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28521“…The patients with a painDETECT score ≥ 19 showed increased signs of anxiety (p < 0.05), depression (p < 0.01), praying and hoping (p < 0.05). CONCLUSION: The present study has shown that the PainDETECT questionnaire can be a helpful additional diagnostic tool. …”
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28522por de Fonseka, Duneesha, Morley, Anna, Stadon, Louise, Keenan, Emma, Walker, Steven, Smith, Sarah, Harvey, John E., Cox, R. Ashley, Dangoor, Adam, Comins, Charles, Rogers, Christine, Edey, Anthony, Addeo, Alfredo, Maskell, Nick A.“…DISCUSSION: The qualitative and quantitative data gathered in this feasibility trial will hopefully pave the way to designing a robust full phase III trial to investigate the potential synergistic effect of ZA and current standard treatment for MPM, cisplatin-pemetrexed combination chemotherapy. …”
Publicado 2018
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28523“…Early metastatic spread of cervical cancer cells may thus be controlled in the draining lymph node basin, and beyond, and hopefully delay or even prevent the onset of disease recurrence. …”
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28524por McGrath, Sophie Elena, Annels, Nicola, Madhuri, Thumuluru K., Tailor, Anil, Butler-Manuel, Simon A., Morgan, Richard, Pandha, Hardev, Michael, Agnieszka“…It demonstrates prognostic value, correlating with worse Overall Survival and Progression-free Survival. It is hoped that further work will validate its use as a biomarker, and provide insight into the role of EN2 in the development, progression and spread of ovarian cancer.…”
Publicado 2018
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28525por Holtz, Bree E, Mitchell, Katharine M, Hershey, Denise D, Cotten, Shelia R, Holmstrom, Amanda J, Richman, Joshua, Dunneback, Julie K, Wood, Michael A“…CONCLUSIONS: Adolescents with T1DM and their parents can have a difficult time managing the transition of diabetes care. It is hoped that this app can help. The focus groups and prototype testing have indicated promising outcomes of app use. …”
Publicado 2018
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28526“…DISCUSSION: Health warnings, such as those implemented by the TPD, may help to prevent non-smokers from e-cigarettes use, but it is possible that they may inadvertently deter smokers from initiating use and substituting their tobacco smoking for e-cigarettes use if their content is deemed too negative. It is hoped that this study will help identify the most effective message or combination of messages that encourage use among smokers without promoting use among non-smokers. …”
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28527por Claydon, Elizabeth A., Davidov, Danielle M., Zullig, Keith J., Lilly, Christa L., Cottrell, Lesley, Zerwas, Stephanie C.“…One theme, Battle between Mothering & Eating Disorder also had three sub-themes: Decision to Have Child, Emotions Towards Pregnancy, and Focus on Child/Greater Good. CONCLUSIONS: It is hoped that quotes and themes derived from this study will help inform both prenatal and postnatal care and interventions, as well as addressing intergenerational transmission concerns among mothers with eating disorders. …”
Publicado 2018
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28528por Shorey, Shefaly, Ng, Yvonne Peng Mei, Siew, An Ling, Yoong, Joanne, Mörelius, Evalotte“…CONCLUSIONS: This study will identify a potentially clinically useful, effective, and cost-effective supportive educational parenting program to improve parental self-efficacy and bonding in newborn care, which will then improve parents’ social support–seeking behaviors, emotional well-being, and satisfaction with parenting. It is hoped that better supported and satisfied parents will consider having more children, which may in turn influence Singapore’s ailing birth rate. …”
Publicado 2018
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28529por Duane, Sinead, Vellinga, Akke, Murphy, Andrew W., Cormican, Martin, Smyth, Andrew, Healy, Patricia, Moore, Michael, Little, Paul, Devane, Declan“…Phase 3 is a consensus meeting to finalise the COS that should be reported in trials evaluating the effectiveness of interventions for the treatment of UTI. DISCUSSION: It is hoped that the development of a COS for interventions for the treatment of uncomplicated UTI in adults will be adopted as a minimum set of outcomes that should be reported and measured within this context. …”
Publicado 2019
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28530por Jia, Yanfei, Gu, Dongsheng, Wan, Jun, Yu, Beiqin, Zhang, Xiaoli, Chiorean, E. Gabriela, Wang, Yunshan, Xie, Jingwu“…Thus far, numerous attempts using novel targeted therapies and immunotherapies yielded limited clinical benefits for pancreatic cancer patients. It is hoped that delineating the molecular mechanisms underlying drug resistance in pancreatic cancer may provide novel therapeutic options. …”
