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  1. 761
    por Alafari, Hayat, Alenzi, Faris Q.
    Publicado 2020
    “…These deletions including: (*C-1960-1961 ca/-- del in hbb5) and (*c-519C<T homo, *c-390C<T homo in hbb6) were the highest among beta-thalassemia in the study, which indicates a strong sign of injury associated with the disease. …”
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    Biochemical and molecular analysis of the beta-globin gene and LCR region on Saudi β-thalassemia patients
  2. 762
    “…Homo-40S displayed mild growth defects along with high sensitivity to the translation inhibitor paromomycin and a significantly increased stop codon readthrough. …”
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    Engineering and functional analysis of yeast with a monotypic 40S ribosome subunit
  3. 763
    “…We found that there are two types of miRNA clusters, i.e. homo-clusters that contain miRNAs of the same family and hetero-clusters that contain miRNAs of various families. …”
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    Regulatory coordination of clustered microRNAs based on microRNA-transcription factor regulatory network
  4. 764
    “…Further, the median survival of B(homo)KA mice was significantly shorter at 24 weeks when compared to the median survival of ≥40 weeks in B(het)KA mice and approximately 50 weeks in B(homo)A and KA mice (p < 0.001). …”
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    Oncogenic KRAS Requires Complete Loss of BAP1 Function for Development of Murine Intrahepatic Cholangiocarcinoma
  5. 765
    por Stibel, Jeff Morgan
    Publicado 2022
    “…Across regional and global paleoclimate records, brain size in Homo averaged significantly lower during periods of climate warming as compared to cooler periods. …”
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    Climate Change Influences Brain Size in Humans
  6. 766
    “…The electronic structure of a stable Au(20) cluster can be modulated by incorporating Ag, and the HOMO–LUMO gap of Au(20−)(n)Ag(n) clusters is modulated due to the incorporation of Ag electronic states in the HOMO and LUMO. …”
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    First-Principles Investigation of Ag-Doped Gold Nanoclusters
  7. 767
    “…Acetyl-mimetic mutants of RIG-I do not form virus-induced homo-oligomers, revealing that acetyl-lysine residues of the RIG-I repressor domain prevent assembly to active homo-oligomers. …”
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    Regulation of Retinoic Acid Inducible Gene-I (RIG-I) Activation by the Histone Deacetylase 6
  8. 768
    “…In sharp contrast, H-bonding driven homo-polymers of A and D are formed by just replacing the bulky chains of the A monomer with linear hydrocarbons. …”
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    Steric ploy for alternating donor–acceptor co-assembly and cooperative supramolecular polymerization
  9. 769
    “…Met35 can be susceptible to persulfidation through its substitution to homoCys residue under the condition of oxidative stress. …”
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    Synthetic and biochemical studies on the effect of persulfidation on disulfide dimer models of amyloid β42 at position 35 in Alzheimer's etiology
  10. 770
    “…PATIENTS AND METHODS: We identified 191 consecutive DES ISR lesions from 183 patients who required clinically driven revascularization and divided them into three groups according to the treatment: 38 lesions were treated with POBA, 38 with HOMO-DES, and 115 with HETERO-DES. RESULTS: The incidence of target lesion revascularization (TLR) was 42.1% (16/38), 15.8% (6/38), and 16.5% (19/115) in the POBA, HOMO-DES, and HETERO-DES groups (POBA vs. …”
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    Switching types of drug-eluting stents does not prevent repeated in-stent restenosis in patients with coronary drug-eluting stent restenosis
  11. 771
    “…Extant human standards overestimate age at death in hominins predating Homo sapiens, and should not be applied to other fossil taxa. …”
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    Dental Ontogeny in Pliocene and Early Pleistocene Hominins
  12. 772
    “…RESULTS: According to HOMO-LUMO gap and the chemical hardness the most stable compounds are alprenolol, bisoprolol and esmolol. …”
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    Global chemical reactivity parameters for several chiral beta-blockers from the Density Functional Theory viewpoint
  13. 773
    “…Applications using CRY2–CIB1 interaction desire minimal CRY2 homo-oligomerization to avoid unintended complications, while those utilizing CRY2–CRY2 interaction prefer robust homo-oligomerization. …”
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    Understanding CRY2 interactions for optical control of intracellular signaling
  14. 774
    “…Invoking this argument, molecular junctions based on alkane monothiols (CnT) can be expected to exhibit high RRs; the HOMO of these molecules is localized on the thiol terminal group bonded to one electrode. …”
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    Why one can expect large rectification in molecular junctions based on alkane monothiols and why rectification is so modest
  15. 775
    “…In the off-state of the pathway ApoER2 and VLDLR form homo or hetero-di/oligomers. Upon binding of full length Reelin ApoER2 and VLDLR homo-oligomers are rearranged to higher order receptor clusters which leads to Dab1 phosphorylation. …”
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    Differential Action of Reelin on Oligomerization of ApoER2 and VLDL Receptor in HEK293 Cells Assessed by Time-Resolved Anisotropy and Fluorescence Lifetime Imaging Microscopy
  16. 776
    “…The results showed that Acid blue 113 with a HOMO value -5.227 eV exhibits a nucleophilic characteristic, with a high propensity to be degraded by ozone and hydroxyl radical due to their lower HOMO-LUMO energy gaps of 4.99 and 4.22 eV respectively. …”
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    Predicting the degradation potential of Acid blue 113 by different oxidants using quantum chemical analysis
  17. 777
    “…The quantum properties were computed at the DFT(TPSSh-D3BJ/def2-SVP) level and include the electronic and dispersion energies, highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) energies, HOMO/LUMO gap, dipole moment, and natural charge of the metal center; GFN2-xTB polarizabilities are also provided. …”
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    tmQM Dataset—Quantum Geometries and Properties of 86k Transition Metal Complexes
  18. 778
    “…Patients with partial response (PR) or stable disease (SD) were classified into “PR homo,” “PR hetero,” “SD homo,” and “SD hetero” by the presence of a heterogeneous radiological response, and survival was compared between groups. …”
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    Heterogeneous radiological response to chemotherapy is associated with poor prognosis in advanced non‐small‐cell lung cancer
  19. 779
    “…We have found, first, that increasing the conjugation in the bidentate ligand reduces the highest occupied molecular orbital (HOMO)–lowest unoccupied molecular orbital (LUMO) energy gap of the complex, so its absorption wavelength red-shifts. …”
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    Computational Design of Rhenium(I) Carbonyl Complexes for Anticancer Photodynamic Therapy
  20. 780
    “…OBJECTIVES: During the middle‐to‐upper Paleolithic transition (50,000 and 40,000 years ago), interaction between Neanderthals and Homo sapiens varied across Europe. In southern Italy, the association between Homo sapiens fossils and non‐Mousterian material culture, as well as the mode and tempo of Neanderthal demise, are still vividly debated. …”
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    Direct evidence that late Neanderthal occupation precedes a technological shift in southwestern Italy
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