“…We present a short case series of elderly patients with NK-AML and isolated NPM1 mutation who were treated with intensive chemotherapy, achieving significant CRs multiple times on reinduction, even with a single course.We hope to highlight the NPM1 as a molecular marker in elderly for consideration of aggressive treatment, even if abridged, as this subset may achieve a durable, good quality responses at diagnosis or subsequent relapses.…”
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“…We present two cases of cerebral shunts - a ventriculopleural shunt and a ventriculoperitoneal shunt, with their associated complications. We also hope to provide a comprehensive literature review on various imaging modalities, including nuclear medicine studies in evaluating cerebral shunt complications.…”
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“…Recent exciting results from clinical studies of small numbers of patients treated with human embryonic stem cell-derived retinal pigment epithelial cells may provide hope for affected individuals.…”
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“…In all, it was a thoroughly worthwhile adventure and one that we hope to replicate every two years.…”
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“…With this new technology, researchers hope to find clinically appropriate biomarkers for a myriad of illnesses by screening human body fluids. …”
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“…We aim to provide a comprehensive summary of the current state of affairs with the contract negotiations and hope to inform those who may not be familiar with the situation affecting junior doctors in the NHS.…”
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“…We report a case of BCC on the sole of the foot and its treatment in the hope to facilitate its detection.…”
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“…Indeed, we propose that schistosomiasis is fundamentally as disease of stem cells. We hope this review will attract new interest in the basic developmental biology of these important organisms.…”
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“…Although we still wait for important breakthroughs, there is grounds for hope that better therapeutic options will be available in the near future.…”
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“…This supplement to the guide issued by the College, based on our own experience, describes in more detail the preparation and management of the examination in the hope that it will ease our colleagues' tasks.…”
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“…Increasing knowledge concerning the pathophysiology of cerebellar disease in MS from human postmortem studies, experimental models, and clinical trials has raised the hope that cerebellar symptoms will be better treated in the future.…”
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“…This article wishes to point out some of the main characteristics of this disease and the involved proteins by referring to the history, the pathogenesis, the histology, the diagnosis and a few aspects of the prognosis of this disease in the hope that future research will bring to light the answers for the mystery of amyloidosis along with more efficient therapies.…”
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“…The mainstay of treatment of such lesions remains radiotherapy in various forms, however, photodynamic therapy does have a useful role to play in the management of such patients. In this article, I hope to review the current indications, treatment regimes, and the risks and benefits of photodynamic therapy (PDT) as a treatment for eye cancer.…”
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“…In metastatic disease, they provide hope of durable response where “best-case” scenario has long been inadequate. …”
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“…While the treatment of adult insomnia has been standardized, the treatment of pediatric insomnia is very practitioner-dependent and few large-scale studies are available to determine a standard recommended practice. There is great hope that as the adolescent medicine and sleep medicine fields flourish, larger cohort analyses will be performed to determine the prevalence and precipitating factors of adolescent insomnia, allowing for standardized treatment recommendations and systematic efforts to make these recommendations available to all adolescents.…”
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“…Overall prognosis is poor, but novel therapies that have emerged in recent years offer hope that outcomes can improve. In this comprehensive presentation, speakers covered a broad array of topics, including diagnostic workup, risk stratification, and novel therapeutic agents, and walked listeners through three illustrative case presentations.…”
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“…This was thought to be related to severely depressed ejection fraction from non-ischemic etiology, presumably chronic alcohol ingestion. We hope that awareness of SPG and association with a low output state will aid in early detection and prevention.…”
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“…It refers to the possibility that even in the presence of a chronic psychiatric disorder there is hope for a life that has value. The affected individual can still make a contribution to society; he or she can expect to live independently and with dignity. …”
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“…Developing a better understanding of how the disease originates and progresses will, we hope, lead to new therapies. The ASAP initiative will incentivize collaboration between the existing PD research community and other researchers and will be committed to open-science practices.…”
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“…This review article represents the first one on this argument and is thought to give a first overview on these compounds with the hope that their study may continue and increase, after this.…”
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