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5481por Wu, Wenxian, Wang, Xiaojing, Sun, Yadong, Berleth, Niklas, Deitersen, Jana, Schlütermann, David, Stuhldreier, Fabian, Wallot-Hieke, Nora, José Mendiburo, María, Cox, Jan, Peter, Christoph, Bergmann, Ann Kathrin, Stork, Björn“…Abbreviations: ACACA/ACC: acetyl-CoA carboxylase alpha; AMPK: AMP-activated protein kinase; ATG: autophagy-related; BECN1: beclin 1; GFP: green fluorescent protein; EBSS: Earle’s balanced salt solution; Hs: Homo sapiens; KO: knockout; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MEF: mouse embryonic fibroblast; MLKL: mixed lineage kinase domain like pseudokinase; Mm: Mus musculus; MTOR: mechanistic target of rapamycin kinase; MVB: multivesicular body; PIK3C3/VPS34: phosphatidylinositol 3-kinase catalytic subunit type 3; PIK3R4/VPS15: phosphoinositide-3-kinase regulatory subunit 4; PLA: proximity ligation assay; PRKAA1: protein kinase AMP-activated catalytic subunit alpha 1; PRKAA2: protein kinase AMP-activated catalytic subunit alpha 2; PRKAB2: protein kinase AMP-activated non-catalytic subunit beta 2; PRKAG1: protein kinase AMP-activated non-catalytic subunit gamma 1; PtdIns3K: phosphatidylinositol 3-kinase; PtdIns3P: phosphatidylinositol-3-phosphate; RIPK1: receptor interacting serine/threonine kinase 1; RIPK3: receptor interacting serine/threonine kinase 3; SNAP29: synaptosome associated protein 29; SNARE: soluble N-ethylmaleimide-sensitive factor attachment protein receptor; SQSTM1/p62: sequestosome 1; STK11/LKB1: serine/threonine kinase 11; STX7: syntaxin 7; STX17: syntaxin 17; TAX1BP1: Tax1 binding protein 1; TNF: tumor necrosis factor; ULK1: unc-51 like autophagy activating kinase 1; VAMP8: vesicle associated membrane protein 8; WT: wild-type.…”
Publicado 2021
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5482“…To illustrate the wide applicability of our approach, we analyzed semi-artificial and published circSeq data from the model organisms Homo sapiens and Arabidopsis thaliana, and generated circSeq reads from the non-model crop plant Beta vulgaris. …”
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5483por Jønsson, Viggo, Awan, Haneef, Jones, Neil Deaton, Johannesen, Tom Børge, Thøgersen, Klaus, Steig, Bjarni á, Andorsdottir, Gudrid, Tjønnfjord, Geir Erland“…Although leukemias, lymphomas and myelomas are potentially fatal diseases, this non-Mendelian distribution and amplification hardly play any quantitative role in the survival of Homo sapiens, because these diseases mostly occur after fertile age.…”
Publicado 2022
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5484por Ali, Amjad, Naveed, Ahmad, Shehzad, Khurram, Aziz, Tariq, Rasheed, Tahir, Moradian, Jamile Mohammadi, Hassan, Mobashar, Rahman, Abdul, Zhiqiang, Fan, Guo, Li“…The active center [Zr]/[*C] fraction considerably increased in the initial (t(p)) 840 s, and subsequently tended to the steady stage of 33%, which is lower than previously reported E homo- and E/P copolymerization. The lower [C*]/[Zr] in both the early and stable stages, decrease in VNB mol%, and R(p) with t(p) can be associated with the more significant fraction of Cp(2)Zr–CH(2)CH(3)-type dormant site by the β-agostic hydrogen interaction with the Cp(2)Zr metal. …”
Publicado 2022
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5485“…[Image: see text] Di- and poly-homo/heteronuclear complexes have great potential as anticancer drugs. …”
