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  1. 5341
    “…Moreover, IVAX-1 induces identical homo- and heterosubtypic IgG and IgA cross-reactivity profiles when administered intranasally. …”
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    Magnitude and breadth of antibody cross-reactivity induced by recombinant influenza hemagglutinin trimer vaccine is enhanced by combination adjuvants
  2. 5342
    “…Complexes 6–8 and 11 display HOMO delocalization throughout the metal–heterocycle-metal skeleton. …”
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    Electronic Communication in Binuclear Osmium- and Iridium-Polyhydrides
  3. 5343
    “…Up to four bloodmeal sources were detected in a single triatomine (I. nebulifer, Homo sapiens, C. lupus familiaris, and S. carolinensis). …”
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    Characterization of triatomine bloodmeal sources using direct Sanger sequencing and amplicon deep sequencing methods
  4. 5344
    “…The FMO analysis revealed the uniform dispersal of charge density entirely along the highest occupied (HOMO) and lowest unoccupied (LUMO) molecular orbitals in newly constructed moieties. …”
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    Molecular Modeling of Pentacyclic Aromatic Bislactam-Based Small Donor Molecules by Altering Auxiliary End-Capped Acceptors to Elevate the Photovoltaic Attributes of Organic Solar Cells
  5. 5345
    “…Archaeological and genomic evidence suggest that modern Homo sapiens have roamed the planet for some 300–500 thousand years. …”
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    African mitochondrial haplogroup L7: a 100,000-year-old maternal human lineage discovered through reassessment and new sequencing
  6. 5346
    por Hunt, Andrew C., Case, James Brett, Park, Young-Jun, Cao, Longxing, Wu, Kejia, Walls, Alexandra C., Liu, Zhuoming, Bowen, John E., Yeh, Hsien-Wei, Saini, Shally, Helms, Louisa, Zhao, Yan Ting, Hsiang, Tien-Ying, Starr, Tyler N., Goreshnik, Inna, Kozodoy, Lisa, Carter, Lauren, Ravichandran, Rashmi, Green, Lydia B., Matochko, Wadim L., Thomson, Christy A., Vögeli, Bastian, Krüger, Antje, VanBlargan, Laura A., Chen, Rita E., Ying, Baoling, Bailey, Adam L., Kafai, Natasha M., Boyken, Scott E., Ljubetič, Ajasja, Edman, Natasha, Ueda, George, Chow, Cameron M., Johnson, Max, Addetia, Amin, Navarro, Mary Jane, Panpradist, Nuttada, Gale, Michael, Freedman, Benjamin S., Bloom, Jesse D., Ruohola-Baker, Hannele, Whelan, Sean P. J., Stewart, Lance, Diamond, Michael S., Veesler, David, Jewett, Michael C., Baker, David
    Publicado 2022
    “…We found the broadest efficacy with a homo-trimeric version of the 75-residue angiotensin converting enzyme 2 (ACE2) mimic AHB2 (TRI2–2) designed to geometrically match the trimeric spike architecture. …”
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    Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice
  7. 5347
    “…Moreover, this was asserted by profound calculations of HOMO (highest occupied molecular orbital) and LUMO (lowest unoccupied molecular orbital) energy levels, the molecular electrostatic potential (MEP), and natural bond orbital (NBO) that had been studied for the TPA-sensitizers. …”
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    Synthesis of innovative triphenylamine-functionalized organic photosensitizers outperformed the benchmark dye N719 for high-efficiency dye-sensitized solar cells
  8. 5348
    “…Acute myeloid leukemia (AML) is a malignant disease of immature myeloid cells and the most prevalent acute leukemia among adults. The oncogenic homo-tetrameric fusion protein RUNX1/ETO results from the chromosomal translocation t(8;21) and is found in AML patients. …”
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    Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects
  9. 5349
    “…Four hub genes were identified: amyloid beta precursor protein binding family B member 1 (APBB1), Homo sapiens armadillo repeat containing X-linked 1 (ARMCX1), DAZ interacting zinc finger protein 1 (DZIP1), and methionine sulfoxide reductase B3 (MSRB3). …”
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    Exploration of hub genes, lipid metabolism, and the immune microenvironment in stomach carcinoma and cholangiocarcinoma
  10. 5350
    “…ABSTRACT: The ‘domestication syndrome’ defines a suite of features that domesticated animals possess as the result of the artificial selection operated by Homo sapiens since the Neolithic. An interesting anthropological question is whether such features, including increased tameness and reduced aggression, apply to all domesticated forms. …”
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    Does the Domestication Syndrome Apply to the Domestic Pig? Not Completely
