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691501por Brewer, Kelly, Sisk, Ryan, Lee, Hyejin, Elisabeth Moolhuijsen, Loes Melanie, van der Ham, Kim, Louwers, Yvonne, Visser, Jenny A, Dapas, Matthew, Franks, Stephen, Laven, Joop S E, Li, Chun, Dunaif, Andrea Elizabeth“…The KA cohort, 417 cases and 926 controls, was genotyped with the HumanOmni1-Quad v1 array. The imputation of previously reported genotype data was updated using the larger, more deeply sequenced TOPMed (R2) imputation panel. …”
Publicado 2023
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691502por Yuksel, Simge, Lopez Fanas, Raul, Schwartz, Deborah, Tabatabaie, Vafa, Sachdev, Saachi“…Introduction: Adult T-cell leukemia/lymphoma (ATLL) is a rare, aggressive lymphoproliferative disorder associated with human T-cell leukemia virus type 1 (HTLV-1), often presenting with severe refractory hypercalcemia. …”
Publicado 2023
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691503por Oliveira, Talita Fischer, Oliveira, Talita Fernanda, da Penha, Karine Lopes, Santana, Dayane Campos, Lunardi Rocha, Ana Luiza, Reis, Fernando M, Premaor, Melissa Orlandin, Candido, Ana Lucia, Comim, Fabio Vasconcellos“…Hirsutism was defined as mFG > 6 for South Americans [the criteria suggested by the Endocrine Society (ES)] or mFG > 4 [European Society of Human Reproduction and Embryology (ESHRE)]. Overall, 199 women were evaluated. …”
Publicado 2023
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691504por Fowler, Melissa A, Regan, Collin, Zhao, Jian, Coutinho, Eulalia, Fleck, Beth, Castellanos, Anel A, Muller, Eric, Johns, Michael, Tang, Yang, Sturchler, Emmanuel, Chen, Mi, Retting, Kelsey, Dalvie, Deepak, Betz, Stephen F, Markison, Stacy“…One analog, TSHRant-1, demonstrated potent negative allosteric modulator activity at both the human and rat TSHR. To evaluate the in vivo pharmacodynamics of TSHant-1, we developed a rat model of hyperthyroidism. …”
Publicado 2023
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691505“…World J Diabetes. 2021 May 15;12(5):514-523. 2) Tariq M, et al. Prolonged culture of human pancreatic islets under glucotoxic conditions changes their acute beta cell calcium and insulin secretion glucose response curves from sigmoid to bell-shaped. …”
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691506por Braslavsky, Debora Giselle, Keselman, Ana Claudia, Ballerini, Maria Gabriela, Rosenbrock, Solange, Cappa, Nicolas, Negrete, Gabriel, Dech, Gaston, Ropelato, Maria Gabriela, Gamio, Susana, Bergada, Ignacio“…Background Current safety of recombinant human growth hormone (rhGH) treatment arises mainly from postmarketing surveillance. …”
Publicado 2023
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691507“…These data also suggest a potential model to study the mechanisms mediating the effect of miR-93 overexpression on IR and on the PCOS phenotype in tissues and conditions not readily accessible in human subjects. Presentation Date: Saturday, June 17, 2023…”
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691508por Klein, Karen O, Backeljauw, Philippe, Abdelrahman, Sohair, Lai, Pamela, Mao, Meng, Shu, Aimee“…At this time, individuals with TS are treated with daily somatropin (human growth hormone [hGH]) which is effective at promoting height gain and may improve body composition. …”
Publicado 2023
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691509por Zhao, Xiaoxuan, Jiang, Yuepeng, Ma, Xiao, Yang, Qujia, Ding, Xinyi, Wang, Hanzhi, Yao, Xintong, Jin, Linxi, Zhang, Qin“…Employing a variety of machine learning techniques, including one‐way logistic regression, LASSO regression, random forest and artificial neural networks, we screened 11 signature genes from the intersection of immune‐associated DEGs and secretory protein‐encoding genes derived from the Human Protein Atlas. Notably, CCL18 and IFNA4 emerged as prospective peripheral blood markers capable of identifying PTE‐induced immune disorders. …”
Publicado 2023
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691510por Chen, Na, Li, Jingyu, Li, Yexing, Zhang, Yiyuan, Li, Jiarong, Gao, Jie, Hu, Jingmei, Cui, Linlin, Chen, Zi-JiangEnlace del recurso
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691511por Muñoz, Juan Pablo, Larrosa, Cristina, Chamorro, Saray, Perez-Jaume, Sara, Simao, Margarida, Sanchez-Sierra, Nazaret, Varo, Amalia, Gorostegui, Maite, Castañeda, Alicia, Garraus, Moira, Lopez-Miralles, Sandra, Mora, Jaume“…We investigated the combination of humanized anti-GD2 mAb naxitamab (Hu3F8), irinotecan (I), temozolomide (T), and sargramostim (GM-CSF)—HITS—against primary resistant HR-NB. …”
Publicado 2023
