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27641por Takamura, Kaori, Kobayashi, Hiroshi, Rubin, Brian P., Kondo, Shuhei, Asami, Fuyuki, Aoyagi, Ryuji, Ajioka, Yoichi“…Overall prognosis of aortic sarcoma is poor as most patients die within a year, with no effective treatments. It is hoped that recent projects for genomic medicine will provide useful insights about the diagnosis and treatment of these cancers.…”
Publicado 2021
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27642“…About 84.69% of students believed that their examinations should be postponed hoping to get appropriate clinical experience once things normalize. …”
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27643“…We conducted semi-structured phone interviews to elicit emotions, expectations and hopes in relation to the present situation, and the post-pandemic world. …”
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27644“…Therefore, there is a critical need for advancement of new anticancer drugs. Regarding the hopeful biological activity of phthalimide derivatives, in this study, synthesis, cytotoxicity, and pro-apoptosis activity of eleven derivatives of thiazole bearing phthalimide structure were evaluated. …”
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27645“…Based on the discoveries, we propose a rigorous procedure for developing SSP algorithms and making reliable evaluations, hoping to bring substantial improvements to future SSP methods and benefit all research and application fields relying on accurate prediction of protein secondary structures.…”
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27646“…This method will be useful in studying genes expressed in immature life stages of the mosquitoes and will hopefully open new avenues for identifying mosquito control targets in early life stages. …”
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27647por Shi, Xueying, Xia, Shilin, Chu, Yingming, Yang, Nan, Zheng, Jingyuan, Chen, Qianyi, Fen, Zeng, Jiang, Yuankuan, Fang, Shifeng, Lin, Jingrong“…Our study analyzed prognostic value and immune-related characteristics of CARD11 in UVM, hoping to provide a potential management and research direction. …”
Publicado 2021
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27648“…We share these results here with the goal of helping the community combat the common challenges associated with anti-BRCA1 antibody specificity and reproducibility and, hopefully, better understanding BRCA1 functions at cellular and tissue levels.…”
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27649por Kuo, Hui-Ying, Hsiao, John Ching-Jen, Chen, Jing-Jie, Lee, Chi-Hung, Chuang, Chun-Chao, Sun, Han-Yin“…This could be the first study investigating the relationship between peripheral refraction and ocular dimension in high myopes, and it is hoped to provide useful knowledge of how the development of myopia changes human eye shape.…”
Publicado 2021
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27650por Ganadu, Maria Luisa, Demartin, Francesco, Panzanelli, Angelo, Zangrando, Ennio, Peana, Massimiliano, Medici, Serenella, Zoroddu, Maria Antonietta“…The present work opens with an acknowledgement to the research activity performed by Luciana Naldini while affiliated at the Università degli Studi di Sassari (Italy), in particular towards gold complexes and clusters, as a tribute to her outstanding figure in a time and a society where being a woman in science was rather difficult, hoping her achievements could be of inspiration to young female chemists in pursuing their careers against the many hurdles they may encounter. …”
Publicado 2021
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27651por Qian, Xi‐Feng, Duan, Ai‐Ling, Huang, Rong‐Xian, Li, Nan‐Xi, Li, Ya‐Ping, Guo, Xu‐Guang“…However, further extension of this approach should be researched to ensure the accuracy and practicability of this hopeful test in the future.…”
Publicado 2021
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27652por Gholamzad, Mehrdad, Baharlooi, Hussein, Shafiee Ardestani, Mehdi, Seyedkhan, Zeinab, Azimi, Maryam“…The MOG-PGLA particles are potentially valuable for further evaluations, hopefully progressing toward an optimal approach that can be translated to the clinic.…”
Publicado 2021
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27653por Scheer, Volker, Tiller, Nicholas B., Doutreleau, Stéphane, Khodaee, Morteza, Knechtle, Beat, Pasternak, Andrew, Rojas-Valverde, Daniel“…Indeed, failure to consider sex differences in the design of female-specific UER training programs may have a negative impact on athlete longevity. It is hoped that this review will inform risk stratification and stimulate further research about UER and the implications for long-term health.…”
Publicado 2021
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27654por Rafael-Patino, Jonathan, Girard, Gabriel, Truffet, Raphaël, Pizzolato, Marco, Caruyer, Emmanuel, Thiran, Jean-Philippe“…The methodological development in the mapping of the brain structural connectome from diffusion-weighted magnetic resonance imaging (DW-MRI) has raised many hopes in the neuroscientific community. Indeed, the knowledge of the connections between different brain regions is fundamental to study brain anatomy and function. …”
Publicado 2021
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27655“…CONCLUSION: The DTSaM orthosis produces a motion similar to the DTM. It is hoped that the use of the DTSaM orthosis will help to shorten the treatment period for patients with wrist disease.…”
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27656por Michelakou, Eleni, Giaouris, Efstathios, Doultsos, Dimitrios, Nasopoulou, Constantina, Skandamis, Panagiotis“…Although salt replacers could have been used to improve its flavor and at the same time increase its shelf life, the product here developed without the use of such alternatives will hopefully contribute to the taste training of its consumers for less salt in their diet, keeping in parallel its clean label with no added preservatives and other food additives.…”
Publicado 2021
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27657“…Purpose: The purpose was to get a deeper understanding of the underlying reasons why additional monitoring has not increased AE reporting as much as initially hoped. We examined how healthcare professionals (HCPs) in Finland perceive additional monitoring, why they do or do not report AEs more readily for these medicines and how they interact with patients treated with additionally monitored medicines. …”
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27658
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27659“…SIMPLE SUMMARY: The clinical success of cancer immunotherapy targeting immune checkpoints (e.g., PD-1, CTLA-4) has ushered in a new era of cancer therapeutics aimed at promoting antitumor immunity in hopes of offering durable clinical responses for patients with advanced, metastatic cancer. …”
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27660“…The objective of this review was to explore the relationship between lifestyle, anthropometric, and genetic factors and cardiometabolic risk factors. We are hopeful that our findings may aid in the primary prevention of hypertension in children and the prevention of any related cardiovascular complications that may arise later in life as a result of obesity. …”
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