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  1. 4341
    “…Streptavidin (SA) is a homo‐tetrameric protein derived from Streptomyces avidinii, which can bind four biotin molecules with an extremely high affinity at a Kd value of 10(‐15) M. …”
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    A novel multimeric sCD19‐streptavidin fusion protein for functional detection and selective expansion of CD19‐targeted CAR‐T cells
  2. 4342
    por Sonia, Chiging, Devi, Th.Gomti, Karlo, T.
    Publicado 2022
    “…The molecular parameters, such as first-order hyperpolarizability, HOMO-LUMO energy gap, global electrophilicity index, dipole moment, chemical potential, hardness, ionization energy and electron affinity are determined from the calculation. …”
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    DFT study on the structural and chemical properties of Janus kinase inhibitor drug Baricitinib
  3. 4343
    “…This fundamental feature of homo sapiens has been one of the most powerful forces sculpting the advent of modern civilizations. …”
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    Sleep loss leads to the withdrawal of human helping across individuals, groups, and large-scale societies
  4. 4344
    “…This fact is shown to force a change of the HOMO wavefunction favoring that the long axis becomes the Mn(3+)−F(2) (−) direction, not far from crystal b axis, after the subsequent relaxation process. …”
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    Pressure Effects on 3d(n) (n=4, 9) Insulating Compounds: Long Axis Switch in Na(3)MnF(6) not Due to the Jahn‐Teller Effect
  5. 4345
    “…The optical band gap of quantum dots and HOMO/LUMO band structure of functionalized polyurethanes were measured using UV-vis and cyclic voltammetry, and thereby, constructing the overall energy diagrams for a possible combination of materials. …”
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    Functionalized polyurethane composite gel electrolyte with cosensitized photoanode for higher solar cell efficiency using a passivation layer
  6. 4346
    “…Using the Grubbs catalyst, the subsequent olefin metathesis reaction of the mixture gave covalently linked porphyrin dimers through the allyloxy side chains, enabling the isolation of the stable hetero- (ReD′) and homo-dimers (ReD′Re) with gel permeation chromatography. …”
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    Photocatalytic CO(2) reduction sensitized by a special-pair mimic porphyrin connected with a rhenium(i) tricarbonyl complex
  7. 4347
    “…Finally, the difference between the energy of the lowest unoccupied molecular orbital (LUMO) and that of the highest occupied molecular orbital (HOMO) measured on C(60) is about 3.75 eV, a value remarkably higher than those found in fullerene films stabilized directly on metal surfaces. …”
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    Self-assembly of C(60) on a ZnTPP/Fe(001)–p(1 × 1)O substrate: observation of a quasi-freestanding C(60) monolayer
  8. 4348
    “…The charge transfer for the Au cluster significantly improved by reducing the HOMO–LUMO energy gap from 3.67 eV to 0.91 eV after doping with Cu atoms. …”
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    Insights into the nonlinear optical (NLO) response of pure Aum (2 ≥ m ≤ 7) and copper-doped Au(m)–xCu(x) clusters
  9. 4349
    “…Here we show that SLITRK1 suppresses noradrenergic projections in the neonatal prefrontal cortex, and SLITRK1 functions are impaired by SLITRK1 mutations in patients with schizophrenia (S330A, a revertant of Homo sapiens-specific residue) and bipolar disorder (A444S). …”
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    SLITRK1-mediated noradrenergic projection suppression in the neonatal prefrontal cortex
  10. 4350
    “…DFT/TD-DFT calculations through B3LYP/6-311G++ level of theory were applied to provide comparable theoretical data along with MEP map and electronic energy gap of HOMO → LUMO. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11164-022-04831-5.…”
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    One-pot synthesis, molecular docking, ADMET, and DFT studies of novel pyrazolines as promising SARS-CoV-2 main protease inhibitors
  11. 4351
    “…The sequences of 13 vertebrate cyt b amplicons were considered informative, exhibiting similarity and clustering with the following six vertebrate species: Dasyprocta leporina (1), Cuniculus paca (1), Tamandua tetradactyla (4), Choloepus didactylus (4), Pteroglossus aracari aracari (2), Homo sapiens (1). The samples of D. leporina and C. paca were obtained from the CDC canopy, whereas the others were by aspiration from tree bases. …”
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    Blood Feeding Sources of Nyssomyia antunesi (Diptera: Psychodidae): A Suspected Vector of Leishmania (Kinetoplastida: Trypanosomatidae) in the Brazilian Amazon
  12. 4352
