“…A paradigm shift in neuroscience was the discovery that new neurons are constantly produced in the adult mammalian brain of several species, including Homo sapiens. These new-born cells are formed in some main neurogenic niches, including the subventricular zone (SVZ) at the margin of the lateral ventricle and subgranular zone (SGZ) in the hippocampal dentate gyrus (DG). …”
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“…The aryl‐cobinamides were obtained as pairs of organometallic coordination isomers, the stereo‐structure of which was unambiguously assigned based on homo‐ and heteronuclear NMR spectra. The availability of isomers with axial attachment of the aryl group, either at the ‘beta’ or at the ‘alpha’ face of the cobalt‐center allowed for an unprecedented comparison of the organometallic reactivity of such pairs. …”
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“…This synthesis is also transferable to the already known homo‐dipnictogen complexes [{CpMo(CO)(2)}(2)(μ,η(2):η(2)‐E(2))] (E=P, As, Sb, Bi) resulting in higher yields comparable to those in the literature reported procedures and allows the introduction of the bulkier and better soluble Cp′ (Cp′=tert butylcyclopentadienyl) ligand.…”
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“…However, this approach ignores that NRs function as homo- as well as heterodimers and that the LBD harbors the main dimerization interface. …”
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“…Alkaline phosphatase (ALP), a homo‐dimeric enzyme has been widely used in various bioassays as disease markers and enzyme probes. …”
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“…Among five reactive functional groups in epi-CD, two stable complexes of the hydroxyl group (X-epi-CD1) at C(17) and of the quinoline ring (X-epi-CD2) at N(16) with pnictide family analytes [X = substituted phosphine (PX), i.e., F, Br, Cl, CF(3), CN, HO, NO(2), and CH(3), and pnictide family analytes, i.e., PBr(3), BiI(3), SbI(3), and AsI(3)] were predicted with intermolecular interaction energies, charge transfer (Q(Mulliken) and Q(NBO)), and band gap energies of HOMO–LUMO (Eg) at the B3LYP/6-31G(d,p) level of density functional theory. …”
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“…ER tubules regulate lysosome size and axonal translocation by promoting lysosome homo-fission. ER tubule – lysosome contacts often occur at a somatic pre-axonal region, where the kinesin-1-binding ER-protein P180 binds microtubules to promote kinesin-1-powered lysosome fission and subsequent axonal translocation. …”
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“…This paper contributes to the field of Neuro-management by introducing the concept of Homo Relationalis. In this respect, we suggest that leadership is not just a socially constructed element but also a social brain constructed phenomenon that requires an understanding of the human brain as a social organ. …”
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“…Two heteroleptic Ni(II) complexes combined the redox-active catecholate and 2,2′- bipyridine ligand platforms were synthesized to observe a photoinduced intramolecular ligand-to-ligand charge transfer (LL’CT, HOMO(catecholate) → LUMO(α-diimine)). A molecular design of compound [Ni(II)(3,6-Cat)(bipy)]∙CH(3)CN (1) on the base of bulky 3,6-di-tert-butyl-o-benzoquinone (3,6-DTBQ) was an annelation of the ligand with an electron donor glycol fragment, producing derivative [Ni(II)(3,6-Cat(gly))(bipy)]∙CH(2)Cl(2) (2), in order to influence the energy of LL’CT transition. …”
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“…Fraxetin shows significant interactions with STAT3 Src Homology 2 (SH2) domain residues, thereby preventing its homo-dimer formation, which then blocks the activation of downstream signal pathways. …”
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“…Quantum-chemical calculations of the parent tromancenium salt indicate that metal–ligand bonding is distinctly weaker for the cycloheptatrienyl ligand in comparison to that of the cyclopentadienyl ligand. Both the HOMO and the LUMO are metal and cycloheptatrienyl-ligand centered, indicating that chemical reactions will occur either metal-based or at the seven-membered ring, but not on the cyclopentadienyl ligand.…”
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“…The best antioxidant quercetin had the highest value of HOMO energy, a planar structure and optimal electron orbital delocalization on all the phenolic rings due to the C2=C3 double bond in the C ring (absent in catechin and naringenin).…”
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“…Despite similarity in sequence and structure, evidence suggests different biological roles in normal and pathological conditions for each isoform. We compared Homo sapiens and Mus musculus VDAC genes and their regulatory elements. …”
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“…On the other hand, three C2H2 proteins containing the structured domain DUF3669 at the N-terminus demonstrated homo- and heterodimerization activity.…”
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“…The cochlea of P. robustus is distinctive and relatively invariant, whereas cochlear shape in A. africanus is more variable, resembles that of early Homo, and shows a degree of morphological polymorphism comparable to that evinced by modern species. …”
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“…HSPB1 itself was also extracted during disaggregation, and its homo-oligomerization ability was not required. Therefore, we propose that a human sHSP is an integral part of the chaperone network for protein disaggregation.…”
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“…We evaluated three newly synthesized B-lactam hybrid homo-aza-steroidal alkylators (ASA-A, ASA-B and ASA-C) for their PARP1/2 inhibition activity and their DNA damaging effect against human ovarian carcinoma cells. …”
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“…Both enzymes are the so-called form II Rubiscos, but the first is exclusively a homodimer, while the second one forms homo-hexamers. Obtained models show no differences in amino acids crucial for Rubisco activity. …”
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“…Here, we have postulated that Iminodibenzyl, by inhibiting D5D activity, could shift the di-homo-gamma-linolenic acid (DGLA) peroxidation from arachidonic acid to 8-HOA in high COX-2 microenvironment of 4T1 and MDA-MB-231 breast cancer cells. …”
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“…The crystal structure of C. neoformans GARs revealed differences in the glycine- and ATP-binding sites compared with the Homo sapiens enzyme, while the crystal structure of AIRs shows high structural similarity compared with its H. sapiens ortholog as a monomer but differences as a dimer. …”
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