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  1. 4601
    “…Homo and heterozygote cx3cr1 mutant mice, which harbor a green fluorescent protein (EGFP) in their cx3cr1 loci, represent a widely used animal model to study microglia and peripheral myeloid cells. …”
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    Microglial CX(3)CR1 promotes adult neurogenesis by inhibiting Sirt 1/p65 signaling independent of CX(3)CL1
  2. 4602
    “…We previously showed that the two alpha satellite arrays of Homo sapiens Chromosome 17 (HSA17), D17Z1 and D17Z1-B, behave as centromeric epialleles, that is, the centromere, defined by chromatin containing the centromeric histone variant CENPA and recruitment of other centromere proteins, can form at either D17Z1 or D17Z1-B. …”
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    Genomic variation within alpha satellite DNA influences centromere location on human chromosomes with metastable epialleles
  3. 4603
    “…The optical band gap becomes narrower (from 1.94 to 1.82 eV) and the HOMO energy levels increased (from −5.68 to −5.34 eV) with the increase of the length of the π-conjugated bridge. …”
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    Effect of the π-conjugation length on the properties and photovoltaic performance of A–π–D–π–A type oligothiophenes with a 4,8-bis(thienyl)benzo[1,2-b:4,5-b′]dithiophene core
  4. 4604
    por Bayle, Enyew A.
    Publicado 2016
    “…The most electropositivity and the lowest percentage contribution to the HOMO are shown at C(2) of quinoline compared to the other carbon atoms. …”
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    Modeling the transition state structure to probe a reaction mechanism on the oxidation of quinoline by quinoline 2-oxidoreductase
  5. 4605
    “…Together these findings imply significant differences in both locomotor behavior and ecology between australopiths and later Homo.…”
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    Limb Bone Structural Proportions and Locomotor Behavior in A.L. 288-1 ("Lucy")
  6. 4606
    “…Using the concept of gap-determining LUMO–HOMO frontier states to avoid HOMOs and LUMOs localized at the zigzag edges, we can predict with very high accuracy the recently measured band gaps of AGNRs of widths N = 7 and N = 13. …”
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    Interrelation of Aromaticity and Conductivity of Graphene Dots/Antidots and Related Nanostructures
  7. 4607
    “…In this study, four homo/heterogenous polysaccharides (HBSS, CHSS, DASS, and CASS) extracted from peony seed dreg with respective molecular weights of 3467, 4677, 229, and 56 kDa were evaluated for anti-cancerous attributes in prostate cancer cells (Pc-3), colon cancer cells (HCT-116), human breast cancer cells (MCF-7), cervical cancer (Hela cells) and human embryonic kidney 293 (HEK 293) cells as control. …”
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    Anti-Cancerous Potential of Polysaccharide Fractions Extracted from Peony Seed Dreg on Various Human Cancer Cell Lines Via Cell Cycle Arrest and Apoptosis
  8. 4608
    “…Gap junctions (GJs) in astrocytes and glioma cells are important channels for cell-to-cell communication that contribute to homo- and heterocellular coupling. According to recent studies, heterocellular gap-junctional communication (H-GJC) between glioma cells and their surrounding environment enhances glioma progression. …”
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    Dexamethasone and levetiracetam reduce hetero-cellular gap-junctional coupling between F98 glioma cells and glial cells in vitro
  9. 4609
    por Li, Wei, Li, Jiuyan, Liu, Di, Li, Deli, Zhang, Dan
    Publicado 2016
    “…Direct linking of the dual n-type units not only pulls the LUMOs down, but also keeps the HOMO levels shallow, and leads to high triplet energies (2.78–2.86 eV) and small singlet-triplet energy differences (0.23–0.35 eV). …”
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    Dual n-type units including pyridine and diphenylphosphine oxide: effective design strategy of host materials for high-performance organic light-emitting diodes
  10. 4610
    “…Non-structural carbohydrate analysis demonstrated that starch concentrations in ‘M9’ roots, stems and grafted ‘Royal Gala’ (‘RG’) scions were double that of equivalent tissues from ‘RG’ homo-grafted trees (‘RG’/‘RG’). Fructose and glucose concentrations were much lower in all three tissues of the ‘RG’/‘M9’ trees. …”
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    Apple dwarfing rootstocks exhibit an imbalance in carbohydrate allocation and reduced cell growth and metabolism
  11. 4611
