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  1. 27781
    “…Many healthcare resources cannot be attributed to individual patients so the very notion of “patient-level” costs may be misplaced. High hopes have been put in these new data, though much more work is now necessary to understand their quality, what they show and how their use will impact the system.…”
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    NHS reference costs: a history and cautionary note
  2. 27782
    “…CONCLUSION: The current version of DSRC was shown to have excellent overall usability properties in handling research regulatory issues. It is hoped that its release as an open-source application will promote improved and streamlined regulatory processes for individual academic centers as well as larger research networks.…”
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    Duke Surgery Research Central: an open-source Web application for the improvement of compliance with research regulation
  3. 27783
    “…BACKGROUND: It is often felt that developing countries need to improve their quality of healthcare provision. This study hopes to generate data that can help managers and doctors to improve the standard of care they provide in line with the wishes of the patients. …”
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    Patients' satisfaction and opinions of their experiences during admission in a tertiary care hospital in Pakistan – a cross sectional study
  4. 27784
    “…The evaluation of the molecular background of carcinogenesis hopefully is capable of providing more sensitive diagnostic markers. …”
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    Methylation status of p14ARF and p16INK4a as detected in pancreatic secretions
  5. 27785
    “…The primary measure is level of faecal butyrate, which it is hoped will be elevated by moving subjects to a high fibre diet. …”
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    A study protocol to investigate the relationship between dietary fibre intake and fermentation, colon cell turnover, global protein acetylation and early carcinogenesis: the FACT study
  6. 27786
    “…This is part of our effort to couple known moieties that offer antitumor activity with biologically active units hoping to increase the biological activity of the combination. …”
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    Ability of Group IVB metallocene polyethers containing dienestrol to arrest the growth of selected cancer cell lines
  7. 27787
    “…This shortcoming is hopefully bound to disappear in the near future, thanks to the wealth of new genomic resources that are currently being developed for many species. …”
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    Candidate genes revealed by a genome scan for mosquito resistance to a bacterial insecticide: sequence and gene expression variations
  8. 27788
    “…There are successful disease control programmes in place within the country and it is hoped a healthy skin programme could be integrated into an established disease control programme in order to maximise health benefits and resources.…”
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    The prevalence of common skin infections in four districts in Timor-Leste: a cross sectional survey
  9. 27789
    “…DISCUSSION: This study protocol describes a pragmatic randomised controlled trial which it is hoped will address the above uncertainties. Three-year results will be available towards the end of 2010. …”
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    The SINS trial: A randomised controlled trial of excisional surgery versus imiquimod 5% cream for nodular and superficial basal cell carcinoma
  10. 27790
    “…Vaccines that can target such high risk groups in the country and the region will hopefully be able to reduce the disease morbidity and the transmission of pathogens that impact the life and health of people.…”
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    Impact of Rapid Urbanization on the Rates of Infection by Vibrio cholerae O1 and Enterotoxigenic Escherichia coli in Dhaka, Bangladesh
  11. 27791
    “…CONCLUSION: A hybrid in-silico and wet laboratory approach of motif prediction, evolutionary and structural analysis has pointed out serine 266 and 267 of the HCV E2 gene as a hopeful claimant for the serine phosphorylation. Recognition of these nucleotide variations may assist to propose genotype precise therapy to avoid and resolve HCV infections.…”
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    Positional effect of phosphorylation sites 266 and 267 in the cytoplasmic domain of the E2 protein of hepatitis C virus 3a genotype: Interferon Resistance analysis via Sequence Alignment
  12. 27792
    “…We propose a larger, multicentre study to explore and hopefully confirm this exciting, potentially important finding (NHMRC project grant number 627178). …”
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    The effect of testosterone and a nutritional supplement on hospital admissions in under-nourished, older people
  13. 27793
    “…CONCLUSION: These educational materials are all freely available http://www.narp.ca and will hopefully aid in increasing awareness of the importance of proper antimicrobial usage and hygiene in diminishing the spread of S. aureus and other infectious diseases in other communities.…”
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    Community-based educational intervention to limit the dissemination of community-associated methicillin-resistant Staphylococcus aureus in Northern Saskatchewan, Canada
  14. 27794
    “…CONCLUSION: Clearly, this type of rotation flap reconstruction is an oncologically safe and a cosmetically sound procedure. Hopefully this rotation flap reconstruction technique will become more widely available and perhaps a standard procedure for lower quadrant breast tumors, especially for cosmetic treatment of small to medium-sized breasts.…”
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    Oncoplastic Reconstruction with Superior Based Lateral Breast Rotation Flap after Lower Quadrant Tumor Resection
  15. 27795
    “…The proposed trial will contribute to the discussion and hopefully also to a decrease in the variability of clinical practice. …”
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    Design of COSMIC: a randomized, multi-centre controlled trial comparing conservative or early surgical management of incomplete cervical cord syndrome without spinal instability
  16. 27796
    “…The need for CPC is not going to go away and it is therefore important that models of scaling-up are found that are not only practical, feasible, affordable and sustainable, but that focus on the outcome of improved CPC for all those who need it. It is hoped that the lessons shared from the Beacon Project will help in developing and implementing such models.…”
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    Developing children’s palliative care in Africa through beacon centres: lessons learnt
  17. 27797
    “…The guidelines provide guidance for tertiary institutions to assist them in supporting students with a mental illness. It is hoped that they may be used to inform policy and practice in tertiary institutions.…”
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    Development of guidelines for tertiary education institutions to assist them in supporting students with a mental illness: a Delphi consensus study with Australian professionals and consumers
  18. 27798
    “…DISCUSSION: This trial will hopefully indicate the efficacy of group-based CBT for adults with high- functioning ASD. …”
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    A cognitive-behavioral intervention for emotion regulation in adults with high-functioning autism spectrum disorders: study protocol for a randomized controlled trial
  19. 27799
    “…Recent recommendations by the Bone Marker Standards Working Group propose to standardise research and include a specific marker of bone resorption (CTX) and bone formation (P1NP) in all future studies. It is hoped that improved research in turn will lead to optimised markers for the clinical management of osteoporosis and other bone diseases.…”
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    The clinical utility of bone marker measurements in osteoporosis
  20. 27800
    “…When epigenetic agents are used in combination with chemotherapy or targeted therapy it is hoped that downstream biological effects will provoke synergistic cytotoxicity. …”
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    Targeting the Epigenome in Lung Cancer: Expanding Approaches to Epigenetic Therapy
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