorhis, Wesley C.“…In this paper, approximately 40,000 compounds were screened to identify compounds that selectively inhibit PfProRS enzyme activity versus Homo sapiens (Hs) ProRS. X-ray crystallography structures were solved for apo, as well as substrate- and inhibitor-bound forms of PfProRS. …”
Publicado 2016
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