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29501por Nöhles, Viktor B., Bermpohl, Felix, Falkai, Peter, Reif-Leonhard, Christine, Jessen, Frank, Adli, Mazda, Otte, Christian, Meyer-Lindenberg, Andreas, Bauer, Michael, Rubarth, Kerstin, Anghelescu, Ion-George, Rujescu, Dan, Correll, Christoph U.“…Results of the OASIS-D study are hoped to improve the understanding of the frequency, correlates and 6-month naturalistic treatment and outcome trajectories of different levels of suicidality in hospitalized adults with MDD and suicidality. …”
Publicado 2023
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29502“…Patients believed that N8-GP can offer a long-term impact in areas such as ability to perform day-to-day activities (68%), independence to live like a person without hemophilia (63%), ability to travel (60%) with a feeling of optimism and hopefulness (82%). CONCLUSION: Lower frequency of injections, storage flexibility and improved QoL drove satisfaction and preference for N8-GP over previous treatments among patients with HA.…”
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29503por Handa, Koichi, Thomas, Morgan C., Kageyama, Michiharu, Iijima, Takeshi, Bender, Andreas“…Scientific Contribution This contribution hence illustrates aspects of evaluating the performance of generative models in a real-world setting which have not been extensively described previously and which hopefully contribute to their further future development. …”
Publicado 2023
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29504por Tan, Soo Huei, Normi, Yahaya M, Leow, Adam Thean Chor, Salleh, Abu Bakar, Karjiban, Roghayeh Abedi, Murad, Abdul Munir Abdul, Mahadi, Nor Muhammad, Rahman, Mohd Basyaruddin Abdul“…CONCLUSIONS: We propose that HP Bleg1_2507 is a Sco protein which is able to interact with COXII, its redox partner and therefore, may possess metallochaperone and redox functions similar to other documented bacterial Sco proteins. It is hoped that this scientific effort will help to spur the search for other physiologically relevant proteins among the so-called “orphan” proteins of any given organism.…”
Publicado 2014
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29505por Robinson, Sian, Zincuk, Aleksander, Larsen, Ulla Lei, Ekstrøm, Claus, Toft, Palle“…DISCUSSION: Critically ill unit patients with acute kidney injury present a particular challenge in the provision of thromboprophylaxis. This study hopes to add to the growing evidence that the existing recommendation of 40 mg enoxaparin is inadequate and that 1 mg/kg is both safe and effective for thromboprophylaxis. …”
Publicado 2014
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29506por Recoquillay, Julien, Pitel, Frédérique, Arnould, Cécile, Leroux, Sophie, Dehais, Patrice, Moréno, Carole, Calandreau, Ludovic, Bertin, Aline, Gourichon, David, Bouchez, Olivier, Vignal, Alain, Fariello, Maria Ines, Minvielle, Francis, Beaumont, Catherine, Leterrier, Christine, Le Bihan-Duval, Elisabeth“…Further research will be needed to refine the QTL and confirm or refute the role of candidate genes, which were suggested by bioinformatics analysis. It can be hoped that the identification of genes and polymorphisms related to behavioral traits in the quail will have further applications for other poultry species (especially the chicken) and will contribute to solving animal welfare issues in poultry production. …”
Publicado 2015
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29507por das Nair, Roshan, Lincoln, Nadina B, Ftizsimmons, Deborah, Brain, Nicola, Montgomery, Alan, Bradshaw, Lucy, Drummond, Avril, Sackley, Catherine, Newby, Gavin, Thornton, Jim, Stapleton, Sandip, Pink, Anthony“…DISCUSSION: The study will hopefully provide robust evidence regarding the clinical and cost-effectiveness of a group-based memory rehabilitation intervention for civilians and military personnel following TBI. …”
Publicado 2015
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29508por Xu, Huiwen, Zhang, Weijun, Wang, Xiaohua, Yuan, Jiaqi, Tang, Xinfeng, Yin, Yi, Zhang, Shengfa, Zhou, Huixuan, Qu, Zhiyong, Tian, Donghua“…In addition, several influence factors were significantly different in males and females, such as being currently married (unmarried vs married, AOR = 1.84, p = 0.027, for females; no difference for males), feeling hopeless (hopless vs hopeful, AOR = 1.92, p = 0.06, for females; no difference for males), having other insurances (having other insurances vs having basic employee medical insurance, AOR = 1.92, p = 0.044, for males; no difference for females), having debts (having debts vs no debts, AOR = 2.69, p = 0.001, for males; no difference for females), currently smoking (smoking vs nonsmoking, AOR = 3.01, p = 0.019 for females, no difference for males), and currently drinking (drinking vs nondrinking, AOR = 2.01, p = 0.022, for males; no difference for females). …”
Publicado 2015
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29509por Hochheiser, Harry, Ning, Yifan, Hernandez, Andres, Horn, John R, Jacobson, Rebecca, Boyce, Richard D“…By presenting annotation tasks to both pharmacy experts and relatively naïve participants, we hoped to demonstrate the feasibility of using nonexpert annotators for drug-drug information annotation. …”
