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  1. 6741
    “…In this review, we address the 4 major classes of demyelinating disease: multiple sclerosis (MS), neuromyelitis optica (NMO), anti-MOG-associated encephalomyelitis (MOG-EM), and acute disseminated encephalomyelitis (ADEM), and discuss their prevalence, demographics, clinical diagnosis workup, and imaging features in the Indonesian population, as well as the challenges we face in their diagnosis and therapeutic approach. We hope that this overview will lead to a better awareness of the spectrum of demyelinating diseases of the central nervous system in Indonesia.…”
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  2. 6742
    “…This review aims to provide a complete overview of studies that employ computational tools to obtain a better fundamental understanding of the self-assembly behavior of supramolecular gels or to accelerate their development by means of prediction. As such, we hope to stimulate researchers to consider using computational tools when investigating these intriguing materials. …”
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  3. 6743
    por Mrsny, Randall J., Mahmood, Tahir A.
    Publicado 2021
    “…While these initial opportunities have provided more than just a glimmer of hope within the industry, there are important aspects of oral biopharmaceutical delivery that do not completely align with pharmacokinetic (PK) parameters and pharmacodynamics (PD) outcomes that have been learned from parenteral administrations. …”
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  4. 6744
    “…Recent therapeutic advances have given hope to families and patients by compensating for the deficiency in survival motor neuron (SMN) protein via gene therapy or other genetic manipulation. …”
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  5. 6745
    “…Given the vital role of innate immunity, harnessing these immune responses opens up new hope for the generation of long-lasting and protective immunity against COVID-19.…”
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  6. 6746
    por Wang, Cheng-Bin, He, Li
    Publicado 2021
    “…BACKGROUND: The genus Anoplophora Hope, 1839 (Coleoptera: Cerambycidae: Lamiinae: Lamiini) includes 47 species (without subspecies) occurring in East, South and Southeast Asia. …”
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  7. 6747
    “…The complete system of shared values concerning the research process is embedded in the concept of research culture, which has been gaining more attention in recent years. With the hope of increasing awareness of research culture among established scientists and early-career professionals, in this manuscript we discuss what research culture is, what it consists of and how it can positively influence scientific developments.…”
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  8. 6748
    “…With advances in available research tools leading to a better understanding of the mitochondria in health and disease, there is hope for novel treatment options in the future.…”
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  9. 6749
    “…By presenting our design in this paper, we hope there will be much more chances for higher service-oriented developments utilizing bio-signals in the future.…”
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  10. 6750
    “…In the past decades, major steps have been made to bring nanotechnology into the clinic in the form of nanoparticle-based drug delivery systems. The great hope of drug delivery systems is to reduce the side effects of chemotherapeutics while simultaneously increasing the efficiency of the therapy. …”
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  11. 6751
    por Joshi, Tejas P., Duvic, Madeleine
    Publicado 2021
    “…In this review, we summarize recent updates on GA epidemiology and etiopathogenesis and offer an updated review of the therapeutic options for GA currently reported in the literature. We hope that the current review galvanizes randomized controlled studies that will in turn help lead to the recommendation of evidence-based treatments for GA.…”
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  12. 6752
    “…Ultimately, the patient’s goals of care transitioned to palliation, and treatments were discontinued. It is our hope that in the future, such outcomes might be prevented by considering disseminated histoplasmosis in systemically unwell patients with HIV, regardless of endemic exposure or specific presentation.…”
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  13. 6753
    “…In addition, 20 cases of APRT deficiency in renal transplant recipients were also reviewed. We hope this case increases awareness of APRT deficiency in repeated obstructive nephropathy post-transplantation, which is a treatable disease for which the misdiagnosis or delayed diagnosis should be avoided.…”
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  14. 6754
    por von Werder, Marten, Rukwid, Ralf
    Publicado 2021
    “…In many places, employees fear for their jobs and hope for more on-the-job training and a targeted, active industrial policy — this is a challenge for the next federal government.…”
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  15. 6755
    “…Machine learning brings the hope of finding new biomarkers extracted from cohorts with rich biomedical measurements. …”
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  16. 6756
    “…In this review, we aim to offer a comprehensive overview of the human mycobiome in healthy and diseased states in a systematic way. The authors hope that the reader will utilize this review as a scaffolding to formulate their understanding of the mycobiome and pursue further research.…”
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  17. 6757
    por Zeng, Yonghong, Guo, Zhinan
    Publicado 2021
    “…Finally, we propose a selection rule of preparation methods of few-layer BP according to the requirement of specific BP properties for different applications. We hope this review would bring some insight for future researches on BP and contributes to the acceleration of BP's commercial progress.…”
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  18. 6758
    por Vallat, Raphael, Walker, Matthew P
    Publicado 2021
    “…The software is designed to be especially easy to use, computationally low-demanding, open source, and free. Our hope is that this software facilitates the broad adoption of an industry-standard automated sleep staging software package.…”
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  19. 6759
    “…Finally, a few application scenarios and impacts of CPCV are listed, which includes how CPVC simplify automation of microfluidic networks, work with other driving modes; make extensive use of microfluidics by open channel, and sampling and delivery with controlled manners. The authors hope this review will help the development and use of the CPCV in microfluidic fields in both research and industry.…”
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  20. 6760
    “…The technical challenges of dialyzers are also highlighted in this review, which discusses the research areas that need to be prioritized to further improve the properties of dialyzers, such as flux, biocompatibility, flow distribution and urea clearance rate. We hope this review article can provide insights to researchers in developing/designing an ideal dialyzer that can bring the best hemodialysis treatment outcomes to kidney disease patients.…”
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