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26441por Li, Xuemei, Hu, Jike, Gu, Baohong, Paul, Maswikiti Ewetse, Wang, Bofang, Yu, Yang, Feng, Zedong, Ma, Yanling, Wang, Xueyan, Chen, Hao“…MHCC97-H and PLC/PRF/5 cell lines can be used to successfully establish a model of HCC intrahepatic metastasis with distinctive characteristics, which provides an important direction for the study of the mechanism of HCC intrahepatic metastasis, and may hopefully provide a basis for clinical treatment.…”
Publicado 2020
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26442por Ristori, Maria Vittoria, Mortera, Stefano Levi, Marzano, Valeria, Guerrera, Silvia, Vernocchi, Pamela, Ianiro, Gianluca, Gardini, Simone, Torre, Giuliano, Valeri, Giovanni, Vicari, Stefano, Gasbarrini, Antonio, Putignani, Lorenza“…Moreover, the way to exploit CDSS, performed by artificial intelligence, is presented as an effective tool to integrate omics data to electronic health/medical records (EHR/EMR), hopefully acting as added value in the near future for the clinical management of ASD.…”
Publicado 2020
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26443por Szigyártó, Imola Cs., Mihály, Judith, Wacha, András, Bogdán, Dóra, Juhász, Tünde, Kohut, Gergely, Schlosser, Gitta, Zsila, Ferenc, Urlacher, Vlada, Varga, Zoltán, Fülöp, Ferenc, Bóta, Attila, Mándity, István, Beke-Somfai, Tamás“…For the tested, peptides the mixed chirality pattern resulted in similar assemblies despite sequential differences. Based on this, it is hoped that the presented molecular framework will inspire similar oligomers with diverse functionality.…”
Publicado 2020
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26444por Singh, Sheetu, Sharma, Bharat Bhushan, Bairwa, Mohan, Gothi, Dipti, Desai, Unnati, Joshi, Jyotsna M, Talwar, Deepak, Singh, Abhijeet, Dhar, Raja, Sharma, Ambika, Ahluwalia, Bineet, Mangal, Daya K, Jain, Nirmal K, Pilania, Khushboo, Hadda, Vijay, Koul, Parvaiz A, Luhadia, Shanti Kumar, Swarnkar, Rajesh, Gaur, Shailender Nath, Ghoshal, Aloke G, Nene, Amita, Jindal, Arpita, Jankharia, Bhavin, Ravindran, Chetambath, Choudhary, Dhruv, Behera, Digambar, Christopher, DJ, Khilnani, Gopi C, Samaria, Jai Kumar, Singh, Harpreet, Gupta, Krishna Bihari, Pilania, Manju, Gupta, Manohar L, Misra, Narayan, Singh, Nishtha, Gupta, Prahlad R, Chhajed, Prashant N., Kumar, Raj, Chawla, Rajesh, Jenaw, Rajendra K, Chawla, Rakesh, Guleria, Randeep, Agarwal, Ritesh, Narsimhan, R, Katiyar, Sandeep, Mehta, Sanjeev, Dhooria, Sahajal, Chowdhury, Sushmita R, Jindal, Surinder K, Katiyar, Subodh K, Chaudhri, Sudhir, Gupta, Neeraj, Singh, Sunita, Kant, Surya, Udwadia, Zarir F., Singh, Virendra, Raghu, Ganesh“…CONCLUSION: This document provides the guidelines made by consensus of opinions among experts following discussion of systematic review of evidence pertaining to the specific questions for management of ILD other than IPF. It is hoped that this document will help the clinician understand the accumulated evidence and help better management of idiopathic and nonidiopathic interstitial pneumonias.…”
Publicado 2020
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26445por Mustafayev, Revan, Seyid-Mammadova, Tarana, Kennedy, Colin R, Ertem, Ilgi Ozturk, Forsyth, Brian, Weber, Martin“…With increasing use of evidence-based medicine guidelines in the region, it is hoped that PE-SIH will gradually disappear, but actions to accelerate this change are nevertheless needed.…”
Publicado 2020
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26446por AbdelMassih, Antoine Fakhry, Fouda, Raghda, Kamel, Aya, Mishriky, Fady, Ismail, Habiba-Allah, El Qadi, Layla, Malak, Lauris, Mohamed, Maram, Arsanyous, Mariem, Hazem, Maysa, El-Husseiny, Miral, Ashraf, Mirette, Hafez, Nada, AlShehry, Nada, El-Husseiny, Nadine, AbdelRaouf, Nora, Shebl, Noura, Hafez, Nouran, Youssef, Nourhan, Afdal, Peter, Hozaien, Rafeef, Menshawey, Rahma, Saeed, Rana, Yasser, Reem, Hesham, Shereen, Zakarriah, Wesam, Khattab, Shahenda, Elammary, Yasmine, Ye, Jianping“…These findings demonstrate the necessity of single cell sequencing as a rapid means to identify and treat those who are most likely to need hospital admission and intensive care, in the hopes of precision medicine. Furthermore, this study underlines the use of immune modulators such as Leptin sensitizers, rather than immune suppressors as anti-inflammation therapies to switch the inflammatory response from a drastic immunological type 1 response to a beneficial type 2 effective one.…”
Publicado 2020
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26447“…Our treatment team was hopeful that ECT was making a difference for this patient. …”
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26448“…As Covid-19 spreads across the world, governments turn a hopeful eye towards research and development of a vaccine against this new disease. …”