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5486“…To choose suitable HTMs, it was displayed that both of lowest unoccupied molecular orbital (LUMO) and highest occupied molecular orbital (HOMO) energies of molecules were located higher than those of CH(3)NH(3)PbI(3) (MAPbI(3)) perovskite as they were able to transfer holes from the MAPbI(3) toward Ag cathode. …”
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5487“…The catastrophic consequences of the SARS-CoV-2 pandemic clearly indicate that homo sapiens appeared to be unable to effectively resist the onslaught of the coronavirus. …”
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5488por Sakamoto, Takuma, Sinzeki, Shun, Kakinuma, Shunsuke, Ishihara, Eri, Tabunoki, Hiroko“…We annotated P. auratus transcripts using Homo sapiens and Drosophila melanogaster genes as references; 50.5% of P. auratus transcripts were assigned to H. sapiens genes, and 54.0% of P. auratus transcripts were assigned to D. melanogaster genes. …”
Publicado 2022
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5489“…Totally, 300 distinct STs were identified among 4386 strains with ST11 (n = 477, 10.9%) being the most predominant one followed by ST258 (n = 410, 9.4%). Homo sapiens (2696/4386, 61.5%) was the main host for blaOXA-carrying K. pneumoniae isolates. …”
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5490por Kariuki, Silvia N, Macharia, Alexander W, Makale, Johnstone, Nyamu, Wilfred, Hoffman, Stephen L, Kapulu, Melissa C, Bejon, Philip, Rayner, Julian C, Williams, Thomas N“…BACKGROUND: The long co-evolution of Homo sapiens and Plasmodium falciparum has resulted in the selection of numerous human genetic variants that confer an advantage against severe malaria and death. …”
Publicado 2023
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5491por Ejaz, Syeda Abida, Farid, Aftab, Zargar, Seema, Channar, Pervaiz Ali, Aziz, Mubashir, Wani, Tanveer A., Attaullah, Hafiz Muhammad, Ujhan, Rabail, Tehzeeb, Arfa, Saeed, Aamer, Ali, Hafiz Saqib, Erben, Mauricio F.“…Analysis via (1)H-NMR and (13)C-NMR spectroscopy, as well as density functional considerations through B3LYP functional correlation with 6-311 + + G(d) and 6-31G(d) basis set, revealed the observed LUMO/HOMO energies and charge transfer within the molecule. …”
Publicado 2023
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5492por Gber, Terkumbur E., Louis, Hitler, Ngana, Obinna C., Amodu, Ismail O., Ekereke, Ernest E., Benjamin, Innocent, Adalikwu, Stephen A., Adeyinka, Adedapo“…Surfaces decorated with yttrium and zirconium exhibited decreased energies of the highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO), as well as decreased energy gap, indicating increased conductivity and sensitivity. …”
Publicado 2023
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5493por Bachner-Melman, Rachel, Dina, Christian, Zohar, Ada H, Constantini, Naama, Lerer, Elad, Hoch, Sarah, Sella, Sarah, Nemanov, Lubov, Gritsenko, Inga, Lichtenberg, Pesach, Granot, Roni, Ebstein, Richard P“…Dancing, which is integrally related to music, likely has its origins close to the birth of Homo sapiens, and throughout our history, dancing has been universally practiced in all societies. …”
Publicado 2005
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5494por Kilani, Hajer, Abbassi, Mohamed Salah, Ferjani, Sana, Mansouri, Riadh, Sghaier, Senda, Ben Salem, Rakia, Jaouani, Imen, Douja, Gtari, Brahim, Sana, Hammami, Salah, Ben Chehida, Noureddine, Boubaker, Ilhem Boutiba-Ben“…We conclude that these avian ESBL-producing E. coli isolates show homo- and heterogenic genetic background and that plasmids harboring ESBL genes could be involved in the dissemination of this resistance phenotype.…”