Publicado 2018
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28531por Scherz, Mark D., Hutter, Carl R., Rakotoarison, Andolalao, Riemann, Jana C., Rödel, Mark-Oliver, Ndriantsoa, Serge H., Glos, Julian, Hyde Roberts, Sam, Crottini, Angelica, Vences, Miguel, Glaw, Frank“…The evolution of body size in Madagascar’s microhylids has been more dynamic than previously understood, and future studies will hopefully shed light on the interplay between ecology and evolution of these remarkably diverse frogs.…”
Publicado 2019
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28532“…CONCLUSION: Based on the resistance-related lncRNAs, miRNAs, and mRNAs, we proposed the post-transcriptional regulation pathway to explain how camels respond to salt and water-deprivation stresses in the ncRNAs regulation level of renal cortex for the first time, thus hoping to provide a theoretical basis for therapy of disease that is similar to high blood pressure in humans. …”
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28533por Szász, József Attila, Orbán-Kis, Károly, Constantin, Viorelia Adelina, Péter, Csongor, Bíró, István, Mihály, István, Szegedi, Kinga, Balla, Antal, Szatmári, Szabolcs“…In younger patients and/or patients with mild symptoms we hoped to delay the motor complications by postponing the start of levodopa therapy. …”
Publicado 2019
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28534Gut microbiome differences between wild and captive black rhinoceros – implications for rhino healthpor Gibson, Keylie M., Nguyen, Bryan N., Neumann, Laura M., Miller, Michele, Buss, Peter, Daniels, Savel, Ahn, Michelle J., Crandall, Keith A., Pukazhenthi, Budhan“…Given the differences observed between wild and captive rhino gut microbiomes, we make a number of recommendations for potentially modifying captive gut microbiome to better reflect their wild counterparts and thereby hopefully improve overall rhino health in captivity.…”
Publicado 2019
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28535por Ozeki-Hayashi, Reina, Fujita, Misao, Tsuchiya, Atsushi, Hatta, Taichi, Nakazawa, Eisuke, Takimoto, Yoshiyuki, Akabayashi, Akira“…They proposed treatments as long as options remained, and when they ultimately judged that the physical condition of patients could not withstand further treatment, treatment was terminated despite the patient hoping for continuation. The other was a “belief that the patient is an entity who can accept death.” …”
Publicado 2019
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28536por Chen, Jihang, Leong, Pou Kuan, Leung, Hoi Yan, Chan, Wing Man, Li, Zhonggui, Qiu, Jingyu, Ko, Kam Ming, Chen, Jianping“…Taken together, these experimental results will hopefully provide insight into the pharmacological basis for the beneficial effects of XEASD in children suffering from TS.…”
Publicado 2019
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28537“…INTRODUCTION: Personal recovery has been defined as ‘a profound personal and unique process for the individual to change their attitudes, values, feelings, goals, abilities and roles in order to achieve a satisfactory, hopeful and productive way of life, with the possible limitations of the illness’. …”
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28538por Torrens, Gabriel, Escobar-Salom, María, Pol-Pol, Elisabet, Camps-Munar, Cristina, Cabot, Gabriel, López-Causapé, Carla, Rojo-Molinero, Estrella, Oliver, Antonio, Juan, Carlos“…Altogether, this work is a major step ahead to understand the biology of peptidoglycan from P. aeruginosa natural strains, hopefully useful in future for therapeutic alternatives design.…”
Publicado 2019
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28539por da Silva, Camila Oliveira, Dias, André Alves, da Costa Nery, José Augusto, de Miranda Machado, Alice, Ferreira, Helen, Rodrigues, Thais Fernanda, Sousa Santos, João Pedro, Nadaes, Natalia Rocha, Sarno, Euzenir Nunes, Saraiva, Elvira Maria, Schmitz, Verônica, Pessolani, Maria Cristina Vidal“…Altogether, our findings shed light on the pathogenesis of T2R, which, it is hoped, will contribute to the emergence of novel alternative therapies and the identification of prognostic reactional markers in the near future.…”
Publicado 2019
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28540por Proesmans, Sam, Katshongo, Freddy, Milambu, John, Fungula, Blaise, Muhindo Mavoko, Hypolite, Ahuka-Mundeke, Steve, Inocêncio da Luz, Raquel, Van Esbroeck, Marjan, Ariën, Kevin K., Cnops, Lieselotte, De Smet, Birgit, Lutumba, Pascal, Van geertruyden, Jean-Pierre, Vanlerberghe, Veerle“…This will not only stem the ever-increasing problem of antimicrobial resistance, but will–ultimately and hopefully–improve the clinical care of outpatients in low-resource settings. …”
Publicado 2019
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