    “…However, this negative association happened in Africa (OR, 0.59; 95% CI, 0.40–0.86; p = 0.007) but not in Asia (OR, 1.24; 95% CI, 0.96–1.61; p = 0.10), and in the heterozygotes (OR, 0.70; 95% CI, 0.57–0.87; p = 0.001) but not the homo/hemizygous (OR, 0.70; 95% CI, 0.46–1.07; p = 0.10). …”
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    Association of glucose-6-phosphate dehydrogenase deficiency and malaria: a systematic review and meta-analysis
  12. 4612
    “…Our results revealed that during maturation, the metabolic levels of N2-acetyl-L-ornithine, 3,1'-(OH)2-Gamma-carotene, (5Z,7E)-(1S,3R)-24,24-difluoro-24a-homo-9,10-seco-5,7,10(19)-cholestatrien-1,3,25-triol, stoloniferone O, PA(O-18:0/12:0), PA(P-16:0/14:0), PA(P-16:0/16:(19Z)) and PA(P-16:0/17:2(9Z,12Z)) were suppressed in both differentiated and undifferentiated mycelia. …”
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    Metabolites contributing to Rhizoctonia solani AG-1-IA maturation and sclerotial differentiation revealed by UPLC-QTOF-MS metabolomics
  13. 4613
    “…A 3-D structural model of the ClPDI has been created based on the known crystal structure of Homo sapiens (PDB ID: 3F8U_A). The enzyme has two putative active sites comprising the redox-active disulfides between residues 60–63 and 405–408 (motif CGHC). …”
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    Lemon protein disulfide isomerase: cDNA cloning and biochemical characterization
  14. 4614
    “…In addition, we observed strong, sequence-specific binding of 1H6 by ELISA to immobilized single stranded poly(T) DNA but not to immobilized poly(C) or poly(A) homo-polymers. Cross-reactivity of 1H6 to poly(T) was not measured in solution using MST. 1H6 was furthermore found to bind to selected areas on DNA fibers but only after DNA denaturation. …”
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    Guanine quadruplex monoclonal antibody 1H6 cross-reacts with restrained thymidine-rich single stranded DNA
  15. 4615
    “…This method predicted 43 transcriptional regulator families in Arabidopsis thaliana, 7 families in Drosophila melanogaster, and 9 families in Homo sapiens. Literature curation validated 12 of the predicted families to be involved in transcriptional regulation. …”
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    Systematic discovery of novel eukaryotic transcriptional regulators using sequence homology independent prediction
  16. 4616
    “…Besides facilitating the extracellular secretion, sfGFP fusion proteins can also be correctly folded and formed the active complex protein structure, including the trimetric human ARG1 and homo-hexametric GAD. This is the first report that sfGFP can guide the secretion of recombinant proteins out of the cells from cytoplasm in E. coli without affecting their conformation and function.…”
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    Non-peptide guided auto-secretion of recombinant proteins by super-folder green fluorescent protein in Escherichia coli
  17. 4617
    “…Sulfide clusterfullerenes with a fullerene-based HOMO have more positive oxidation potentials. The metal-based oxidation of Sc(2)@C(82)-C(3v) is confirmed by the EPR spectrum of the cation radical [Sc(2)@C(82)-C(3v)](+) generated by chemical oxidation in solution. …”
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    Confining the spin between two metal atoms within the carbon cage: redox-active metal–metal bonds in dimetallofullerenes and their stable cation radicals†
  18. 4618
    “…To elucidate the overall activation paradigm via allosteric versus orthosteric sites, we used highly homologous, but homo-oligomeric, ρ(1) receptors that are contrastingly insensitive to anaesthetics and respond partially to several full GABA α(1)β(2)γ(2) receptor agonists. …”
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    Orthosteric- versus allosteric-dependent activation of the GABA(A) receptor requires numerically distinct subunit level rearrangements
  19. 4619
    “…We focused on four miRNA clusters composed of miRNA members of the same family, homo-clusters or different families, hetero-clusters. …”
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    CRISPR/Cas9 editing reveals novel mechanisms of clustered microRNA regulation and function
  20. 4620
    “…Based on its crystal structure, PHL forms a seven-bladed β-propeller assembling into a homo-dimer with an inter-subunit disulfide bridge. …”
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    Characterization of novel bangle lectin from Photorhabdus asymbiotica with dual sugar-binding specificity and its effect on host immunity
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