  11. 5351
    “…Additionally, 16 circRNAs were highly conserved among A. m. ligustica, Apis cerana cerana, and Homo sapiens. In the Am7CK vs. Am7T (Am10CK vs. Am10T) comparison group, 168 (306) differentially expressed circRNAs (DEcircRNAs) were identified. …”
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    Deciphering the CircRNA-Regulated Response of Western Honey Bee (Apis mellifera) Workers to Microsporidian Invasion
  12. 5352
    “…During the adsorption-controlled oxidation process of the axitinib, the electrons are transferred via the highest occupied molecular orbital (HOMO) localized on the iron oxide moiety to the lowest unoccupied molecular orbital (LUMO) of the MWCNT/GCE surface.…”
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    Detection of Axitinib Using Multiwalled Carbon Nanotube-Fe(2)O(3)/Chitosan Nanocomposite-Based Electrochemical Sensor and Modeling with Density Functional Theory
  13. 5353
    “…In the filtering, we used AD for search keywords, Homo sapiens for species selection, and established a sample size of > 20 for each data set, and each data set contains Including the normal group and AD group. …”
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    Identification of feature genes and pathways for Alzheimer's disease via WGCNA and LASSO regression
  14. 5354
    “…The experimental treatments included the AMF treatments inoculated with (M(+)) or without (M(-)) fungus Glomus etunicatum; the substrate patchiness treatments involved different sizes of the homogeneous patch (Homo), the heterogeneous large patch (Hetl), and the heterogeneous small patch (Hets); the substrate gravel treatments in the inner patch involved the free gravel (FG), the low gravel (LG) 20% in 80% soil, and the high gravel (HG) 40% in 60% soil. …”
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    Effects of AMF on plant nutrition and growth depend on substrate gravel content and patchiness in the karst species Bidens pilosa L
  15. 5355
    “…Lipopolysaccharides (LPSs) are microbiome-derived glycolipids that are among the most potent pro-inflammatory neurotoxins known. In Homo sapiens, the major sources of LPSs are gastrointestinal (GI)-tract-resident facultative anaerobic Gram-negative bacilli, including Bacteroides fragilis and Escherichia coli. …”
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    Lipopolysaccharides (LPSs) as Potent Neurotoxic Glycolipids in Alzheimer’s Disease (AD)
  16. 5356
    “…DFT calculations revealed that the carbene coordination modulates the frontier orbitals (i.e. HOMO/LUMO) of diphosphenes 2a and 2b, thereby affecting the reactivity of 3a and 3b. …”
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    Modulating the frontier orbitals of L(X)Ga-substituted diphosphenes [L(X)GaP](2) (X = Cl, Br) and their facile oxidation to radical cations
  17. 5357
    “…The docking was performed against the COX2 targeting protein (PDB code: 5IKT Homo sapiens). The binding energies were −7.52, −9.41, −9.51, −8.09, −10.04, and −8.05 kcal/mol for HL and the Co, Ni, Cu, Sm, and Gd complexes, respectively, which suggests the enhancement of anti-inflammatory behaviors compared with the binding energy of ibuprofen (−5.38 kcal/mol). …”
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    A Novel Ibuprofen Derivative and Its Complexes: Physicochemical Characterization, DFT Modeling, Docking, In Vitro Anti-Inflammatory Studies, and DNA Interaction
  18. 5358
    “…It is important to stress that the second one, Homo sapiens leptin receptor overlapping transcript (LEPROT) transcript variant 1 mRNA, is known to be inversely proportional to sepsis (its causal effect is negative). …”
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    541. In Silico Modeling by Causal Inference for Identifying Biomarkers of Sepsis
  19. 5359
    “…Our study aimed to perform bioinformatics analysis on S. pombe proteins and their sequence homologs in Aspergillus flavus (af), Saccharomyces cerevisiae (sc), and Homo sapiens (hs) to understand the role of spGrx4, spFep1, and spPhp4 in maintaining iron homeostasis. …”
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    Schizosaccharomyces pombe Grx4, Fep1, and Php4: In silico analysis and expression response to different iron concentrations
  20. 5360
    “…Further simulations and experimental analysis support a novel mechanism, homo-insufficiency under insufficient background (HoIIB), underlying heterosis. …”
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    Large-scale genomic and transcriptomic profiles of rice hybrids reveal a core mechanism underlying heterosis
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