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691901por Biolchi, Alessia, Tomei, Sara, Santini, Laura, Gaetana, Rita La, Mori, Elena, Novy, Patricia, Rappuoli, Rino, Bekkat-Berkani, Rafik, Giuliani, Marzia Monica, Pizza, Mariagrazia, Sciences, Biological“…We tested individual sera collected from a subgroup of 20 US participants at pre-vaccination and 1 month post-second dose in a serum bactericidal assay with human complement (hSBA) against the meningococcal strain panel. …”
Publicado 2020
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691902por Levin, James, Amundson, Karin, Borchardt, Allen, Lam, Thanh, Brady, Tom, Abelovski, Elizabeth, Döhrmann, Simon, Cole, Jason, Ong, Voon, Tari, Les“…BACKGROUND: Cidara’s AVCs are novel, potent, antiviral agents conjugated with the Fc domain of human IgG1. CD377 is an AVC development candidate being evaluated for prevention and treatment of seasonal and pandemic influenza, including in immune-deficient populations unable to benefit from vaccination. …”
Publicado 2020
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691903por Ison, Michael G, Chao, Nelson, Marty, Francisco M, Moon, Seung Hyun, Zhang, Zhiji, Chandak, Aastha“…BACKGROUND: Respiratory viruses (RV), including respiratory syncytial virus (RSV), influenza, parainfluenza virus (PIV), and human metapneumovirus (HMPV), frequently lead to serious complications such as lower respiratory tract infections and death in allogeneic hematopoietic cell transplantation (HCT) recipients. …”
Publicado 2020
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691904por Harper, Eugene P, Oring, Justin, Powers, Harry, Sherman, Courtney E, Wilke, Benjamin, Hata, Jane, Nassar, Aziza, Mendez, Julio C, Libertin, Claudia R“…BACKGROUND: Echinococcus multilocularis is a destructive zoonotic cestode with low human incidence. Hydatid disease classically presents with hepatic or lung involvement with infrequent extrahepatic bone destruction. …”
Publicado 2020
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691905por Asempa, Tomefa E, DeRosa, Nicole A, Cassino, Cara, Lehoux, Dario, Schuch, Raymond, Nicolau, David P“…Murine ICR MIC (100% serum) and human MIC (100% serum) for CF-296 ranged from 32-256 mg/L to 0.5-1 mg/L respectively. …”
Publicado 2020
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691906por Deshpande, Lalitagauri M, Collingsworth, Timothy, Mendes, Rodrigo E, Castanheira, Mariana“…(Research Grant or Support)Department of Health and Human Services (Research Grant or Support)GlaxoSmithKline (Research Grant or Support)Melinta Therapeutics, Inc. …”
Publicado 2020
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691907por Critchley, Ian A, Cotroneo, Nicole S, Pucci, Michael J, Jain, Akash, Mendes, Rodrigo E“…(Research Grant or Support)Department of Health and Human Services (Research Grant or Support)GlaxoSmithKline (Research Grant or Support)Melinta Therapeutics, Inc. …”
Publicado 2020
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691908por Mieguim Ngninpogni, Dominique, Ndo, Cyrille, Ntonga Akono, Patrick, Nguemo, Anicet, Nguepi, Amine, Metitsi, Danale Rosine, Tombi, Jeannette, Awono-Ambene, Parfait, Bilong Bilong, Charles Félix“…Adult mosquitoes were collected using the human landing catch (HLC) method and identified using morphological and molecular techniques. …”
Publicado 2021
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691909
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691910por Tobi, Elmar W, Almqvist, Catarina, Hedman, Anna, Andolf, Ellika, Holte, Jan, Olofsson, Jan I, Wramsby, Håkan, Wramsby, Margaretha, Pershagen, Göran, Heijmans, Bastiaan T, Iliadou, Anastasia NEnlace del recurso
Publicado 2020
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691911por Huang, Pei-yan, Wu, Jun-guo, Gu, Jun, Zhang, Tie-qi, Li, Ling-feng, Wang, Si-qun, Wang, Minghai“…Furthermore, 56 target genes that negatively correlated with the DEMs were predicted and found to be enriched in three functional terms (e.g., positive regulation of intracellular protein transport) and three pathways (e.g., human cytomegalovirus infection). In addition, three key miRNAs (miR-98-5p, miR-7-5p, and miR-182-5p) and six key genes (murine double minute 2, MDM2; glycogen synthase kinase 3-beta, GSK3B; transmembrane P24-trafficking protein 10, TMED10; DDB1 and CUL4-associated factor 12, DCAF12; caspase 3, CASP3; and ring finger protein 44, RNF44) were screened, among which the miR-7-5p → TMED10/DCAF12, miR-98-5p → CASP3/RNF44, and miR-182-5p → GSK3B pairs were observed in the regulatory network. …”
