“…One of the greatest challenges facing the computational engineering community is to extend the success of computational mechanics to fields outside traditional engineering, in particular to biology, the biomedical sciences, and medicine. We hope the research presented within this book series will contribute to overcoming this grand challenge.…”
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“…All chapters in the book discuss theoretical and practical issues connected with computational methods and optimization methods for knowledge engineering. The editors hope that this volume can be useful for graduate and Ph.D. students and researchers in Applied Sciences, Computer Science and Applied Mathematics. .…”
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“…One of the greatest challenges facing the computational engineering community is to extend the success of computational mechanics to fields outside traditional engineering, in particular to biology, the biomedical sciences, and medicine. We hope the research presented within this book series will contribute to overcoming this grand challenge.…”
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“…Research activities in the natural sciences, and especially those in the field of pure research work as opposed to applied research, are being financially supported for various reasons, probably the least of which is the hope for a quick economic return. It has, nevertheless, been realised for a number of years that benefits of one sort or another may appear in various and sometimes unexpected ways, where these be— nefits are not the direct consequence of the applica— tion of a research result. …”
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“…Though the authors have no definitive solution to the problem, they offer this contribution in an attempt to define the problem as they see it, and to sketch out several obvious attempts that have been suggested to solve the problem and which seem to have failed. They hope that by being available to the general mathematical community, they will inspire others to consider–and hopefully solve–the problem. …”
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“…The reported simulations carried out with the CLIC main beam parameters of the LC97 workshop corroborate this hope. They show that the vertical emittance growth of a 60-bunch train accelerated to 1 TeV is only a fraction larger than the single-bunch emittance growth, in the same conditions.…”
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“…A possible relation between the string theory and the toy model is studied in the case of a massive particle propagating in AdS/sub 5/ space: a generalized twistor construction is shown to lead to a quadratic action and simple BRST quantization. We hope that these results will help to also eventually quantize the string on ad S/sub 5/*S/sup 5/. (10 refs).…”
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“…They do not know anything about the family, but hope that they are also safe in England. Pauli himself feels very well in Princeton and belongs to the few people in the world who can continue their scientific work during the war. …”
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“…These reactions proceed via initial reversible addition, followed by a variety of transformations that are common for the adducts of both aliphatic and aromatic electrophiles. We hope that understanding of this analogy should help to expand the scope of the known reactions and inspire the search for new reactions that were overlooked.…”
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“…New technology, however, offers the hope of making chemical data (compounds and properties) free during the authoring process. …”
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“…This article makes the case for teaching life-supporting first aid to the public in the hope that one day, should another such incident occur, they would be able to preserve injured victims until formal rescue occurs.…”
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“…In this review we discuss the development of this complication during mechanical ventilation, techniques to measure it and strategies to limit its severity. We hope that by understanding such concepts clinicians will be able to reduce further the poor outcomes occasionally related to severe asthma.…”
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“…Two techniques under development identify aflatoxin-tainted corn by using infrared light to elicit telltale sounds and light from contaminated kernels. Other scientists hope to protect corn from A. flavus in the first place by designing genetically engineered aflatoxin-resistant grain species and by working with drugs such as oltipraz that reportedly detoxify aflatoxin already in the body.…”
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“…Additionally, attention is drawn to the need for increased research to fill the gaps in our knowledge in these vital areas, all in the hope of permitting a more facile identification and quantification of the potential hazard to exposure to these agents.…”
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“…We also discuss novel therapies that may improve the efficacy of trastuzumab, and that offer hope that the survival of breast cancer patients with HER2-overexpressing tumors can be vastly improved.…”
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“…This article reviews the various strategies adopted by clinicians in the hope of increasing the response rate of current antidepressants to obtain full remission and/or to overcome treatment-resistant depression.…”
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“…The Ministry of Health and cancer research organisations struggled to find a fair and honest way to inform the public and affected families about childhood leukaemia without raising or crushing hope.…”
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“…The Grid is touted as a next generation Internet/Web, designed primarily to support e-Science. I hope to shed some light on what the Grid is, its purpose, and its potential impact on scientific practice in biology. …”
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“…Three general areas are discussed: (1) amplification of target sequences using the polymerase chain reaction or the transcript amplification system, (2) amplification of the probe sequences using Q beta replicase, and (3) amplification of probe-generated signals with compound or "Christmas tree" probes. The hope of these new technologies is to simplify yet improve on the sensitivity of nucleic acid-based tests to enable them to attain a more prominent place in the diagnostic repertoire of the clinical laboratory.…”
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“…We now seek to draw these various observations together into a conclusion, with the hope that this will inform further work in this area and result in the identification of new therapeutic targets that will have a disease modifying effect.…”
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