The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology

por Martinez Hernandez, Ana, Urbanke, Hendrik, Gillman, Alan L, Lee, Joon, Ryazanov, Sergey, Agbemenyah, Hope Y, Benito, Eva, Jain, Gaurav, Kaurani, Lalit, Grigorian, Gayane, Leonov, Andrei, Rezaei‐Ghaleh, Nasrollah, Wilken, Petra, Arce, Fernando Teran, Wagner, Jens, Fuhrman, Martin, Caruana, Mario, Camilleri, Angelique, Vassallo, Neville, Zweckstetter, Markus, Benz, Roland, Giese, Armin, Schneider, Anja, Korte, Martin, Lal, Ratnesh, Griesinger, Christian, Eichele, Gregor, Fischer, Andre
Publicado 2017

De novo ATP1A3 and compound heterozygous NLRP3 mutations in a child with autism spectrum disorder, episodic fatigue and somnolence, and muckle-wells syndrome

por Torres, Alcy, Brownstein, Catherine A., Tembulkar, Sahil K., Graber, Kelsey, Genetti, Casie, Kleiman, Robin J., Sweadner, Kathleen J., Mavros, Chrystal, Liu, Kevin X., Smedemark-Margulies, Niklas, Maski, Kiran, Yang, Edward, Agrawal, Pankaj B., Shi, Jiahai, Beggs, Alan H., D'Angelo, Eugene, Lincoln, Sarah Hope, Carroll, Devon, Dedeoglu, Fatma, Gahl, William A., Biggs, Catherine M., Swoboda, Kathryn J., Berry, Gerard T., Gonzalez-Heydrich, Joseph
Publicado 2018

A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer

por Bangi, Erdem, Ang, Celina, Smibert, Peter, Uzilov, Andrew V., Teague, Alexander G., Antipin, Yevgeniy, Chen, Rong, Hecht, Chana, Gruszczynski, Nelson, Yon, Wesley J., Malyshev, Denis, Laspina, Denise, Selkridge, Isaiah, Rainey, Hope, Moe, Aye S., Lau, Chun Yee, Taik, Patricia, Wilck, Eric, Bhardwaj, Aarti, Sung, Max, Kim, Sara, Yum, Kendra, Sebra, Robert, Donovan, Michael, Misiukiewicz, Krzysztof, Schadt, Eric E., Posner, Marshall R., Cagan, Ross L.
Publicado 2019

Prospective, multicenter study of P4HB (Phasix™) mesh for hernia repair in cohort at risk for complications: 3-Year follow-up

por Roth, John Scott, Anthone, Gary J., Selzer, Don J., Poulose, Benjamin K., Pierce, Richard A., Bittner, James G., Hope, William W., Dunn, Raymond M., Martindale, Robert G., Goldblatt, Matthew I., Earle, David B., Romanelli, John R., Mancini, Gregory J., Greenberg, Jacob A., Linn, John G., Parra-Davila, Eduardo, Sandler, Bryan J., Deeken, Corey R., Verbarg, Jasenka, Salluzzo, Jennifer L., Voeller, Guy R.
Publicado 2020

Adverse outcomes in COVID-19 and diabetes: a retrospective cohort study from three London teaching hospitals

por Izzi-Engbeaya, Chioma, Distaso, Walter, Amin, Anjali, Yang, Wei, Idowu, Oluwagbemiga, Kenkre, Julia S, Shah, Ronak J, Woin, Evelina, Shi, Christine, Alavi, Nael, Bedri, Hala, Brady, Niamh, Blackburn, Sophie, Leczycka, Martina, Patel, Sanya, Sokol, Elizaveta, Toke-Bjolgerud, Edward, Qayum, Ambreen, Abdel-Malek, Mariana, Hope, David C D, Oliver, Nick S, Bravis, Vasiliki, Misra, Shivani, Tan, Tricia M, Hill, Neil E, Salem, Victoria
Publicado 2021