Publicado 2015
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5495por Börstler, Jessica, Jöst, Hanna, Garms, Rolf, Krüger, Andreas, Tannich, Egbert, Becker, Norbert, Schmidt-Chanasit, Jonas, Lühken, Renke“…The most common host species were roe deer (Capreolus capreolus; 258 mosquito specimens, 33.3 % of all mosquito specimens, 65 % of all mosquito species), humans (Homo sapiens; 152, 19.6 %, 90 %), cattle (Bos taurus; 101, 13.0 %, 60 %), and wild boar (Sus scrofa; 116, 15.0 %, 50 %). …”
Publicado 2016
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5496por Balsalobre, Thiago Willian Almeida, da Silva Pereira, Guilherme, Margarido, Gabriel Rodrigues Alves, Gazaffi, Rodrigo, Barreto, Fernanda Zatti, Anoni, Carina Oliveira, Cardoso-Silva, Cláudio Benício, Costa, Estela Araújo, Mancini, Melina Cristina, Hoffmann, Hermann Paulo, de Souza, Anete Pereira, Garcia, Antonio Augusto Franco, Carneiro, Monalisa Sampaio“…These markers were distributed throughout 223 linkage groups, which were clustered in 18 homo(eo)logous groups (HGs), with a cumulative map length of 3,682.04 cM and an average marker density of 3.70 cM. …”
Publicado 2017
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5497por Xiong, Shuting, Wang, Ying, Yao, Mingdong, Liu, Hong, Zhou, Xiao, Xiao, Wenhai, Yuan, Yingjin“…Through screening CYP11B1s (with mutagenesis at N-terminus) from nine sources, Homo sapiens CYP11B1 mutant (G25R/G46R/L52 M) achieved the highest 21-DF transformation rate at 10.6 mg/L/h. …”
Publicado 2017
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5498por Soares, Cleverson T., Trombone, Ana P. F., Fachin, Luciana R. V., Rosa, Patricia S., Ghidella, Cássio C., Ramalho, Rodrigo F., Pinilla, Mabel G., Carvalho, Alex F., Carrara, Dirce N., Soares, Fernando A., Belone, Andrea F. F.“…Punch biopsies were collected from the borders of leprosy lesions (10 tuberculoid, 10 borderline tuberculoid, 10 borderline borderline, 10 borderline lepromatous, 4 lepromatous, 14 R1, and 9 R2) and from 9 HCs. miRNA expression profiles were obtained using the Agilent Microarray platform with miRBase, which consists of 1,368 Homo sapiens (hsa)-miRNA candidates. TaqMan quantitative real-time reverse transcription polymerase chain reaction (RT-PCR) was used to validate differentially expressed miRNAs. …”
Publicado 2017
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5499por Shahhosseini, Nariman, Friedrich, Johannes, Moosa-Kazemi, Seyed Hassan, Sedaghat, Mohammad Mehdi, Kayedi, Mohammad Hassan, Tannich, Egbert, Schmidt-Chanasit, Jonas, Lühken, Renke“…The most commonly detected hosts of the four most abundant mosquito species were humans (Homo sapiens; 224 mosquito specimens, 40.9% of all mosquito specimens), cattle (Bos taurus; 171, 31.2%) and ducks (Anas spp.; 75, 13.7%). …”
Publicado 2018
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5500por Kleinpeter, Patricia, Remy-Ziller, Christelle, Winter, Eline, Gantzer, Murielle, Nourtier, Virginie, Kempf, Juliette, Hortelano, Julie, Schmitt, Doris, Schultz, Huguette, Geist, Michel, Brua, Catherine, Hoffmann, Chantal, Schlesinger, Yasmin, Villeval, Dominique, Thioudellet, Christine, Erbs, Philippe, Foloppe, Johann, Silvestre, Nathalie, Fend, Laetitia, Quemeneur, Eric, Marchand, Jean-Baptiste“…In this article we report that the M2 protein encoded by the vaccinia virus is secreted as a homo-oligomer by infected cells and binds two central costimulation molecules, CD80 (B7-1) and CD86 (B7-2). …”
Publicado 2019
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