Publicado 2021
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691912por Brickwood, Katie-Jane, Ahuja, Kiran D K, Watson, Greig, O'Brien, Jane A, Williams, Andrew D“…This trial was approved by the Tasmanian Health and Medical Human Research Ethics Committee (H0014713). RESULTS: A total of 117 participants were randomized to the study (AT, n=37; TC, n=38; UC, n=42). …”
Publicado 2021
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691913“…Trial registration: The experimental protocol was established, according to the ethical guidelines of the Helsinki Declaration and was approved by the Human Ethics Committee of The Second Affiliated hospital of Zhejiang University School of Medicine (IR2019001235). …”
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691914por Ruiz-Ripa, Laura, Simón, Carmen, Ceballos, Sara, Ortega, Carmelo, Zarazaga, Myriam, Torres, Carmen, Gómez-Sanz, Elena“…According to animal clinical history and data records, several strains seem to have been acquired from different sources of the hospital environment, while some SA strains appeared to have a human origin. CONCLUSIONS: The frequent detection of MR and MDR isolates among clinical SP and SA strains with noticeable virulence traits is of veterinary concern, implying limited treatment options available. …”
Publicado 2021
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691915por Petrunoff, Nicholas, Yao, Jiali, Sia, Angelia, Ng, Alwyn, Ramiah, Anbumalar, Wong, Michael, Han, Jane, Tai, Bee Choo, Uijtdewilligen, Léonie, Müller-Riemenschneider, Falk“…Prioritising time with family and preferences for unstructured activities were barriers to intervention participation. Human interaction via follow-up or group exercise were facilitators. …”
Publicado 2021
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691916por Duri, Kerina, Chimhuya, Simbarashe, Gomo, Exnevia, Munjoma, Privilege Tendai, Chandiwana, Panashe, Yindom, Louis Marie, Mhandire, Kudakwashe, Ziruma, Asaph, Mtapuri-Zinyowera, Sekesai, Mazengera, Lovemore Ronald, Misselwitz, Benjamin, Gumbo, Felicity Zvanyadza, Jordi, Sebastian, Rowland-Jones, Sarah“…INTRODUCTION: Despite being a leading infectious cause of childhood disability globally, testing for cytomegalovirus (CMV) infections in pregnancy is generally not done in Sub-Sahara Africa (SSA), where breastfeeding practice is almost universal. Whilst CMV and human immunodeficiency virus (HIV) are both endemic in SSA, the relationship between antenatal plasma CMV-DNA, HIV-1-RNA levels and HIV-1-mother to child transmission (MTCT) including pregnancy outcomes remains poorly described. …”
Publicado 2021
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691917por Wang, Yu, Lu, Cheng, Li, Hao, Qi, Wensheng, Ruan, Lianguo, Bian, Yongjun, Shi, Huaxin, Song, Hui, Tu, Shengjin, Zhang, Yan, Bai, Tao, Cao, Rong, Hong, Ke, Li, Huadong, Liu, Li, Lu, Sixia, Rong, Nianhe, Liu, Yue, Fang, Jiliang, Shi, Jiaheng, Yang, Wei, Zhao, Bin, Yang, Yang, Zhao, Yufeng, Li, Shaoyuan, Fan, Tiebing, Rong, Peijing, Huang, Luqi“…In addition, patients in both groups received routine supportive treatment, including oxygen inhalation, symptomatic therapy, and/or human intravenous immunoglobulin, and/or serum albumin, and treatment for underlying diseases. …”
Publicado 2021
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691919por Thomsen, Reimar W., Christiansen, Christian Fynbo, Heide-Jørgensen, Uffe, Vogelstein, Joshua T., Vogelstein, Bert, Bettegowda, Chetan, Tamang, Suzanne, Athey, Susan, Sørensen, Henrik Toft“…However, studies of the association of α1-blockers with outcomes among human participants with respiratory tract infections are scarce. …”
Publicado 2021
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691920por Chinta, Parimala, Antonisamy, Belavendra, Mangalaraj, Ann M, Kunjummen, Aleyamma T, Kamath, Mohan SEnlace del recurso
Publicado 2021
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