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26449“…A therapeutic modality which provides all these mechanisms undoubtedly hold a strong potential to help COVID-19 patients even those with the worst condition to hopefully survive and recover.…”
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26450por Langer, Álvaro I., Medeiros, Sebastián, Valdés-Sánchez, Nelson, Brito, Rodrigo, Steinebach, Christoph, Cid-Parra, Cristian, Magni, Antonella, Krause, Mariane“…These effects are linked to self-regulation strategies, based on paying attention to one’s somatic experience with kindness and curiosity, which works as an attentional anchor. It is hoped that these results will contribute to the spread of mindfulness research in adolescents in Latin America, thus facilitating cross-cultural and international comparisons.…”
Publicado 2020
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26451por Chandran, M., Bhadada, S.K., Ebeling, P.R., Gilchrist, N.L., Khan, A.H., Halbout, P., Lekamwasam, S., Lyubomirsky, G., Mitchell, P.J., Nguyen, T.V., Tiu, K.L.“…The Framework will also facilitate benchmarking for provision of quality of care. It is hoped that the principles underlying the formation and functioning of APCO can be adopted by other regions and that every health care facility and progressively every country in the world can follow our aspirational path and progress towards best practice.…”
Publicado 2020
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26452por Chiba, Shuntaro, Tanabe, Aki, Nakakido, Makoto, Okuno, Yasushi, Tsumoto, Kouhei, Ohta, Masateru“…The double-point mutation approach using the interaction analysis of 3D structures expands the design repertoire for mutants, and hopefully paves a way for the identification of cooperative multiple-point mutations.…”
Publicado 2020
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26453“…As our understanding of tumor profile gains sophistication, a growing interest in targeted therapies and moreover the use of tumor profile to inform these therapies has developed in the hopes of altering nearly uniformly poor outcomes. …”
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26454“…Moreover, all four compounds formed conservative hydrogen bonds with the residues Asp164, Gln269, and Tyr273. We hoped that these four compounds might represent the promising chemical scaffolds for further development of novel PLpro inhibitors against COVID-19. …”
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26455“…Therefore, in this review, we exclusively update the context of plant-based metallic nanoparticle synthesis, characterization, and applications in detailed coverage. Hopefully, our review will be modernizing the recent trends going on in metallic nanoparticles synthesis for the blooming research fraternities. …”
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26456por Tomihara, Hideo, Hashimoto, Kazuhiko, Wakasa, Tomoko, Ishikawa, Hajime, Tsujimoto, Tomoyuki, Gakuhara, Atsushi, Fukuda, Shuichi, Ohta, Katsuya, Kitani, Kotaro, Hida, Jin-ichi, Ohta, Yoshio, Yukawa, Masao“…He had no right quadrant pain, fever, jaundice, weight loss, or carcinoid syndrome-related symptoms. The patient hoped to avoid cholecystectomy. During the 3-year observation period, the polyp gradually increased in size from 8.3 to 9.9 mm. …”
Publicado 2020
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26457“…Although these studies are still in the preclinical stages, it is hoped that safe, efficacious, and cost-effective interventions will be developed to save the host’s natural joint.…”
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26458por Che Man, Rohaina, Sulaiman, Nadiah, Ishak, Mohamad Fikeri, Bt Hj Idrus, Ruszymah, Abdul Rahman, Mohd Ramzisham, Yazid, Muhammad Dain“…However, there is no study utilising the combination of approaches that might give a better outcome in combating intimal hyperplasia. Hopefully, this concise review will provide an insight regarding the usage of different novel approaches in halting the progression of intimal hyperplasia, which serves as a key factor for the development of atherosclerosis in cardiovascular disease.…”
Publicado 2020
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26459por Flaive, Aurélie, Fougère, Maxime, van der Zouwen, Cornelis Immanuel, Ryczko, Dimitri“…This mini review may hopefully inspire future studies aiming at dissecting the complex effects of 5-HT on locomotor function.…”
Publicado 2020
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26460Problems with Early Systematic Reviews: The Case of Coronavirus Disease 2019 (COVID-19) in Pregnancypor Ang, Xue Ling, Chonkar, Sonali Prashant, Chua, Monica Shi Qi, Sulaiman, Suzanna, Lee, Jill Cheng Sim“…Hence, this evaluation hopes to highlight some of these problems and provide suggestions to help clinicians mitigate and make reasonable conclusions when reading the abundant yet limited body of evidence when furthering their research efforts. …”
Publicado 2020
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