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  1. 29641
    “…This understanding will hopefully facilitate the development of novel targeted therapies.…”
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    Infectious Disease Risk in Dialysis Patients: A Transdisciplinary Approach
  2. 29642
    “…A new delivery system for lanreotide depot/autogel was developed in conjunction with patients, caregivers and HCPs. It is hoped that the ergonomic, robust and intuitive delivery system will further improve patient care. …”
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    MON-022 Enhancing Patient Care: Co-Creation and Validation of a New and Improved Delivery System for Lanreotide Depot/Autogel and Its Evaluation by US Healthcare Professionals
  3. 29643
    “…These findings provide an important basis for understanding the molecular and cellular mechanism of EIS and the mouse model offers a potential new way to study rare genetic receptor mutations in humans with hopes of developing a viable therapeutic approach.…”
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    SAT-205 ESR1 Q375H and R394H Mutants Associated with Estrogen Insensitivity Syndrome Mediate Genome-Wide Genetic and Epigenetic Aberrances
  4. 29644
    por Liu, Angela, Johnson, Michelle
    Publicado 2019
    “…The patient was started on propranolol 20 mg PRN and PTU 100 mg PO TID, chosen because she hoped to become pregnant once euthyroid. She was discharged home with outpatient endocrinology follow-up. …”
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    SAT-599 Propylthiouracil-Induced Anaphylaxis with Subsequent Tolerance of Methimazole
  5. 29645
    “…Presentation of this case will hopefully help pediatric specialist to recognize and test for this condition more promptly.…”
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    SUN-594 Skeletal Dysplasia and Growth Failure in Congenital Hypothyroidism Due to a Novel Form of Generalized Thyroid Hormone Resistance
  6. 29646
    “…This study should allow better understanding of prematurity-related defects, leading hopefully to better management of premature infants from birth to adulthood.…”
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    OR07-4 Preterm Birth and Transgenerational Epigenetic Programming of Hypertension in Mice
  7. 29647
    “…The findings of this trial will be useful to healthcare professionals and patients alike to determine whether further study of this agent is warranted. It is hoped that the development of the infrastructure to deliver a multicentre trial involving molecular radiotherapy dosimetry will lead to further trials in this field. …”
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    Investigating the potential clinical benefit of Selumetinib in resensitising advanced iodine refractory differentiated thyroid cancer to radioiodine therapy (SEL-I-METRY): protocol for a multicentre UK single arm phase II trial
  8. 29648
    “…In the re-education workshops, GMRCs showed a preference for and hoped to learn more about both background knowledge and research progress in the ToMMo. …”
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    A training and education program for genome medical research coordinators in the genome cohort study of the Tohoku Medical Megabank Organization
  9. 29649
    por Handschuh, Luiza
    Publicado 2019
    “…The relations between particular RNA puzzles and other components of leukemic cells and their microenvironment, such as exosomes, are now under investigation. Hopefully, the results of this research will shed the light on these aspects of AML pathogenesis which are still not completely understood.…”
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    Not Only Mutations Matter: Molecular Picture of Acute Myeloid Leukemia Emerging from Transcriptome Studies
  10. 29650
    “…The aim of our study was to detect the copy number variation of the SHE gene in four sheep breeds and to conduct a correlation analysis with economic traits, hoping to provide some reference for sheep breeding. …”
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    Copy Number Variation of the SHE Gene in Sheep and Its Association with Economic Traits
  11. 29651
    “…Moreover, we contacted some Polish wholesalers offering tropical invertebrates (Isopoda and Collembola), used as the food source for frogs, hoping to receive information about locations where those invertebrates were delivered, over the period of one year. …”
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    Undesirable immigrants: hobbyist vivaria as a potential source of alien invertebrate species
  12. 29652
    “…Taken together, our data suggest that miR-10b-5p functions to impede breast carcinoma progression via regulation of its key target genes and hopefully serves as a potential diagnostic and prognostic marker for breast cancer.…”
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    Role of miR-10b-5p in the prognosis of breast cancer
  13. 29653
    “…Surveillance of high-risk individuals is hoped to improve survival outcomes by detection of precursor lesions or early-stage malignancy. …”
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    Genetic counselling and personalised risk assessment in the Australian pancreatic cancer screening program
  14. 29654
    por Yusof, Alhady
    Publicado 2019
    “…An appropriate DNAR order will guide the medical team (doctors and nurses) to avoid unnecessary ‘futile care’, and hopefully lead to ‘better’ personalized care for patients and their families(4).…”
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    Do not attempt resuscitation (DNAR) conversation is not only ICU responsibility: experience as an emergency physician in Qatar
  15. 29655
    por Rajwani, Kapil
    Publicado 2019
    “…These failures to debrief can lead to communication breakdowns within the team.(4) The absence of a debriefing can also lead to improper or inadequate documentation, which can result in clinical error and increased litigation.(5) Organizations such as the Agency for Healthcare Research and Quality advocate for clinical event debriefing; this attention and effort on research and training can hopefully increase the frequency of and comfort with clinical event debriefing.…”
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    Debriefing in critical care
  16. 29656
    “…The aim of the present study was to further evaluate the recombinant Tsol-p27 protein as a target molecule in immunoassays for the serodiagnosis of porcine cysticercosis. From these data, we hoped to develop recommendations regarding its use in the serodiagnosis of porcine cysticercosis. …”
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    Further evaluation of recombinant Tsol-p27 by enzyme-linked immunoelectrotransfer blot for the serodiagnosis of cysticercosis in pigs from Mozambique
  17. 29657
    “…Study duration for each patient will be 60 ± 14 days. DISCUSSION: It is hoped that performing hemiarch surgery using mild hypothermia (32 °C) and selective ACP will result in a 15% absolute risk reduction in the composite outcomes. …”
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    COMMENCE trial (Comparing hypOtherMic teMperaturEs duriNg hemiarCh surgEry): a randomized controlled trial of mild vs moderate hypothermia on patient outcomes in aortic hemiarch surgery with anterograde cerebral perfusion
  18. 29658
    “…Participants’ experiences of eczema over time also had implications for adaptation and finding a balance between accepting eczema as long term and hoping it would go away. This linked to a gradual shift in treatment expectations from ‘cure’ to ‘control’ of eczema. …”
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    ‘It's like the bad guy in a movie who just doesn't die’: a qualitative exploration of young people's adaptation to eczema and implications for self‐care
  19. 29659
    “…Tracking adverse and high-risk profiles of adolescents is hoped to curb CVD progression later in life. The study aims to investigate the clustering of biological CVD risk factor among adolescents in Malaysia and the transitions between clusters over time. …”
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    Clustering and Tracking the Stability of Biological CVD Risk Factors in Adolescents: The Malaysian Health and Adolescents Longitudinal Research Team Study (MyHeARTs)
  20. 29660
    “…Conclusions: Our data for the first time suggest that the natural product β-elemene is a new ferroptosis inducer and combinative treatment of β-elemene and cetuximab is sensitive to KRAS mutant CRC cells by inducing ferroptosis and inhibiting EMT, which will hopefully provide a prospective strategy for CRC patients with RAS mutations.…”
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    Combinative treatment of β-elemene and cetuximab is sensitive to KRAS mutant colorectal cancer cells by inducing ferroptosis and inhibiting epithelial-mesenchymal transformation
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