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26781por Bitencourt, André L. B., Campos, Raquel M., Cline, Erika N., Klein, William L., Sebollela, Adriano“…We envision that advances in this field may lead to the development of novel oligomer-selective antibody fragments with superior selectivity and, hopefully, good clinical outcomes.…”
Publicado 2020
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26782“…This facilitated reconnection to their present and future hopes, which in turn increased their motivation to live and to adhere to treatment. …”
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26783por Boyero, Laura, Sánchez-Gastaldo, Amparo, Alonso, Miriam, Noguera-Uclés, José Francisco, Molina-Pinelo, Sonia, Bernabé-Caro, Reyes“…ABSTRACT: After several decades without maintained responses or long-term survival of patients with lung cancer, novel therapies have emerged as a hopeful milestone in this research field. The appearance of immunotherapy, especially immune checkpoint inhibitors, has improved both the overall survival and quality of life of patients, many of whom are diagnosed late when classical treatments are ineffective. …”
Publicado 2020
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26784por Nisiewicz, Monika K., Kowalczyk, Agata, Sobiepanek, Anna, Jagielska, Agata, Wagner, Barbara, Nowakowska, Julita, Gniadek, Marianna, Grudzinski, Ireneusz P., Kobiela, Tomasz, Nowicka, Anna M.“…Therefore, our data opens a new avenue for further studies in the short-term addressing novel targets that hopefully can be used to improve the therapeutic regiment in advanced melanoma patients. …”
Publicado 2021
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26785“…Finally, and on the basis of the findings obtained, possible guidelines are given, which, hopefully, may effectively contribute to the prevention of and/or intervention in compulsive buying among young adults.…”
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26786por Gilworth, Gill, Milton, Sarah, Chater, Angel, Nazareth, Irwin, Roposch, Andreas, Green, Judith“…They had few specific expectations of the check in terms of what examinations were undertaken, but even experienced parents anticipated reassurance about their baby’s normal development. Many also hoped for reassurance about their own parenting. …”
Publicado 2020
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26787por Suttorp, Meinolf, Millot, Frédéric, Sembill, Stephanie, Deutsch, Hélène, Metzler, Markus“…This article aims to; (i) define the disease based on the WHO nomenclature, the appropriate ICD 11 code and to unify the terminology, (ii) delineate features of epidemiology, etiology, and pathophysiology that are shared, but also differing between adult and pediatric patients with CML, (iii) give a short summary on the diseases to be considered as a differential diagnosis of pediatric CML, (iv) to describe the morphological, histopathological and immunophenotypical findings of CML in pediatric patients, (v) illustrate rare but classical complications resulting from rheological problems observed at diagnosis, (vi) list essential and desirable diagnostic criteria, which hopefully in the future will help to unify the attempts when approaching this rare pediatric malignancy.…”
Publicado 2021
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26788“…Several norovirus vaccines are currently undergoing clinical trials with promising results. It is hoped that development of an effective norovirus vaccine will further reduce the incidence of viral gastroenteritis.…”
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26789“…According to the simulation result, the specific relation between the optimal nitrogen injection point N(x) and the distance from the working distance of the cross-cut (x) by Newton interpolation polynomial analysis was figured out and verified that N(x) = 24.70808 + 0.293356x – 0.001436x(2). It is hoped that the result can provide scientific guidance for coal mine fire prevention and control with nitrogen injection.…”
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26790“…Our study found that prenatal morphine exposure in spiny mice led to an increase in withdrawal behavior throughout the early postnatal period and validated the use of this species as a novel pre-clinical model of NOWS. We are hopeful this rodent model will further our understanding of the short and long-term consequences of prenatal opioid exposure on neurodevelopment and behavior.…”
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26791“…This article mainly studies the effect of nursing intervention on preventing gastrointestinal surgical incision infection, and hopes to provide help for preventing gastrointestinal surgical incision infection. …”
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26792por Schulz, Joseph M.“…The following review focuses on the current uses of iPSC and how they have the potential to regenerate damaged neuronal tissue, in the hopes that these technologies can assist in getting through the bottleneck of AD therapeutic research.…”
Publicado 2021
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26793“…A larger portion of the Shaanxi province (70%) is found to be at a higher risk of erosion. Therefore, it is hoped that the findings from this research would further boost the integration of fractals into EPM in China and similar regions across the World. …”
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26794“…The circles explored youth knowledge, perceptions, questions, concerns, and hopes for cancer information; community members’ desires for youth knowledge about cancer; and how teachers would like content to be formatted for effective inclusion in their classrooms. …”
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26795“…The Chinese government has made great efforts to improve the scale efficiency of land through various measures during recent years, hoping to realize the coordinated developing goal of promoting agricultural benefits and protecting the environment. …”
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26796por Abdelghafour, Mohamed M., Orbán, Ágoston, Deák, Ágota, Lamch, Łukasz, Frank, Éva, Nagy, Roland, Ádám, Adél, Sipos, Pál, Farkas, Eszter, Bari, Ferenc, Janovák, László“…These measurements were also allowed to determine important parameters such as the coefficients A (=0.67) and B (=3.69 × 10(4)) from the Schulz equation, or the K(η) (=8.22 × 10(−2)) and α (=0.52) constants from the Kuhn–Mark–Houwink equation. Hopefully, the prepared PES with different molecular weights is a promising candidate for biomedical applications and the reported data and constants are useful for other researchers who work with this promising polyester.…”
Publicado 2021
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26797“…This algorithm attempts to weigh pros and cons regarding the benefit for an individual patient and hopefully assists caregivers to make better, informed decisions.…”
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26798“…The objective of this study was to explore the application value of intracavitary electrocardiogram- (IEGM-) guided diagnosis of occult heart disease and conventional electrocardiogram (EGM) in the diagnosis of occult coronary heart disease (CHD) based on the classification and regression tree (CART) mining algorithm, hoping to provide a more effective basis for clinical diagnosis of the occult CHD. …”
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26799“…The average evaluation accuracy of fuzzy clustering generalized regression neural network model is 98.44%, and the evaluation results of the model are better than other algorithms. It is hoped that this study can provide some reference value for the evaluation of teachers' educational technology ability in colleges and universities in China.…”
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26800“…Majority of the sampled migrants reported the problem of nervousness, anxiety, and depression; however, they were also hopeful about the future. The psychological problem was severe for the migrants above the age of 40, not educated, and with a higher number of family members. …”
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