A skin-conformable wireless sensor to objectively quantify symptoms of pruritus

por Chun, Keum San, Kang, Youn J., Lee, Jong Yoon, Nguyen, Morgan, Lee, Brad, Lee, Rachel, Jo, Han Heul, Allen, Emily, Chen, Hope, Kim, Jungwoo, Yu, Lian, Ni, Xiaoyue, Lee, KunHyuck, Jeong, Hyoyoung, Lee, JooHee, Park, Yoonseok, Chung, Ha Uk, Li, Alvin W., Lio, Peter A., Yang, Albert F., Fishbein, Anna B., Paller, Amy S., Rogers, John A., Xu, Shuai
Publicado 2021

Functional Homology for Antibody-Dependent Phagocytosis Across Humans and Rhesus Macaques

por Pollara, Justin, Tay, Matthew Zirui, Edwards, R. Whitney, Goodman, Derrick, Crowley, Andrew R., Edwards, Robert J., Easterhoff, David, Conley, Haleigh E., Hoxie, Taylor, Gurley, Thaddeus, Jones, Caroline, Machiele, Emily, Tuyishime, Marina, Donahue, Elizabeth, Jha, Shalini, Spreng, Rachel L., Hope, Thomas J., Wiehe, Kevin, He, Max M., Moody, M. Anthony, Saunders, Kevin O., Ackerman, Margaret E., Ferrari, Guido, Tomaras, Georgia D.
Publicado 2021

Final overall survival analysis of the phase 3 HERITAGE study demonstrates equivalence of trastuzumab-dkst to trastuzumab in HER2-positive metastatic breast cancer

por Rugo, Hope S., Pennella, Eduardo J., Gopalakrishnan, Unmesh, Hernandez-Bronchud, Miguel, Herson, Jay, Koch, Hans Friedrich, Loganathan, Subramanian, Deodhar, Sarika, Marwah, Ashwani, Manikhas, Alexey, Bondarenko, Igor, Mukhametshina, Guzel, Nemsadze, Gia, Parra, Joseph D., Abesamis-Tiambeng, Maria Luisa T., Baramidze, Kakhaber, Akewanlop, Charuwan, Vynnychenko, Ihor, Sriuranpong, Virote, Mamillapalli, Gopichand, Roy, Sirshendu, Yanez Ruiz, Eduardo Patricio, Barve, Abhijit, Fuentes-Alburo, Adolfo, Waller, Cornelius F.
Publicado 2021

COVID-19-Related Mental Health Burdens: Impact of Educational Level and Relationship Status Among Low-Income Earners of Western Uganda

por Lemuel, Ann Monima, Usman, Ibe Michael, Kasozi, Keneth Iceland, Alghamdi, Saad, Aigbogun, Eric Osamudiamwen, Archibong, Victor, Ssebuufu, Robinson, Kabanyoro, Annet, Ifie, Josiah Eseoghene, Swase, Dominic Terkimbi, Ssempijja, Fred, Ayuba, John Tabakwot, Matama, Kevin, Onohuean, Hope, Kembabazi, Stellamaris, Henry, Rachael, Odoma, Said, Yusuf, Helen, Afodun, Adam Moyosore, Assaggaf, Hamza M., Kairania, Emmanuel, Aslam, Akhmed, Okon, Owoisinke, El-Saber Batiha, Gaber, Welburn, Susan Christina
Publicado 2021

Reduced Magnitude and Durability of Humoral Immune Responses to COVID-19 mRNA Vaccines Among Older Adults

por Brockman, Mark A, Mwimanzi, Francis, Lapointe, Hope R, Sang, Yurou, Agafitei, Olga, Cheung, Peter K, Ennis, Siobhan, Ng, Kurtis, Basra, Simran, Lim, Li Yi, Yaseen, Fatima, Young, Landon, Umviligihozo, Gisele, Omondi, F Harrison, Kalikawe, Rebecca, Burns, Laura, Brumme, Chanson J, Leung, Victor, Montaner, Julio S G, Holmes, Daniel, DeMarco, Mari L, Simons, Janet, Pantophlet, Ralph, Niikura, Masahiro, Romney, Marc G, Brumme, Zabrina L
Publicado 2021

