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1361por Tóth-Petróczy, Ágnes, Oldfield, Christopher J., Simon, István, Takagi, Yuichiro, Dunker, A. Keith, Uversky, Vladimir N., Fuxreiter, Monika“…Indeed, a high prevalence of IDRs was found in various subunits of Mediator from both Saccharomyces cerevisiae and Homo sapiens, especially in the Tail and the Middle modules. …”
Publicado 2008
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1362“…The study was done using the largest so far set of entries comprising 260 hetero and 2148 homo protein-protein complexes extracted from a previously developed database of protein complexes (ProtCom). …”
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1363por Zsurka, Gábor, Kudina, Tatiana, Peeva, Viktoriya, Hallmann, Kerstin, Elger, Christian E, Khrapko, Konstantin, Kunz, Wolfram S“…BACKGROUND: We have analyzed the complete mitochondrial genomes of 22 Pan paniscus (bonobo, pygmy chimpanzee) individuals to assess the detailed mitochondrial DNA (mtDNA) phylogeny of this close relative of Homo sapiens. RESULTS: We identified three major clades among bonobos that separated approximately 540,000 years ago, as suggested by Bayesian analysis. …”
Publicado 2010
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1364por George, Julie, Motshwene, Precious G., Wang, Hui, Kubarenko, Andriy V., Rautanen, Anna, Mills, Tara C., Hill, Adrian V. S., Gay, Nicholas J., Weber, Alexander N. R.“…Using S34Y and R98C as functional probes, our data show that MyD88 homo-oligomerization and IRAK4 interaction is modulated by the MyD88 TIR and IRAK4 kinase domain, demonstrating the functional importance of non-DD regions not observed in a recent Myddosome crystal structure. …”
Publicado 2011
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1365por O’Bleness, Majesta S., Dickens, C. Michael, Dumas, Laura J., Kehrer-Sawatzki, Hildegard, Wyckoff, Gerald J., Sikela, James M.“…Most importantly, we show that the exceptional HLS increase in DUF1220 copy number (from 102 in our last common ancestor with chimp to 272 in human; an average HLS increase of ∼28 copies every million years since the Homo/Pan split) was driven by intragenic domain hyperamplification. …”
Publicado 2012
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1366por Willadsen, Kai, Cao, Minh Duc, Wiles, Janet, Balasubramanian, Sureshkumar, Bodén, Mikael“…By distinguishing between homo-amino acid tracts that are encoded by tri-nucleotide repeats, and those encoded by varying codons, we show that amino acid repeats – not tri-nucleotide repeats – fully explain these regulatory associations. …”
Publicado 2013
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1367“…Co-activation of homo- and heterotopic representations in the primary motor cortex (M1) ipsilateral to a unilateral motor task has been observed in neuroimaging studies. …”
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1368por Marín-Padilla, Miguel“…The presence of six pyramidal cell functional strata distinguish the human motor cortex from that of others primates. Homo sapiens represent a new evolutionary stage that have transformed his primate brain for operating his unique motor capabilities, such as speaking, writing, painting, sculpturing and thinking as a premotor activity. …”
Publicado 2014
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1369por Benso, Alfredo, Di Carlo, Stefano, ur Rehman, Hafeez, Politano, Gianfranco, Savino, Alessandro, Suravajhala, Prashanth“…The predicted precision and accuracy is 100% for more than half of the input set for both species; overall, we obtained 85.38% precision and 81.95% accuracy for Homo sapiens and 79.73% precision and 80.06% accuracy for Saccharomyces Cerevisiae species proteins.…”
Publicado 2013
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1370por Yoon, Ju-An, Kim, You-Hyun, Kim, Nam Ho, Yoo, Seung Il, Lee, Sang Youn, Zhu, Fu Rong, Kim, Woo Young“…Conventional QWS blue OLEDs composed of multiple emissive layers and charge blocking layer with lower highest occupied molecular orbital (HOMO)-lowest unoccupied molecular orbital (LUMO) energy level, and devices with triple emissive layers for more significant hole-electron recombination and a wider region for exciton generation were designed. …”
Publicado 2014