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691512por Haun, Jolie N, Venkatachalam, Hari H, Fowler, Christopher A, Alman, Amy C, Ballistrea, Lisa M, Schneider, Tali, Benzinger, Rachel C, Melillo, Christine, Alexander, Neil B, Klanchar, S Angelina, Lapcevic, William, French, Dustin D“…Participant recommendations for reducing attrition included switching to digital forms to reduce participant burden and increasing human interaction throughout the registration and baseline data collection processes. …”
Publicado 2023
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691513
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691514por Looareesuwan, Panita, Krudsood, Srivicha, Lawpoolsri, Saranath, Tangpukdee, Noppadon, Matsee, Wasin, Nguitragool, Wang, Wilairatana, Polrat“…Despite significant progress, one of the key challenges to malaria elimination are undetected gametocyte carriers. Human migration adds complexity to the malaria situation, as it not only sustains local transmission but also poses the risk of spreading drug-resistant parasites. …”
Publicado 2023
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691515“…Unlike other health promotion programs, Hans Kai is grounded in a holistic model of health that simultaneously addresses multiple determinants of health at different levels of human ecology. In Hans Kai, a set of informational sessions that are delivered in a group setting by healthcare professionals are followed by regular peer-led group meetings in a self-governed support group setting that is designed to promote implementation of newly learned health competences. …”
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691516por Schmitz, Renée S J M, van den Belt-Dusebout, Alexandra W, Clements, Karen, Ren, Yi, Cresta, Chiara, Timbres, Jasmine, Liu, Yat-Hee, Byng, Danalyn, Lynch, Thomas, Menegaz, Brian A, Collyar, Deborah, Hyslop, Terry, Thomas, Samantha, Love, Jason K, Schaapveld, Michael, Bhattacharjee, Proteeti, Ryser, Marc D, Sawyer, Elinor, Hwang, E Shelley, Thompson, Alastair, Wesseling, Jelle, Lips, Esther H, Schmidt, Marjanka K, Nik-Zainal, Serena, Davies, Helen, Futreal, Andrew, Navin, Nicholas, Jonkers, Jos, van Rheenen, Jacco, Behbod, Fariba, Wessels, Lodewyk F A, Rea, Daniel, Stobart, Hilary, Pinto, Donna, Verschuur, Ellen, van Oirsouw, Marja“…Associations between larger DCIS and hormone receptor negative and human epidermal growth factor receptor 2 positive ipsilateral invasive breast cancer and involved margins and hormone receptor negative ipsilateral invasive breast cancer were found. …”
Publicado 2023
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691517por Kelly, Hayden Thomas, Smith, Jordan James, Verdonschot, Angeliek, Kennedy, Sarah Grace, Scott, Joseph J, McKay, Heather, Nathan, Nicole, Sutherland, Rachel, Morgan, Philip James, Salmon, Jo, Penney, Dawn, Boyer, James, Lloyd, Rhodri S, Oldmeadow, Christopher, Reeves, Penny, Pursey, Kirrilly, Hua, Myna, Longmore, Sarah, Norman, Jennifer, Voukelatos, Alexander, Zask, Avigdor, Lubans, David Revalds“…ETHICS AND DISSEMINATION: Ethics approval has been obtained from the University of Newcastle (H-2021-0418), the NSW Department of Education (SERAP:2022215), Hunter New England Human Research Ethics Committee (2023/ETH00052) and the Catholic Schools Office. …”
Publicado 2023
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691518por van Hoogenhuijze, Nienke E, Lahoz Casarramona, Gemma, Lensen, Sarah, Farquhar, Cindy, Kamath, Mohan S, Kunjummen, Aleyamma T, Raine-Fenning, Nick, Berntsen, Sine, Pinborg, Anja, Mackens, Shari, Inal, Zeynep Ozturk, Ng, Ernest H Y, Mak, Jennifer S M, Narvekar, Sachin A, Martins, Wellington P, Steengaard Olesen, Mia, Torrance, Helen L, Mol, Ben W, Eijkemans, Marinus J C, Wang, Rui, Broekmans, Frank J MEnlace del recurso
Publicado 2023
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691519
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691520por Nazarov, Anthony, Fikretoglu, Deniz, Liu, Aihua, Born, Jennifer, Michaud, Kathy, Hendriks, Tonya, Bélanger, Stéphanie AH, Do, Minh T, Lam, Quan, Brooks, Brenda, King, Kristen, Sudom, Kerry, Jetly, Rakesh, Garber, Bryan, Thompson, Megan“…Akin to what was observed following past CAF international humanitarian missions, there was an expected increased risk of exposure to multiple stressors that may be psychologically traumatic and potentially morally injurious in nature (ie, related to core values, eg, witnessing human suffering). Emerging data from health care workers exposed to the unprecedented medical challenges and dilemmas of the early pandemic stages also indicated that such experiences were associated with increased risk of adverse mental health outcomes. …”
Publicado 2023
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