PPARα and PPARγ activation is associated with pleural mesothelioma invasion but therapeutic inhibition is ineffective

por Orozco Morales, M. Lizeth, Rinaldi, Catherine A., de Jong, Emma, Lansley, Sally M., Gummer, Joel P.A., Olasz, Bence, Nambiar, Shabarinath, Hope, Danika E., Casey, Thomas H., Lee, Y. C. Gary, Leslie, Connull, Nealon, Gareth, Shackleford, David M., Powell, Andrew K., Grimaldi, Marina, Balaguer, Patrick, Zemek, Rachael M., Bosco, Anthony, Piggott, Matthew J., Vrielink, Alice, Lake, Richard A., Lesterhuis, W. Joost
Publicado 2021

Development of an In Vivo Probe to Track SARS-CoV-2 Infection in Rhesus Macaques

por Madden, Patrick J., Arif, Muhammad S., Becker, Mark E., McRaven, Michael D., Carias, Ann M., Lorenzo-Redondo, Ramon, Xiao, Sixia, Midkiff, Cecily C., Blair, Robert V., Potter, Elizabeth Lake, Martin-Sancho, Laura, Dodson, Alan, Martinelli, Elena, Todd, John-Paul M., Villinger, Francois J., Chanda, Sumit K., Aye, Pyone Pyone, Roy, Chad J., Roederer, Mario, Lewis, Mark G., Veazey, Ronald S., Hope, Thomas J.
Publicado 2021

Comparative analysis of the risks of hospitalisation and death associated with SARS-CoV-2 omicron (B.1.1.529) and delta (B.1.617.2) variants in England: a cohort study

por Nyberg, Tommy, Ferguson, Neil M, Nash, Sophie G, Webster, Harriet H, Flaxman, Seth, Andrews, Nick, Hinsley, Wes, Bernal, Jamie Lopez, Kall, Meaghan, Bhatt, Samir, Blomquist, Paula, Zaidi, Asad, Volz, Erik, Aziz, Nurin Abdul, Harman, Katie, Funk, Sebastian, Abbott, Sam, Hope, Russell, Charlett, Andre, Chand, Meera, Ghani, Azra C, Seaman, Shaun R, Dabrera, Gavin, De Angelis, Daniela, Presanis, Anne M, Thelwall, Simon
Publicado 2022

Therapeutic efficacy of an Ad26/MVA vaccine with SIV gp140 protein and vesatolimod in ART-suppressed rhesus macaques

por Ventura, John D., Nkolola, Joseph P., Chandrashekar, Abishek, Borducchi, Erica N., Liu, Jinyan, Mercado, Noe B., Hope, David L., Giffin, Victoria M., McMahan, Katherine, Geleziunas, Romas, Murry, Jeffrey P., Yang, Yunling, Lewis, Mark G., Pau, Maria G., Wegmann, Frank, Schuitemaker, Hanneke, Fray, Emily J., Kumar, Mithra R., Siliciano, Janet D., Siliciano, Robert F., Robb, Merlin L., Michael, Nelson L., Barouch, Dan H.
Publicado 2022

Evolution of zygomycete secretomes and the origins of terrestrial fungal ecologies

por Chang, Ying, Wang, Yan, Mondo, Stephen, Ahrendt, Steven, Andreopoulos, William, Barry, Kerrie, Beard, Jeff, Benny, Gerald L., Blankenship, Sabrina, Bonito, Gregory, Cuomo, Christina, Desiro, Alessandro, Gervers, Kyle A., Hundley, Hope, Kuo, Alan, LaButti, Kurt, Lang, B. Franz, Lipzen, Anna, O’Donnell, Kerry, Pangilinan, Jasmyn, Reynolds, Nicole, Sandor, Laura, Smith, Matthew E., Tsang, Adrian, Grigoriev, Igor V., Stajich, Jason E., Spatafora, Joseph W.
Publicado 2022