Publicado 2016
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29510por Frost, Barry G., Turrell, Megan, Sly, Ketrina A., Lewin, Terry J., Conrad, Agatha M., Johnston, Suzanne, Tirupati, Srinivasan, Petrovic, Kerry, Rajkumar, Sadanand“…CONCLUSIONS: This paper demonstrates that a recovery-oriented model can be successfully implemented at the intermediate level of care. It is hoped that ongoing evaluations support the enthusiasm, commitment and feedback evident from staff, clients and carers. …”
Publicado 2017
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29511por Janahi, Ibrahim A., Khan, Shabina, Chandra, Prem, Al-Marri, Noora, Saadoon, Ammar, Al-Naimi, Lolwa, Al-Thani, Maryam, Greer, William“…Our proposed clinical algorithm and scoring system hopes to empower physicians to accurately predict patients with a high likelihood of FBA.…”
Publicado 2017
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29512por Bull, Eleanor Rose, Mason, Corina, Junior, Fonseca Domingos, Santos, Luana Vendramel, Scott, Abigail, Ademokun, Debo, Simião, Zeferina, Oliver, Wingi Manzungu, Joaquim, Fernando Francisco, Cavanagh, Sarah M.“…Applying behavioural science helped to collect feasible evaluation data and hopefully improved impact and sustainability.…”
Publicado 2017
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29513“…This study protocol gives a detailed description of the usage and dosage of the topical compound TwHF gel and the methodology of this study. In addition, it is hoped that the outcomes of this study will be viewed as supporting the generalizability of CET in the setting of inflammatory rheumatic diseases. …”
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29514por Gomez, Ivan Neil, Lai, Cynthia YY, Yung, Trevor WK, Chan, Chetwyn CH, Tsang, Hector WH“…Furthermore, our findings can lead to the development of innovative evidence-informed evaluation and intervention programs aimed at migrant children's needs. Likewise, it is hoped that this review can be an impetus to inform health and sociopolitical policies responsive of migrant children's current contexts. …”
Publicado 2018
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29515por Stirnadel-Farrant, Heide, Kudari, Mahesh, Garman, Nadia, Imrie, Jessica, Chopra, Bikramjit, Giannelli, Stefania, Gabaldo, Michela, Corti, Ambra, Zancan, Stefano, Aiuti, Alessandro, Cicalese, Maria Pia, Batta, Rohit, Appleby, Jonathan, Davinelli, Mario, Ng, Pauline“…Using practical and cost-efficient approaches, the Strimvelis registry is hoped to encourage further innovation in registry design within orphan drug development.…”
Publicado 2018
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29516por Mitchell, Rebecca, Hopcroft, Lisa E M, Baquero, Pablo, Allan, Elaine K, Hewit, Kay, James, Daniel, Hamilton, Graham, Mukhopadhyay, Arunima, O’Prey, Jim, Hair, Alan, Melo, Junia V, Chan, Edmond, Ryan, Kevin M, Maguer-Satta, Véronique, Druker, Brian J, Clark, Richard E, Mitra, Subir, Herzyk, Pawel, Nicolini, Franck E, Salomoni, Paolo, Shanks, Emma, Calabretta, Bruno, Holyoake, Tessa L, Helgason, G Vignir“…By modeling ponatinib resistance and testing samples from these CML patients, it is hoped that an alternative drug target can be identified and inhibited with a novel compound. …”
Publicado 2017
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29517por Spicer, Neil, Hamza, Yashua Alkali, Berhanu, Della, Gautham, Meenakshi, Schellenberg, Joanna, Tadesse, Feker, Umar, Nasir, Wickremasinghe, Deepthi“…BACKGROUND: Donors often fund projects that develop innovative practices in low and middle-income countries, hoping recipient governments will adopt and scale them within existing systems and programmes. …”
Publicado 2018
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29518por Lisboa, Miguelhete, Fronteira, Inês, Colove, Estefano, Nhamonga, Marques, Martins, Maria do Rosário O.“…BACKGROUND: The GeneXpert MTB/RIF Assay (Xpert®) is known to be a feasible, effective and a hopeful tool for rapid tuberculosis (TB) diagnosis and treatment. …”
Publicado 2019
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29519por Wheeler, Graham M., Mander, Adrian P., Bedding, Alun, Brock, Kristian, Cornelius, Victoria, Grieve, Andrew P., Jaki, Thomas, Love, Sharon B., Odondi, Lang’o, Weir, Christopher J., Yap, Christina, Bond, Simon J.“…Provision of key resources in this contemporary guidance paper will hopefully improve the uptake of the CRM in phase I dose-finding trials. …”
Publicado 2019
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29520por Tapera, O., Kadzatsa, W., Nyakabau, A. M., Mavhu, W., Dreyer, G., Stray-Pedersen, B., SJH, Hendricks“…In the community survey, stratified random sampling was conducted to select 143 healthy women in Glen View, Cranborne, Highlands and Hopely communities of Harare to present high, medium, low density suburbs and rural areas respectively. …”
Publicado 2019
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