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29041por Steininger, Julian, Gellrich, Frank Friedrich, Schulz, Alexander, Westphal, Dana, Beissert, Stefan, Meier, Friedegund“…Several studies focus particularly on poor prognosis patients, as e.g., on anti-PD-1 refractory melanoma, patients with brain metastases, or uveal melanoma. It is hoped, on the road to cure, that these new approaches further improve long term survival in patients with advanced or metastatic melanoma.…”
Publicado 2021
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29042“…The significance of our research is in identifying microenvironmental factors, such as commensal and pathogenic microbes, that can contribute to the establishment and maintenance of latent HIV-1 infection in macrophages. It is hoped that identifying key processes contributing to HIV-1 persistence in macrophages may ultimately lead to novel therapeutics to eliminate latent HIV-1 reservoirs in vivo.…”
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29043“…It is former to estimate that nearly 2.5 million tons of pesticides are utilized in agricultural production yearly and the global injury evoked by pesticides achieves $100 billion yearly. It is therefore hoped that natural oils can offer alternative options to synthesis acaricides and contribute to pesticide resistance. …”
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29044por Spencer, Corey C., Pflederer, Jeremiah A., Wilson, Jacob M., Dawes, Alexander M., Gottschalk, Michael B., Wagner, Eric R.“…This study also identified several independent risk factors for prolonged opioid use, including younger age, depression, and tobacco use. This study will hopefully help recognize high-risk patient populations and serve as the foundation for future studies into opioid prescription standardization and preoperative opioid education.…”
Publicado 2021
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29045por Beaudoin, Alisha, Larrivée, Samuel, McRae, Sheila, Leiter, Jeff, Stranges, Gregory“…CLINICAL RELEVANCE: Module-based simulation training provides additional training time and improves technical skills in naive health science students. It is hoped that this effect can be preserved and applied to junior resident developing in a busy residency program.…”
Publicado 2021
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29046por Kohut, Gergely, Juhász, Tünde, Quemé-Peña, Mayra, Bősze, Szilvia Erika, Beke-Somfai, Tamás“…The phenomenon observed here at a molecular level can be followed in several experimental systems studied recently, where peptides interact with food colors, drug molecules, or endogenous compounds, which strongly indicates that reversible associate formation is a general phenomenon for these complexes. These results are hoped to be exploited in novel therapeutic strategies aiming to use peptides as drug targets and control AMP bioactivity by directed assembly formation.…”
Publicado 2021
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29047por Zhao, Yalin, Li, Meihua, Yang, Yanxia, Wu, Tao, Huang, Qingyuan, Wu, Qinghua, Ren, Chaofeng“…At the same time, it is hoped that in-depth functional mining can provide new ideas for exploring the COPD pathogenesis.…”
Publicado 2021
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29048por Zhu, Bin, Hu, Lijuan, Qian, Fang, Gao, Zuomin, Gan, Chenchen, Liu, Zhaochao, Du, Xuye, Wang, Hongcheng“…These results will open the way for further studies on the evolutionary process from C3 to C4 photosynthesis and hopefully provide guidance for utilizing M. arvensis as a resource for improvinng photosynthesis efficiency in cultivated Brassica species.…”
Publicado 2021
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29049“…Improved knowledge of this disorder would help address the current lack of health and social care, hopefully preventing this shortfall's impact on social and affective relationships, which are particulary important for well-being now and in the coming periods of physical distancing measures.…”
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29050“…The results also showed that delayed mating was an effective measure to consider in controlling H. vigintioctopunctata. It is hoped that our data will provide a scientific basis and contribute technical guidance for forecasting and integrated management of this pest.…”
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29051por Etti, Melanie, Alger, Jackeline, Salas, Sofía P., Saggers, Robin, Ramdin, Tanusha, Endler, Margit, Gemzell-Danielsson, Kristina, Alfvén, Tobias, Ahmed, Yusuf, Callejas, Allison, Eskenazi, Deborah, Khalil, Asma, Le Doare, Kirsty“…This prioritized list of research uncertainties, developed to specifically highlight the most urgent clinical needs as perceived by healthcare professionals and researchers, could help funding organizations and researchers to answer the most pressing questions for clinicians and public health professionals during the pandemic. It is hoped that these identified priority research themes can help focus the discussion regarding the allocation of limited resources to enhance COVID-19 research in MNCH globally.…”
Publicado 2021
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29052por Han, Youming, Sui, Zhilin, Jia, Yongsheng, Wang, Hailong, Dong, Yan, Zhang, Hongdian, Li, Zhigang, Yu, Zhentao“…Conclusion: Patients aged ≥ 80 years were less likely to be receptive to cancer-related therapy and had the highest cancer mortality rate among all patients. Our findings will hopefully help clinicians develop more appropriate modalities of cancer treatment in elderly BC patients.…”
Publicado 2021
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29053“…This is a great example of how we integrate two current available technologies, next-generation sequencing and cloud computing, in practice into an applicable workflow for pandemics to tackle the issue of obtaining satisfactory results in a shorter time, while the abundant samples are available. Hopefully, the methods used in this study will intrigue more healthcare professionals to implement the cloud workflow as a part of the current identification method during the current or future pandemic and other infectious diseases as well. …”
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29054“…We particularly focus on zero anaphora resolution in the present study to try to discover some specific aspects of the underlying mechanism, hoping to find out some factors unique to the resolution process. …”
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29055por Kulesza, Wojciech, Dolinski, Dariusz, Muniak, Paweł, Derakhshan, Ali, Rizulla, Aidana, Banach, Maciej“…INTRODUCTION: Optimism is boosted by leaders hoping for job creation, increased business spending, and a high consumption rate. …”
Publicado 2020
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29056“…As vaccination campaigns are in progress in most countries, hopes to win back more normality are rising. However, the exact path from a pandemic to an endemic virus remains uncertain. …”
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29057por Stadler Elmer, Stefanie“…Songs mirror each generations’ wishes, desires, values, hopes, humor, and stories and rest on unfathomable traditions of our cultural and human history. …”
Publicado 2021
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29058“…In approximately one third of patients, we found new molecular alterations not present at the diagnostic biopsy, strengthening the relevance of performing a re-biopsy at progression to increase targeted treatment options, and hopefully bettering the prognosis. ABSTRACT: Background: Genomic profiling in advanced Non-Small Cell Lung cancer (NSCLC) can reveal Actionable Molecular Alterations (AMAs). …”
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29059“…CONCLUSION: This QI project has been successful in improving the rate of appropriate advice for antipsychotic and lithium monitoring being provided on immediate discharge letters. It is hoped that this will help reduce adverse effects associated with antipsychotics and lithium in older psychiatric patients. …”
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29060por Fisher, Emma“…We first wanted to understand the wellbeing needs of the trainees and what they hoped to get out of an away day. We wanted then to evaluate whether the away day had met these needs. …”
Publicado 2021
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