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  1. 6581
    por Martikainen, Miika, Essand, Magnus
    Publicado 2019
    “…Although clinical testing of oncolytic viruses against GBM is at an early stage, the promising results from these trials give hope for the effective treatment of GBM in the near future.…”
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  2. 6582
    “…Although the main focus is on classical molecular dynamics simulations, we also provide the reader with some insights into other computational techniques, such as the COSMO-method, and also discuss Flory-Huggins theory and solubility parameters. We hope that this review will serve as a valuable starting point for any pharmaceutical researcher, who has not yet fully explored the possibilities offered by computational approaches to solubility calculations.…”
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  3. 6583
    por de Jonge, Jan, Peeters, Maria C.W.
    Publicado 2019
    “…With this Special Issue, we hope to provide readers with solid new findings extending the current state of knowledge about employee vitality and sustainable work performance.…”
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  4. 6584
    “…In addition, we highlight the open questions surrounding the viral restriction protein IFITM3 with the hope that by answering some of these questions we can elucidate the mechanism of IFITM3 viral restriction and therefore how this restriction is altered due to the rs12252 polymorphism.…”
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  5. 6585
    “…By emphasizing these unique activities of satellite DNAs and transposable elements, we hope to disparage the conventional exemplification of repetitive DNA in the historically-associated context of ‘junk’.…”
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  6. 6586
    “…This review focuses on the progress in our understanding of the biological activities of fucoidan, highlighting its benefits for the treatment of human disease. We hope that this review can provide some theoretical basis and inspiration for the product development of fucoidan.…”
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  7. 6587
    “…The emergence of wireless body area network (WBAN) technology has brought hope and dawn to solve the problems of population aging, various chronic diseases, and medical facility shortage. …”
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  8. 6588
    por Puglisi, Rita, Pastore, Annalisa
    Publicado 2018
    “…We critically evaluated the literature and highlighted the weak aspects which will require more attention in the future. We sincerely hope that this study will inspire new interest on this important and interesting system.…”
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  9. 6589
    “…The advantages and disadvantages of each method were also discussed with the hope that this review can serve as a resource for selection of surface modification of aliphatic products.…”
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  10. 6590
    por Yue, Xihua, Qian, Yi, Gim, Bopil, Lee, Intaek
    Publicado 2019
    “…In this review, we aim to give a timely overview of recent findings on this protein, including its emerging role in membrane domain organization at the Golgi and the mitochondria. We hope that this review provides readers with useful insights on how ACBD3 may contribute to membrane domain organization along the secretory pathway and on the cytoplasmic surface of intracellular organelles, which influence many important physiological and pathophysiological processes in mammalian cells.…”
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  11. 6591
    por Jin, Kunlin
    Publicado 2019
    “…In gaining a better understanding of the inevitable aging process, the hope is to preserve, promote, or delay healthy aging through the treatment of common age-associated diseases. …”
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  12. 6592
    por Sousa, Rui, Lafer, Eileen M.
    Publicado 2019
    “…In this review we address persistent misconceptions regarding the dynamics of proteins in solution that contribute to this lack of understanding, and we clarify the basic physics of entropic pulling with some simple analogies. We hope that increased understanding of the entropic pulling mechanism will inform future efforts to characterize how Hsp70s function as motors, and how they coordinate with their regulatory cochaperones in mechanochemical cycles that transduce the energy of ATP hydrolysis into physical changes in their protein substrates.…”
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  13. 6593
    “…The social, medical conditions, and the resourses of Turkey have also been taken into consideration in its preparation. We hope it will be useful for all pediatricians and neonatologists for use as a essential guideline in delivery room care.…”
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  14. 6594
    “…The steps taken to monitor and solve the problems of all high-risk infants may vary. We hope the use of such a standard approach in evaluating each infant in daily routine will improve the life quality of these high-risk infants.…”
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  15. 6595
    por Surana, Neeraj K.
    Publicado 2019
    “…The recognition over the past decade that nearly all diseases are associated with changes in the microbiome has raised hope that microbiome-based therapeutics may cure many human ailments. …”
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  16. 6596
    “…By highlighting these differences, we hope to provide a clear, defined approach to acetabular placement and sizing for direct anterior-approach total hip arthroplasty.…”
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  17. 6597
    “…In this review, we summarize current knowledge about the bioactive compounds and bioactivities of ginger, and the mechanisms of action are also discussed. We hope that this updated review paper will attract more attention to ginger and its further applications, including its potential to be developed into functional foods or nutraceuticals for the prevention and management of chronic diseases.…”
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  18. 6598
    “…The purpose of this review is to provide a new point of view and current status in droplet-based microfluidics to biochemists and molecular biologists. We hope that this review will accelerate communications between researchers who are working in droplet-based microfluidics, biochemistry and molecular biology.…”
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  19. 6599
    “…In describing this case, we hope to educate and inform other gynaecological oncologists facing a similar surgical challenge. …”
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  20. 6600
    por Su, Tsung-Ping
    Publicado 2019
    “…This perspective diverts attention to those underrecognized targets, in the hope of promoting a more complete understanding of the action of drugs of abuse.…”
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