Long-Term, Prospective, Multicenter Study of Poly-4-Hydroxybutyrate Mesh (Phasix Mesh) for Hernia Repair in Cohort at Risk for Complication: 60-Month Follow-Up

por Roth, John Scott, Anthone, Gary J, Selzer, Don J, Poulose, Benjamin K, Pierce, Richard A, Bittner, James G, Hope, William W, Dunn, Raymond M, Martindale, Robert G, Goldblatt, Matthew I, Earle, David B, Romanelli, John R, Mancini, Gregory J, Greenberg, Jacob A, Linn, John G, Parra-Davila, Eduardo, Sandler, Bryan J, Deeken, Corey R, Badhwar, Amit, Salluzzo, Jennifer L, Voeller, Guy R
Publicado 2022

Blockade of TGF-β signaling reactivates HIV-1/SIV reservoirs and immune responses in vivo

por Samer, Sadia, Thomas, Yanique, Araínga, Mariluz, Carter, Crystal, Shirreff, Lisa M., Arif, Muhammad S., Avita, Juan M., Frank, Ines, McRaven, Michael D., Thuruthiyil, Christopher T., Heybeli, Veli B., Anderson, Meegan R., Owen, Benjamin, Gaisin, Arsen, Bose, Deepanwita, Simons, Lacy M., Hultquist, Judd F., Arthos, James, Cicala, Claudia, Sereti, Irini, Santangelo, Philip J., Lorenzo-Redondo, Ramon, Hope, Thomas J., Villinger, Francois J., Martinelli, Elena
Publicado 2022

Evaluating the effectiveness and implementation of evidence-based early-life nutrition interventions in a community setting a hybrid type 1 non-randomized trial – the Nutrition Now...

por Øverby, Nina Cecilie, Hillesund, Elisabet Rudjord, Helland, Sissel Heidi, Helle, Christine, Wills, Andrew Keith, Lamu, Admassu Nadew, Osorio, Natalie Garzon, Lian, Henrik, Ersfjord, Torunn Iveland, Van Daele, Wim, Bjørkkjær, Tormod, Valen, Erlend Nuland, Gebremariam, Mekdes Kebede, Grasaas, Erik, Kiland, Charlotte, Schwarz, Ulrica von Thiele, Abel, Marianne Hope, Love, Penny, Campbell, Karen, Rutter, Harry, Barker, Mary Elizabeth, Vik, Frøydis Nordgård, Medin, Anine Christine
Publicado 2023

Feasibility of a virtual reality intervention targeting distress and anxiety symptoms in patients with primary brain tumors: Interim analysis of a phase 2 clinical trial

por King, Amanda L., Roche, Kayla N., Leeper, Heather E., Vera, Elizabeth, Mendoza, Tito, Mentges, Kelly, Acquaye, Alvina A., Adegbesan, Kendra, Boris, Lisa, Burton, Eric, Choi, Anna, Grajkowska, Ewa, Kunst, Tricia, Levine, Jason, Lollo, Nicole, Miller, Hope, Panzer, Marissa, Penas-Prado, Marta, Pillai, Valentina, Polskin, Lily, Reyes, Jennifer, Sahebjam, Solmaz, Stockdill, Macy, Theeler, Brett J., Wu, Jing, Gilbert, Mark R., Armstrong, Terri S.
Publicado 2023

PSMA PET/CT: joint EANM procedure guideline/SNMMI procedure standard for prostate cancer imaging 2.0

por Fendler, Wolfgang P., Eiber, Matthias, Beheshti, Mohsen, Bomanji, Jamshed, Calais, Jeremie, Ceci, Francesco, Cho, Steve Y., Fanti, Stefano, Giesel, Frederik L., Goffin, Karolien, Haberkorn, Uwe, Jacene, Heather, Koo, Phillip J., Kopka, Klaus, Krause, Bernd J., Lindenberg, Liza, Marcus, Charles, Mottaghy, Felix M., Oprea-Lager, Daniela E., Osborne, Joseph R., Piert, Morand, Rowe, Steven P., Schöder, Heiko, Wan, Simon, Wester, Hans-Jürgen, Hope, Thomas A., Herrmann, Ken
Publicado 2023