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6301“…The importance of different root traits and genes for breeding P-efficient roots in rice varieties for Pi-deficient soils are also discussed, which we hope will benefit the genetic improvement of Pi uptake, Pi-use efficiency, and crop yields.…”
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6302por Kuźmiński, Andrzej, Rosada, Tomasz, Przybyszewska, Justyna, Ukleja-Sokołowska, Natalia, Bartuzi, Zbigniew“…Glucocorticosteroids and other immunomodulatory drugs are the mainstay of treatment, but currently the greatest hope lies in biological drugs, which are undergoing intensive research. …”
Publicado 2022
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6303“…In addition, our syntheses also highlight gaps in our current understanding of M. oryzae development and virulence. We hope this review will serve to improve a comprehensive understanding of M. oryzae and assist disease control strategy designs in the future.…”
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6304“…Within this review, we hope to illustrate the role that macrophages and microglia play as initiators of adaptive immune response in various CNS diseases by offering evidence of: (1) the types of immune responses and the processes of antigen presentation in each disease, (2) receptors involved in macrophage/microglial phagocytosis of disease-related cell debris or molecules, and, finally, (3) the implications of macrophages/microglia on the pathogenesis of the diseases.…”
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6305“…Here, we report a case of atypical symptoms of cardiac infarction caused by a PD-1 inhibitor used in the treatment of ureteral SCNEC and hope to address concerns regarding the possible cardiac toxicity caused by PD-1/PD-L1 inhibitors in ureteral SCNEC patients.…”
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6306por Lin, Liyang, Guo, Wei, Li, Mengjun, Qing, Juan, Cai, Chuang, Yi, Ping, Deng, Qibo, Chen, Wei“…At the end of this review, some drawbacks of glass-ceramic SSEs are summarized, and future development directions are prospected. We hope that this review paper can help the development of glass-ceramic solid-state electrolytes.…”
Publicado 2023
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6307“…Despite this, there seems to be hope for treatment plans that focus on addressing possible etiologies and creating a path to improving quality of life and a paced return to activity.…”
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6308por Jensen, Nele“…But it also expresses a hope that lessons from the pandemic will eventually serve to challenge prevailing (economic) policy orthodoxy and feed a collective demand for more progressive social, economic and environmental justice-oriented politics.…”
Publicado 2023
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6309por Balsano, Rita, Zanuso, Valentina, Pirozzi, Angelo, Rimassa, Lorenza, Bozzarelli, Silvia“…This failure mirrors the lack of knowledge about the real key players of immune system senescence and the complexity of the tumor microenvironment in PDAC. However, some hope can be derived from PARP-inhibitor combinations, vaccines, and CAR-T-cells therapy. …”
Publicado 2023
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6310por Tang, Hiu, Kulkarni, Sanat, Peters, Christina, Eddison, Jasper, Al-Ani, Maryam, Madhusudan, Srinivasan“…Recently, the DNA-repair-directed precision oncology strategy has generated hope for patients. The clinical use of poly(ADP-ribose) polymerase (PARP) inhibitors in BRCA germ-line-deficient and/or platinum-sensitive epithelial ovarian cancers has improved survival. …”
Publicado 2023
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6311“…We also discuss the challenges associated with the development of AI models for drug metabolism and excretion prediction and explore future perspectives in the field. We hope this will be a helpful resource for anyone who is researching in silico drug metabolism, excretion, and pharmacokinetic properties.…”
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6312“…Prior to presenting at our center, she was given no hope or much in terms of treatment options. She was found to have a substantial mass over the body and tail of pancreas with characteristic and typical gross as well as histological features. …”
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6313“…Overall, this review provided novel insights for clinical treatment of silicosis with the hope of bridging the gap between research and practice in silicosis.…”
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6314por Galinier, Anne, Delan-Forino, Clémentine, Foulquier, Elodie, Lakhal, Hakima, Pompeo, Frédérique“…By summarizing the latest findings in this field, we hope to provide a comprehensive overview of peptidoglycan biology, which is critical for our understanding of bacterial adaptation and antibiotic resistance.…”
Publicado 2023
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6315“…Recent clinical trials have demonstrated the efficacy of these novel treatments, including Food and Drugs Association (FDA) drug approvals, offering hope for improved patient outcomes. Overall, this review emphasizes the importance of understanding the interplay between MMR and DSB defects in prostate cancer to develop innovative and effective therapeutic strategies for patients.…”
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6316“…By assessing the strengths and weaknesses of particular antigens, as well as methods for delivering these antigens to mucosal sites, we hope to guide future research toward an effective mucosal vaccine against CDI.…”
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6317por Raimondi, Raffaele, D’Esposito, Fabiana, Sorrentino, Tania, Tsoutsanis, Panos, De Rosa, Francesco Paolo, Stradiotto, Elisa, Barone, Gianmaria, Rizzato, Angelica, Allegrini, Davide, Costagliola, Ciro, Romano, Mario R.“…Through this review, we hope to contribute to the establishment of state-of-the-art genetic counselling services for inherited macular dystrophies.…”
Publicado 2023
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6318“…In this review, results from recent studies on this topic are discussed in order to build the argument for blueberries to possibly be an effective agent for skin health. In addition, we hope to highlight the need for further research to elucidate the mechanisms behind the use of both topical application and dietary supplementation with blueberries to bolster cutaneous systems and defensive mechanisms.…”
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6319“…The possibility of HSP-targeted novel molecular therapeutics has generated much interest and hope in recent years. In this review, we discuss the role of Extracellular Heat Shock Proteins (Ec-HSPs) in various disease states, with a particular focus on cardiovascular diseases.…”
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6320por Białek, Michał“…I conclude by urging scientists to research this effect with the hope of having a lasting positive impact on society.…”
Publicado 2023
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