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  1. 27821
    “…The diverse treatment approach presented in this study might have resulted in a worse outcome than expected. Hopefully, unnecessary exposure to immunosuppressive therapy or delayed treatment can be avoided through better support, education and treatment forums, and thus result in an improved outcome.…”
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    Treatment pattern in patients with idiopathic membranous nephropathy—practices in Sweden at the start of the millennium
  2. 27822
    “…Increased scientific attention is hoped, particularly focused on addressing a better definition of diagnostic criteria, whose correctness and accuracy are critical, especially in situations with medicolegal implications.…”
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    Demographic variables, clinical aspects, and medicolegal implications in a population of patients with adjustment disorder
  3. 27823
    “…The ease of testing will hopefully encourage adoption and clinical validation.…”
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    Identification of BRCA1 Deficiency Using Multi-Analyte Estimation of BRCA1 and Its Repressors in FFPE Tumor Samples from Patients with Triple Negative Breast Cancer
  4. 27824
    “…These sequence resources hopefully will provide an opportunity for identifying genes involved in plant defense and several important quality traits in wild Nicotiana and will accelerate functional genomic studies and genetic improvement efforts of Nicotiana or other important Solanaceae crops in the future. …”
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    Sequencing and characterization of leaf transcriptomes of six diploid Nicotiana species
  5. 27825
    “…The policy aimed at improving hospitals’ performance, hoping to reduce government’s costs. However, the policy was never implemented as intended. …”
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    Fail to prepare and you can prepare to fail: the experience of financing path changes in teaching hospitals in Iran
  6. 27826
    por Rutishauser, Rolf
    Publicado 2016
    “…Some of them emerged as morphological key innovations (perhaps ‘hopeful monsters’) that gave rise to new evolutionary lines of organisms, based on (major) genetic changes. …”
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    Evolution of unusual morphologies in Lentibulariaceae (bladderworts and allies) and Podostemaceae (river-weeds): a pictorial report at the interface of developmental biology and morphological diversification
  7. 27827
    por Sørensen, Henrik Toft
    Publicado 2016
    “…A PhD program has two overall objectives: to extend knowledge about a hopefully important health topic and to provide extensive training to improve the PhD student’s skills through learning research methods and collaboration. …”
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    I-determinants for a successful PhD or postdoctoral outcome
  8. 27828
    “…CONCLUSIONS: The appropriate use of probiotics deserves further research, which hopefully will open new avenues in the fight against ASD.…”
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    Unexpected improvement in core autism spectrum disorder symptoms after long-term treatment with probiotics
  9. 27829
    “…Secondary outcomes will include time to relapse. DISCUSSION: It is hoped that the results from this study will help to clarify the mechanisms behind any beneficial changes due to family psychoeducation and provide information on the long-term effect of this intervention for both patient and relatives. …”
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    Family psychoeducation for major depressive disorder – study protocol for a randomized controlled trial
  10. 27830
    “…The study demonstrates high spatial accuracy of postmortem probabilistic tractography of the DRTT when compared to a 3D histological reconstruction. This gives hopeful prospect for studying structure–function correlations in patients with cerebellar disorders using tractography of the DRTT. …”
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    Dentatorubrothalamic tract localization with postmortem MR diffusion tractography compared to histological 3D reconstruction
  11. 27831
    “…FOCUS will possess adequate power to provide answers to relevant remaining questions regarding the patients’ long-term morbidity and mortality, and the temporal pattern of post-PE abnormalities. It will hopefully provide evidence for future guideline recommendations regarding the selection of patients for long-term follow-up after PE, the modalities which this follow-up should include, and the findings that should be interpreted as indicating progressive functional and hemodynamic post-PE impairment, or the development of CTEPH. …”
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    Late outcomes after acute pulmonary embolism: rationale and design of FOCUS, a prospective observational multicenter cohort study
  12. 27832
    “…We have also raised many unexplored but expected fundamental questions regarding CHIP functions, which generate hopes for its future applications in research, as well as drug discovery.…”
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    A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?
  13. 27833
    por Chalk, Stuart J.
    Publicado 2016
    “…CONCLUSION: The combination of a scripting environment (PHPStorm), a PHP Framework (CakePHP), a relational database (MySQL) and a code repository (GitHub) provides all the capabilities to easily develop REST based websites for ingestion, curation and exposure of open chemical data to the community at all levels. It is hoped this software stack (or equivalent ones in other scripting languages) will be leveraged to make more chemical data available for both humans and computers.…”
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    The Open Spectral Database: an open platform for sharing and searching spectral data
  14. 27834
    “…Despite the widespread recommendations to medical practitioners to check patients’ understanding directly, it does not appear to be routine practice. CONCLUSION: It is hoped that this research encourages more detailed examination of shared and divergent experiences of pain consultations and also their influence on the subsequent course of intervention and adherence to treatment (not addressed here).…”
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    Are patients’ and doctors’ accounts of the first specialist consultation for chronic back pain in agreement?
  15. 27835
    “…Therefore, we constructed a lentiviral vector expressing tyrosinase (TYR) driven by an optimized human telomerase reverse transcriptase (hTERT) promoter or a cytomegalovirus(CMV) promoter in the hopes of performing noninvasive and real-time tumor-specific imaging. …”
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    MR molecular imaging of tumors based on an optimal hTERT promoter tyrosinase expression system
  16. 27836
    “…Specifically, bringing different services together (service aggregation), it is hoped that the approach proposed will significantly increase the impact of information and communication technologies on access and adherence to treatment, quality of the service, patient safety, patient and professional satisfaction, and quality of life of patients. …”
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    Online psycho-education to the treatment of bipolar disorder: protocol of a randomized controlled trial
  17. 27837
    “…It is dedicated to the proteomic study of histones in mouse and human and will hopefully facilitate the identification and functional study of histone variants. …”
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    MS_HistoneDB, a manually curated resource for proteomic analysis of human and mouse histones
  18. 27838
    “…CONCLUSIONS: The extension of miRNAFold by the introduction of machine learning techniques, significantly increases selectivity in pre-miRNA ab initio prediction, which optimally contributes to advanced studies on miRNAs, as the need of biological validations is diminished. Hopefully, new research, such as studies of severe diseases caused by miRNA malfunction, will benefit from the proposed computational tool.…”
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    Mirnacle: machine learning with SMOTE and random forest for improving selectivity in pre-miRNA ab initio prediction
  19. 27839
    “…When replacing teeth by oral implants, one hopes to restore the sensory feedback pathway as such to allow for physiological implant integration and optimized oral function with implant-supported prostheses. …”
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    Short-term follow-up of masticatory adaptation after rehabilitation with an immediately loaded implant-supported prosthesis: a pilot assessment
  20. 27840
    “…This overview of current literature will hopefully provide the foundation for future standardization of clinical practice. …”
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    The diagnosis and management of the Spitz nevus in the pediatric population: a systematic review and meta-analysis protocol
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