    “…The unique nature of these cells still deserves attention from the scientific community. Telocytes make homo- and heterocellular contact with myocytes, immunocytes and nerves, have their own immunohistochemical and secretome profiles and thus might regulate local regenerative processes including angiogenesis and fibrosis. …”
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    Identification of PDGFRα+ cells in uterine fibroids – link between angiogenesis and uterine telocytes
  13. 4353
    “…Neutralizing antibody ID50 titers induced by mos-tri-RBD were substantially higher than those elicited by homo-tri-RBD (containing homologous RBDs from prototype strain) or the BIBP inactivated COVID-19 vaccine (BBIBP-CorV). …”
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    A mosaic-type trimeric RBD-based COVID-19 vaccine candidate induces potent neutralization against Omicron and other SARS-CoV-2 variants
  14. 4354
    “…Here, we show that Pd-H in the presence of an N-heterocyclic carbene ligand and an alkene regulator enables transfer-dehydroaromatization, avoiding the homo-disproportionation pathway. The desired product is obtained with up to 99:1 selectivity, and the exo-to-endo olefin isomerization can be carried out in one pot. …”
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    (NHC)Pd(II) hydride-catalyzed dehydroaromatization by olefin chain-walking isomerization and transfer-dehydrogenation
  15. 4355
    “…Its crucial importance is denounced by the high percentage of amino acid sequence identity between very different species (Homo sapiens, Drosophila melanogaster, Rattus norvegicus, Danio rerio, Canis lupus familiaris, Gekko japonicus). …”
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    p53: From Fundamental Biology to Clinical Applications in Cancer
  16. 4356
    por Xiao, Yao, MacRae, Ian J
    Publicado 2022
    “…Replacing this loop with the equivalent loop from Homo sapiens AGO2 (HsAGO2) changes AtAGO10 miRNA loading behavior such that 3′ region mismatches are ignored and mismatches opposite the guide 5′ end instead drive loading, as in HsAGO2. …”
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    The molecular mechanism of microRNA duplex selectivity of Arabidopsis ARGONAUTE10
  17. 4357
    “…We designed a selection protocol that maximizes the efficiency of the proteomics analyses by excluding particularly compromised fragments (e.g. from taphonomic processes), and that aims to identify new human fragments by favouring bones showing morphological traits more similar to Homo. ZooMS consistently provided taxonomic information in agreement with the faunal spectra outlined by traditional zooarchaeology. …”
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    Integrating ZooMS and zooarchaeology: New data from the Uluzzian levels of Uluzzo C Rock Shelter, Roccia San Sebastiano cave and Riparo del Broion
  18. 4358
    “…The obtained LMW-PLLA and scPLA powders with a nearly spherical shape showed complete homo- and stereocomplex crystallites, respectively. …”
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    Enhancement in Crystallizability of Poly(L-Lactide) Using Stereocomplex-Polylactide Powder as a Nucleating Agent
  19. 4359
    “…In the present study, we comprehensively analyzed the differential expression, immune infiltration, and interactions of EMS-related genes in three Homo sapiens datasets. Our results identified 332 differentially expressed genes (DEGs) associated with EMS. …”
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    Five immune-related genes as diagnostic markers for endometriosis and their correlation with immune infiltration
  20. 4360
    por Balzeau, Antoine, Albessard-Ball, Lou, Kubicka, Anna Maria, Filippo, Andréa, Beaudet, Amélie, Santos, Elena, Bienvenu, Thibault, Arsuaga, Juan-Luis, Bartsiokas, Antonis, Berger, Lee, Bermúdez de Castro, José María, Brunet, Michel, Carlson, Kristian J., Daura, Joan, Gorgoulis, Vassilis G., Grine, Frederick E., Harvati, Katerina, Hawks, John, Herries, Andy, Hublin, Jean-Jacques, Hui, Jiaming, Ives, Rachel, Joordens, Josephine A., Kaifu, Yousuke, Kouloukoussa, Mirsini, Léger, Baptiste, Lordkipanidze, David, Margvelashvili, Ann, Martin, Jesse, Martinón-Torres, María, May, Hila, Mounier, Aurélien, du Plessis, Anton, Rae, Todd, Röding, Carolin, Sanz, Montserrat, Semal, Patrick, Stratford, Dominic, Stringer, Chris, Tawane, Mirriam, Temming, Heiko, Tsoukala, Evangelia, Zilhão, João, Zipfel, Bernhard, Buck, Laura T.
    Publicado 2022
    “…We also observed a covariation between the size and shape of the sinuses and the underlying frontal lobes in hominin species from at least the appearance of Homo erectus. Our results additionally undermine hypotheses stating that hominin frontal sinuses were directly affected by biomechanical constraints resulting from either chewing or adaptation to climate. …”
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    Frontal sinuses and human evolution
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