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1371por Mandić, Maja, Drinovec, Luka, Glisic, Sanja, Veljkovic, Nevena, Nøhr, Jane, Vrecl, Milka“…Saturation assay data suggested constitutive β(2)AR and IR homo- and heteromerization. Calculated acceptor/donor (AD(50)) values as a measure of the relative affinity for homo- and heteromer formation differed among the heteromers that could not be explained by a simple dimer model. …”
Publicado 2014
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1372por Yu, Lu, Wang, Wei, Ling, Shenglong, Liu, Sanling, Xiao, Liang, Xin, Yanlong, Lai, Chaohua, Xiong, Ying, Zhang, Longhua, Tian, Changlin“…Moreover, integrin clustering occurs by homo-oligomeric interactions between the TM helices. …”
Publicado 2015
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1373por Kim, Nayoung K. D., Higashi, Tomohito, Lee, Kyoung Yeul, Kim, Ah Reum, Kitajiri, Shin-ichiro, Kim, Min Young, Chang, Mun Young, Kim, Veronica, Oh, Seung-Ha, Kim, Dongsup, Furuse, Mikio, Park, Woong-Yang, Choi, Byung Yoon“…Additionally, three-dimensional protein modeling revealed that angulin-2/ILDR1 contributed to tTJ by forming a homo-trimer structure through its Ig-like domain, and the p.P69H variant was predicted to disturb homo-trimer formation. …”
Publicado 2015
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1374“…Because Nup54 and Nup58 cognate segments form crystallographic hetero- or homo-oligomers, we proposed that these oligomers associate into inter-convertible “mid-plane” rings: a single large ring (40–50 nm diameter, consisting of eight hetero-dodecamers) or three small rings (10–20 nm diameter, each comprising eight homo-tetramers). …”
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1375por Inoguchi, Noriko, Chaiseeda, Kittichai, Yamanishi, Mamoru, Kim, Moon Ki, Jang, Yunho, Bajaj, Mamta, Chia, Catherine P., Becker, Donald F., Moriyama, Hideaki“…The structure of the homo-trimeric A. thaliana dUTPase showed three active sites, each with a different set of ligand interactions between the amino acids and water molecules. …”
Publicado 2015
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1376por Feng, Simin, dos Santos, Maria Cristina, Carvalho, Bruno R., Lv, Ruitao, Li, Qing, Fujisawa, Kazunori, Elías, Ana Laura, Lei, Yu, Perea-López, Nestor, Endo, Morinobu, Pan, Minghu, Pimenta, Marcos A., Terrones, Mauricio“…This work demonstrates that nitrogen-doped graphene has enormous potential as a substrate when detecting low concentrations of molecules and could also allow for an effective identification of their HOMO-LUMO gaps.…”
Publicado 2016
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1377por Been, Ella, Hovers, Erella, Ekshtain, Ravid, Malinski-Buller, Ariel, Agha, Nuha, Barash, Alon, Mayer, Daniella E. Bar-Yosef, Benazzi, Stefano, Hublin, Jean-Jacques, Levin, Lihi, Greenbaum, Noam, Mitki, Netta, Oxilia, Gregorio, Porat, Naomi, Roskin, Joel, Soudack, Michalle, Yeshurun, Reuven, Shahack-Gross, Ruth, Nir, Nadav, Stahlschmidt, Mareike C., Rak, Yoel, Barzilai, Omry“…The fossil record shows that two types of hominins occupied the region during this period—Neandertals and Homo sapiens. Until recently, diagnostic fossil remains were found only at cave sites. …”
Publicado 2017
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1378por Li, Zong-Liang, Yi, Xiao-Hua, Liu, Ran, Bi, Jun-Jie, Fu, Huan-Yan, Zhang, Guang-Ping, Song, Yu-Zhi, Wang, Chuan-Kui“…The numerical results show that the NDC behavior of TADHA molecular junction originates from the Stark effect of the applied bias which splits the degeneration of the highest occupied molecular orbital (HOMO) and HOMO-1. The H(2)O molecule adsorbed on the terminal sulphur atom strongly suppresses the conductance of TADHA molecular device and destroys the NDC behavior in the lower bias regime. …”
Publicado 2017
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1379“…In plants, cytosolic and plastidic enzymes share several characteristics such as NADP specificity (NADP-ME), oxaloacetate decarboxylase (OAD) activity, and homo-oligomeric assembly. However, mitochondrial counterparts are NAD-dependent proteins (mNAD-ME) lacking OAD activity, which can be structured as homo- and hetero-oligomers of two different subunits. …”
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1380por Zhang, Hao, Wu, Yongzhen, Zhang, Weiwei, Li, Erpeng, Shen, Chao, Jiang, Huiyun, Tian, He, Zhu, Wei-Hong“…However, incorporation of electron-rich cores can lead to undesirable up-shift in the HOMO energy level and low stability, and few of these new HTMs can outperform spiro-OMeTAD in terms of device efficiency. …”
Publicado 2018
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